Reviewed, UniProtKB/Swiss-Prot Q57729 (AMZA_METJA)

Names and origin

Protein names

Recommended name:
Archaemetzincin
EC=3.-.-.-

Gene names

Name:	amzA
Ordered Locus Names:	MJ0281

Organism

Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP]

Taxonomic identifier

2190 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Probable zinc metalloprotease By similarity. HAMAP MF_01842
Sequence similarities	Belongs to the peptidase M54 family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Hydrolase Metalloprotease Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	metallopeptidase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 179	179	Archaemetzincin HAMAP MF_01842		PRO_0000159626
Sites
	Active site	129	1	By similarity
	Metal binding	128	1	Zinc; catalytic By similarity
	Metal binding	132	1	Zinc; catalytic By similarity
	Metal binding	139	1	Zinc; catalytic Potential

Sequences

	Sequence		Length	Mass (Da)
	Q57729-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 895A7E935A757CE8	FASTA	179	20,514
	10 20 30 40 50 60 MVMIMRICIQ PVGDVNDEIL KFLKKKFGEV FGMCEILPKI DIPIYAYNFS RGQFNSTLIL 70 80 90 100 110 120 KSLPTVEDIV LGVTEVDIYA DNLNFVFGEA ELFGKRALIS LARLRPEFYG LPPNKDVLKI 130 140 150 160 170 RALKEAIHEI GHVLGLIHCE NKRCVMSFSN SIIDVDLKDW RYCKKCLKKL QDRGIYISI

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98269.1.
PIR	B64335.
RefSeq	NP_247254.1.
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	M54.001.
Genome annotation databases
GeneID	1451136.
GenomeReviews	Gene locus MJ0281 in contig L77117_GR.
KEGG	mja:MJ0281.
NMPDR	fig|243232.1.peg.291.
TIGR	MJ0281.
Phylogenomic databases
HOGENOM	HBG508786.
OMA	EIFLERA.
Family and domain databases
HAMAP	MF_01842. Archaemetzincin. [Tree]
InterPro	IPR012962. Pept_M54_archaemetzncn. IPR012091. Pept_M54_archaemetzncn_arc/bac. [Graphical view]
Pfam	PF07998. Peptidase_M54. 1 hit. [Graphical view]
PIRSF	PIRSF005785. Zn-prot_arch. 1 hit.
PROSITE	PS00142. ZINC_PROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AMZA_METJA

Accession

Primary (citable) accession number: Q57729

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	January 19, 2010
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)