Q57714 (PORB_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyruvate synthase subunit porB
EC=1.2.7.1

Alternative name(s):
Pyruvate oxidoreductase beta chain
Short name=POR
Pyruvic-ferredoxin oxidoreductase subunit beta

Gene names

Name:	porB
Ordered Locus Names:	MJ0266

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain By similarity.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	pyruvate synthase activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Pyruvate synthase subunit porB		PRO_0000099903

Sequences

	Sequence		Length	Mass (Da)
	Q57714 [UniParc]. Last modified May 30, 2000. Version 3. Checksum: D772C50EE8611A49	FASTA	298	33,098
	10 20 30 40 50 60 MIVMQFPREE YFAPGHRGCA GCGAAIVARL LLKVAGKDTI ITNATGCLEV MTTPYPETSW 70 80 90 100 110 120 RVPWIHTAFE NAAATASGIE AAVKALKRKR GKFADKKINV IAIGGDGGTA DIGFQALSGA 130 140 150 160 170 180 MERGHDILYI MYDNEAYMNT GIQRSSSTPF MAATTTSPAG SKIRGEDRPK KDMTMIMAAH 190 200 210 220 230 240 GIPYVATACI SYPEDFMRKV KKALSIEGPK FIQVLQPCTT GWGYPPEKTI EIGRLAVETG 250 260 270 280 290 IFPLYEIENG EFRITYKPAK RKPVREYLKM QKRYRHLTDE DIERIQKYID EKCKLLGL

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98253.1.
PIR	C64333.
RefSeq	NP_247238.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57714.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1451120.
GenomeReviews	Gene locus MJ0266 in contig L77117_GR.
KEGG	mja:MJ_0266.
NMPDR	fig|243232.1.peg.275.
TIGR	MJ0266.
Phylogenomic databases
HOGENOM	HBG313203.
OMA	VATACIS.
ProtClustDB	PRK11865.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0266-MONOMER.
Family and domain databases
InterPro	IPR011766. TPP_enzyme-bd_C. [Graphical view]
KO	K00170.
Pfam	PF02775. TPP_enzyme_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PORB_METJA

Accession

Primary (citable) accession number: Q57714

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 30, 2000
Last modified:	November 16, 2011
This is version 64 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program