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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:MJ0247
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001491961 – 247DNA polymerase sliding clampAdd BLAST247

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi243232.MJ_0247

Structurei

3D structure databases

ProteinModelPortaliQ57697
SMRiQ57697
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
InParanoidiQ57697
KOiK04802
OMAiKCANSDD
OrthoDBiPOG093Z0814
PhylomeDBiQ57697

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
TIGRFAMsiTIGR00590 pcna, 1 hit
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q57697-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRGVMESAK EFKKVVDTIS TLLDEICFEV DEEGIKASAM DPSHVALVSL
60 70 80 90 100
EIPRLAFEEY EADSHDIGID LEAFKKVMNR AKAKDRLILE LDEEKNKLNV
110 120 130 140 150
IFENTGKRKF SLALLDISAS SVKVPEIEYP NVIMIKGDAF KEALKDADLF
160 170 180 190 200
SDYVILKADE DKFVIHAKGD LNENEAIFEK DSSAIISLEV KEEAKSAFNL
210 220 230 240
DYLMDMVKGV SSGDIIKIYL GNDMPLKLEY SIAGVNLTFL LAPRIEG
Length:247
Mass (Da):27,638
Last modified:November 1, 1996 - v1
Checksum:i28E8A363741931A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB98235.1
PIRiH64330

Genome annotation databases

EnsemblBacteriaiAAB98235; AAB98235; MJ_0247
KEGGimja:MJ_0247

Similar proteinsi

Entry informationi

Entry nameiPCNA_METJA
AccessioniPrimary (citable) accession number: Q57697
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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