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Q57764 (PDAD_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvoyl-dependent arginine decarboxylase
Short name=PvlArgDC
EC=4.1.1.19

Cleaved into the following 2 chains:

  1. Pyruvoyl-dependent arginine decarboxylase subunit beta
  2. Pyruvoyl-dependent arginine decarboxylase subunit alpha
Gene names
Name:pdaD
Ordered Locus Names:MJ0316
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus ›

Protein attributes

Sequence length165 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01404

Cofactor

Pyruvoyl group.

Subunit structure

Trimer of an alpha-beta dimer.

Sequence similarities

Belongs to the PdaD family.

Biophysicochemical properties

Temperature dependence:

Thermostable. HAMAP-Rule MF_01404

Mass spectrometry

Molecular mass is 5436±11 Da from positions 1 - 52. Determined by MALDI. Ref.2

Molecular mass is 12356±57 Da from positions 53 - 165. Determined by MALDI. Ref.2

Ontologies

Keywords
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionarginine decarboxylase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 5252Pyruvoyl-dependent arginine decarboxylase subunit beta HAMAP-Rule MF_01404
PRO_0000023314
Chain53 – 165113Pyruvoyl-dependent arginine decarboxylase subunit alpha HAMAP-Rule MF_01404
PRO_0000023315

Sites

Site52 – 532Cleavage (non-hydrolytic)

Amino acid modifications

Modified residue531Pyruvic acid (Ser) HAMAP-Rule MF_01404

Secondary structure

1 ................... 165
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q57764 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 04C7F8AB3AEC2342

FASTA16517,708
        10         20         30         40         50         60 
MNAEINPLHA YFKLPNTVSL VAGSSEGETP LNAFDGALLN AGIGNVNLIR ISSIMPPEAE 

        70         80         90        100        110        120 
IVPLPKLPMG ALVPTAYGYI ISDVPGETIS AAISVAIPKD KSLCGLIMEY EGKCSKKEAE 

       130        140        150        160 
KTVREMAKIG FEMRGWELDR IESIAVEHTV EKLGCAFAAA ALWYK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L77117 Genomic DNA. Translation: AAB98302.1.
PIRE64339.
RefSeqNP_247289.1. NC_000909.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1MT1X-ray2.20A/C/E/G/I/K1-52[»]
B/D/F/H/J/L54-165[»]
1N13X-ray1.40A/C/E/G/I/K1-52[»]
B/D/F/H/J/L54-165[»]
1N2MX-ray1.90A/B/C/D/E/F1-165[»]
2QQCX-ray2.00A/C/E/G/I/K1-52[»]
B/D/F/H/J/L54-165[»]
2QQDX-ray2.00A/D1-52[»]
B/E54-165[»]
C/F/G/H1-165[»]
ProteinModelPortalQ57764.
SMRQ57764. Positions 3-165.
ModBaseSearch...

Protein-protein interaction databases

STRING243232.MJ0316.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98302; AAB98302; MJ_0316.
GeneID1451171.
KEGGmja:MJ_0316.

Phylogenomic databases

eggNOGCOG1945.
KOK02626.
OMAISSIMPP.
ProtClustDBPRK01285.

Enzyme and pathway databases

SABIO-RKQ57764.

Family and domain databases

Gene3D3.50.20.10. 1 hit.
HAMAPMF_01404. PvlArgDC.
InterProIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56271. His_carbxylase. 1 hit.
TIGRFAMsTIGR00286. TIGR00286. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ57764.

Entry information

Entry namePDAD_METJA
AccessionPrimary (citable) accession number: Q57764
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 1, 2013
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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