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Protein

Small heat shock protein HSP16.5

Gene

MJ0285

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Chaperone that confers thermal protection to other proteins.

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Small heat shock protein HSP16.5
Gene namesi
Ordered Locus Names:MJ0285
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 147147Small heat shock protein HSP16.5PRO_0000126060Add
BLAST

Interactioni

Subunit structurei

Homooligomer of 24 subunits. Forms a spherical shape.

Protein-protein interaction databases

DIPiDIP-48450N.
STRINGi243232.MJ0285.

Structurei

Secondary structure

1
147
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi36 – 416Combined sources
Beta strandi45 – 495Combined sources
Beta strandi51 – 599Combined sources
Helixi65 – 673Combined sources
Beta strandi68 – 736Combined sources
Beta strandi76 – 827Combined sources
Beta strandi93 – 975Combined sources
Beta strandi104 – 1107Combined sources
Helixi117 – 1193Combined sources
Beta strandi121 – 1255Combined sources
Beta strandi128 – 1358Combined sources
Helixi137 – 1393Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SHSX-ray2.90A/B/C/D/E/F/G/H1-147[»]
4ELDX-ray2.70A/B1-147[»]
4I88X-ray2.85A/B/C/D/E/F/G/H1-147[»]
DisProtiDP00067.
ProteinModelPortaliQ57733.
SMRiQ57733. Positions 33-147.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57733.

Family & Domainsi

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0071.
InParanoidiQ57733.
KOiK13993.
OMAiISGKGFM.
PhylomeDBiQ57733.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR002068. a-crystallin/Hsp20_dom.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57733-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFGRDPFDSL FERMFKEFFA TPMTGTTMIQ SSTGIQISGK GFMPISIIEG
60 70 80 90 100
DQHIKVIAWL PGVNKEDIIL NAVGDTLEIR AKRSPLMITE SERIIYSEIP
110 120 130 140
EEEEIYRTIK LPATVKEENA SAKFENGVLS VILPKAESSI KKGINIE
Length:147
Mass (Da):16,452
Last modified:November 1, 1996 - v1
Checksum:i0A53C6981CFD4266
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98273.1.
PIRiF64335.
RefSeqiNP_247258.1. NC_000909.1.
WP_010869783.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98273; AAB98273; MJ_0285.
GeneIDi1451140.
KEGGimja:MJ_0285.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98273.1.
PIRiF64335.
RefSeqiNP_247258.1. NC_000909.1.
WP_010869783.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SHSX-ray2.90A/B/C/D/E/F/G/H1-147[»]
4ELDX-ray2.70A/B1-147[»]
4I88X-ray2.85A/B/C/D/E/F/G/H1-147[»]
DisProtiDP00067.
ProteinModelPortaliQ57733.
SMRiQ57733. Positions 33-147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48450N.
STRINGi243232.MJ0285.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB98273; AAB98273; MJ_0285.
GeneIDi1451140.
KEGGimja:MJ_0285.

Phylogenomic databases

eggNOGiCOG0071.
InParanoidiQ57733.
KOiK13993.
OMAiISGKGFM.
PhylomeDBiQ57733.

Miscellaneous databases

EvolutionaryTraceiQ57733.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR002068. a-crystallin/Hsp20_dom.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  2. "Small heat shock protein of Methanococcus jannaschii, a hyperthermophile."
    Kim R., Kim K.K., Yokota H., Kim S.-H.
    Proc. Natl. Acad. Sci. U.S.A. 95:9129-9133(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  3. "Crystal structure of a small heat-shock protein."
    Kim K.K., Kim R., Kim S.-H.
    Nature 394:595-599(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Entry informationi

Entry nameiHSPS_METJA
AccessioniPrimary (citable) accession number: Q57733
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: February 4, 2015
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.