Q57715 (PORA_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyruvate synthase subunit porA
EC=1.2.7.1

Alternative name(s):
Pyruvate oxidoreductase alpha chain
Short name=POR
Pyruvic-ferredoxin oxidoreductase subunit alpha

Gene names

Name:	porA
Ordered Locus Names:	MJ0267

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain By similarity.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	pyruvate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	Pyruvate synthase subunit porA		PRO_0000099896

Sequences

	Sequence		Length	Mass (Da)
	Q57715 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 2CAA3DDE3EB0F5A9	FASTA	389	42,971
	10 20 30 40 50 60 METMCEVKVI TGTSAAAEAA KLADVDVIAA YPITPQTTCV EKLAEFVANG ELDAEYIKVE 70 80 90 100 110 120 SEHSAMSACI GAAATGARTF TATASQGLAL MHEMLFIASG MRLPIVMMVA NRALSAPINI 130 140 150 160 170 180 WNDHQDSIAE RDSGWIQIYV EDNQETLDSI IQAYKIAENE DVLLPVMVCL DGFILTHTVE 190 200 210 220 230 240 PVTIPKAERV REFLGVYEPK HAYLDPDRPI TQGPVGVPDC YMETRKQIEE AMERAKKVIR 250 260 270 280 290 300 DVNEEFAEWF KRKYGNGLVE AYNLDNADTV LVAMGSVCGT IKYVIDELKK EGKNVGLLRI 310 320 330 340 350 360 RAFRPFPKED VKELLKDANN IAVLDKNISL GFNKGALGIE MASILKNKKV CNYIVGLGGR 370 380 DIKIDDIKTI INHVEKAEDD STLWVGLKE

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98254.1.
PIR	D64333.
RefSeq	NP_247239.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57715.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1451121.
GenomeReviews	Gene locus MJ0267 in contig L77117_GR.
KEGG	mja:MJ_0267.
NMPDR	fig|243232.1.peg.276.
TIGR	MJ0267.
Phylogenomic databases
HOGENOM	HBG313202.
OMA	EIEVWDG.
ProtClustDB	CLSK876137.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0267-MONOMER.
Family and domain databases
InterPro	IPR002880. Pyrv_Fd/Flavodoxin_OxRdtase_N. IPR009014. Transketo_C/Pyr-ferredox_oxred. IPR015941. Transketolase-like_C. [Graphical view]
Gene3D	G3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KO	K00169.
Pfam	PF01855. POR_N. 1 hit. [Graphical view]
SUPFAM	SSF52922. Transketo_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PORA_METJA

Accession

Primary (citable) accession number: Q57715

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	November 16, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program