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Protein

Small heat shock protein HSP16.5

Gene

MJ0285

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Chaperone that confers thermal protection to other proteins.

GO - Molecular functioni

  • identical protein binding Source: CAFA

GO - Biological processi

  • protein homooligomerization Source: CAFA
  • protein stabilization Source: CAFA

Keywordsi

Molecular functionChaperone
Biological processStress response

Enzyme and pathway databases

BioCyciMJAN243232:G1GKE-307-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Small heat shock protein HSP16.5
Gene namesi
Ordered Locus Names:MJ0285
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB-SubCell
  • protein-containing complex Source: CAFA

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260601 – 147Small heat shock protein HSP16.5Add BLAST147

Interactioni

Subunit structurei

Homooligomer of 24 subunits. Forms a spherical shape.

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-15555697,EBI-15555697

GO - Molecular functioni

  • identical protein binding Source: CAFA

Protein-protein interaction databases

DIPiDIP-48450N
STRINGi243232.MJ_0285

Structurei

Secondary structure

1147
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi36 – 41Combined sources6
Beta strandi45 – 49Combined sources5
Beta strandi51 – 59Combined sources9
Helixi65 – 67Combined sources3
Beta strandi68 – 73Combined sources6
Beta strandi76 – 82Combined sources7
Beta strandi93 – 97Combined sources5
Beta strandi104 – 110Combined sources7
Helixi117 – 119Combined sources3
Beta strandi121 – 125Combined sources5
Beta strandi128 – 135Combined sources8
Helixi137 – 139Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1SHSX-ray2.90A/B/C/D/E/F/G/H1-147[»]
4ELDX-ray2.70A/B1-147[»]
4I88X-ray2.85A/B/C/D/E/F/G/H1-147[»]
DisProtiDP00067
ProteinModelPortaliQ57733
SMRiQ57733
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57733

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 147sHSPPROSITE-ProRule annotationAdd BLAST112

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiarCOG01832 Archaea
COG0071 LUCA
InParanoidiQ57733
KOiK13993
OMAiSGKGFMP
OrthoDBiPOG093Z0DGJ
PhylomeDBiQ57733

Family and domain databases

Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR008978 HSP20-like_chaperone
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Complete.

Q57733-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFGRDPFDSL FERMFKEFFA TPMTGTTMIQ SSTGIQISGK GFMPISIIEG
60 70 80 90 100
DQHIKVIAWL PGVNKEDIIL NAVGDTLEIR AKRSPLMITE SERIIYSEIP
110 120 130 140
EEEEIYRTIK LPATVKEENA SAKFENGVLS VILPKAESSI KKGINIE
Length:147
Mass (Da):16,452
Last modified:November 1, 1996 - v1
Checksum:i0A53C6981CFD4266
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB98273.1
PIRiF64335
RefSeqiWP_010869783.1, NC_000909.1

Genome annotation databases

EnsemblBacteriaiAAB98273; AAB98273; MJ_0285
GeneIDi1451140
KEGGimja:MJ_0285

Entry informationi

Entry nameiHSPS_METJA
AccessioniPrimary (citable) accession number: Q57733
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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