Q57728 (NAC_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nascent polypeptide-associated complex protein

Gene names

Name:	nac
Ordered Locus Names:	MJ0280

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › Methanocaldococcus jannaschii

Protein attributes

Sequence length	128 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Contacts the emerging nascent chain on the ribosome By similarity. HAMAP-Rule MF_00814
Subunit structure	Homodimer. Interacts with the ribosome. Binds ribosomal RNA By similarity.
Sequence similarities	Belongs to the NAC-alpha family. Contains 1 NAC-A/B (NAC-alpha/beta) domain. Contains 1 UBA domain.

Ontologies

Keywords
Biological process	Protein transport Transport
Ligand	RNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein transport Inferred from electronic annotation. Source: HAMAP
Molecular_function	RNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 128	128	Nascent polypeptide-associated complex protein HAMAP-Rule MF_00814		PRO_0000135601
Regions
	Domain	8 – 75	68	NAC-A/B
	Domain	84 – 122	39	UBA

Sequences

	Sequence		Length	Mass (Da)
	Q57728 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: CE6B571273455E8D	FASTA	128	14,958
	10 20 30 40 50 60 MFPGKVNPRM LKKMQKMMKD FGMETEDLDV RKVIFVFDDE EWVFEEPKVQ VMDILGVKTY 70 80 90 100 110 120 SITGKPKKIK KEKVEEEEEV KVEITEEDVE LVAKQCNVSK EEARKALEEC NGDIAEAILK LEEEKEEN

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98268.1.
PIR	A64335.
RefSeq	NP_247253.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57728.
ModBase	Search...
Protein-protein interaction databases
STRING	243232.MJ0280.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB98268; AAB98268; MJ_0280.
GeneID	1451135.
KEGG	mja:MJ_0280.
Phylogenomic databases
eggNOG	COG1308.
KO	K03626.
OMA	MKQMMKQ.
ProtClustDB	PRK06369.
Family and domain databases
HAMAP	MF_00814. NAC_arch.
InterPro	IPR005231. NAC_arc. IPR002715. Nas_poly-pep-assoc_cplx_dom. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Pfam	PF01849. NAC. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00264. TIGR00264. 1 hit.
PROSITE	PS51151. NAC_AB. 1 hit. PS50030. UBA. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NAC_METJA

Accession

Primary (citable) accession number: Q57728

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program