Q57729 (AMZA_METJA) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Archaemetzincin EC=3.4.-.- | ||||
| Gene names |
| ||||
| Organism | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP] | ||||
| Taxonomic identifier | 243232 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › ![]() |
Protein attributes
| Sequence length | 179 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Probable zinc metalloprotease whose natural substrate is unknown By similarity. HAMAP-Rule MF_01842 |
| Cofactor | Binds 2 zinc ions per subunit. One is catalytic, whereas the other seems to have a structural role By similarity. |
| Subunit structure | Monomer By similarity. |
| Sequence similarities | Belongs to the peptidase M54 family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Metal-binding Zinc |
| Molecular function | Hydrolase Metalloprotease Protease |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | proteolysis Inferred from electronic annotation. Source: HAMAP |
| Molecular_function | metallopeptidase activity Inferred from electronic annotation. Source: HAMAP zinc ion bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 179 | 179 | Archaemetzincin HAMAP-Rule MF_01842 | PRO_0000159626 | |||||
Sites | |||||||||
| Active site | 129 | 1 | Proton acceptor By similarity | ||||||
| Metal binding | 128 | 1 | Zinc 1; catalytic; via tele nitrogen By similarity | ||||||
| Metal binding | 132 | 1 | Zinc 1; catalytic; via tele nitrogen By similarity | ||||||
| Metal binding | 138 | 1 | Zinc 1; catalytic; via tele nitrogen By similarity | ||||||
| Metal binding | 139 | 1 | Zinc 2 By similarity | ||||||
| Metal binding | 144 | 1 | Zinc 2 By similarity | ||||||
| Metal binding | 163 | 1 | Zinc 2 By similarity | ||||||
| Metal binding | 166 | 1 | Zinc 2 By similarity | ||||||
Sequences
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References
| [1] | "Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. Venter J.C.Science 273:1058-1073(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L77117 Genomic DNA. Translation: AAB98269.1. |
| PIR | B64335. |
| RefSeq | NP_247254.1. NC_000909.1. |
3D structure databases | |
| ProteinModelPortal | Q57729. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 243232.MJ0281. |
Protein family/group databases | |
| MEROPS | M54.001. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AAB98269; AAB98269; MJ_0281. |
| GeneID | 1451136. |
| KEGG | mja:MJ_0281. |
Phylogenomic databases | |
| eggNOG | COG1913. |
| KO | K06974. |
| OMA | CVISIAR. |
| ProtClustDB | CLSK2749866. |
Family and domain databases | |
| Gene3D | 3.40.390.10. 1 hit. |
| HAMAP | MF_01842. Archaemetzincin. |
| InterPro | IPR024079. MetalloPept_cat_dom. IPR012962. Pept_M54_archaemetzincn. IPR012091. Pept_M54_archaemetzncn_arc/bac. [Graphical view] |
| Pfam | PF07998. Peptidase_M54. 1 hit. [Graphical view] |
| PIRSF | PIRSF005785. Zn-prot_arch. 1 hit. |
| PROSITE | PS00142. ZINC_PROTEASE. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AMZA_METJA | ||||||||
| Accession | Primary (citable) accession number: Q57729 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Peptidase families Classification of peptidase families and list of entries |
| Methanococcus jannaschii Methanococcus jannaschii: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with
