Q57724 (KORA_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2-oxoglutarate synthase subunit korA
EC=1.2.7.3

Alternative name(s):
2-ketoglutarate oxidoreductase alpha chain
Short name=KOR
2-oxoglutarate-ferredoxin oxidoreductase subunit alpha

Gene names

Name:	korA
Ordered Locus Names:	MJ0276

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-oxoglutarate + CoA + 2 oxidized ferredoxin = succinyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of the korA, korB, korC and korD subunits By similarity.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	2-oxoglutarate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 366	366	2-oxoglutarate synthase subunit korA		PRO_0000099938

Sequences

	Sequence		Length	Mass (Da)
	Q57724 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 7C5E41EAD9EB6E78	FASTA	366	41,060
	10 20 30 40 50 60 MKVEFMQGNQ ACAKGAIKAG CRFFAGYPIT PSTEIAEAMA RELPKVGGYY IQMEDEIGSI 70 80 90 100 110 120 AAVIGASWGG LKAMTATSGP GFSLMQENIG FAYMTETPCV VVDIQRGGPS TGQPTMASQG 130 140 150 160 170 180 DMMQCRWGSH GDYEVIALAP SSVQEMYDFT IMAFNYAEKY RIPVFVMADE IVGHMREKVI 190 200 210 220 230 240 LHDNIEIINR KKPEEKPCKK PYPFDKLIPE MPVFGEGYNV HITGLTHDER GYPDVSPETH 250 260 270 280 290 300 DKLVRRIVNK IRKNKDEIIK WEGENLDAEI VFVCYGSPSR TVKHAVRNLR EKGLDVGYIR 310 320 330 340 350 360 LITVYPFPDD LLKKLKAKKV VVPEMNLGQI YYEVERVCKK AEEVILVDKI GGELHRPEEL ERAVLG

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98264.1.
PIR	E64334.
RefSeq	NP_247249.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57724.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1451131.
GenomeReviews	Gene locus MJ0276 in contig L77117_GR.
KEGG	mja:MJ_0276.
NMPDR	fig|243232.1.peg.286.
TIGR	MJ0276.
Phylogenomic databases
HOGENOM	HBG399087.
OMA	TEKVVIP.
ProtClustDB	PRK08659.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0276-MONOMER.
Family and domain databases
InterPro	IPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N. IPR009014. Transketo_C/Pyr-ferredox_oxred. IPR015941. Transketolase-like_C. [Graphical view]
Gene3D	G3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KO	K00174.
Pfam	PF01855. POR_N. 1 hit. [Graphical view]
SUPFAM	SSF52922. Transketo_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KORA_METJA

Accession

Primary (citable) accession number: Q57724

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program