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Q57692

- Y240_METJA

UniProt

Q57692 - Y240_METJA

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Protein
Putative adenylate cyclase MJ0240
Gene
MJ0240
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Could catalyze the biosynthesis of cyclic AMP (cAMP) from ATP By similarity.

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei37 – 371Proton acceptor By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. adenylate cyclase activity Source: UniProtKB
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    cAMP biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative adenylate cyclase MJ0240 (EC:4.6.1.1)
    Alternative name(s):
    ATP pyrophosphate-lyase
    Adenylyl cyclase
    Gene namesi
    Ordered Locus Names:MJ0240
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 175175Putative adenylate cyclase MJ0240
    PRO_0000106757Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ0240.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57692.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 175175CYTH
    Add
    BLAST

    Sequence similaritiesi

    Contains 1 CYTH domain.

    Phylogenomic databases

    eggNOGiCOG1437.
    KOiK05873.
    OMAiRETMCIV.
    PhylomeDBiQ57692.

    Family and domain databases

    Gene3Di2.40.320.10. 1 hit.
    InterProiIPR008173. Adenylyl_cyclase_CyaB.
    IPR023577. CYTH-like_domain.
    [Graphical view]
    PfamiPF01928. CYTH. 1 hit.
    [Graphical view]
    SUPFAMiSSF55154. SSF55154. 1 hit.
    TIGRFAMsiTIGR00318. cyaB. 1 hit.
    PROSITEiPS51707. CYTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57692-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIEVEIKVKI DDKNKVVEQL KKLGFKFIKK KFQEDIYFNG IDRDFRETDE    50
    ALRIRDEDGN FFVTYKGPKI DKISKTREEI EVKIEDKEKM RQIFKKLGFK 100
    EVPPIRKIRE IYKKEDIEAS IDDVEGLGLF LELEKSISDI NEKDKVLEEM 150
    MEILKALNIS KDNIIRKSYL ELRGL 175
    Length:175
    Mass (Da):20,821
    Last modified:November 1, 1996 - v1
    Checksum:i7A85A90FD46F97F9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98225.1.
    PIRiA64330.
    RefSeqiNP_247211.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB98225; AAB98225; MJ_0240.
    GeneIDi1451094.
    KEGGimja:MJ_0240.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB98225.1 .
    PIRi A64330.
    RefSeqi NP_247211.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q57692.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ0240.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB98225 ; AAB98225 ; MJ_0240 .
    GeneIDi 1451094.
    KEGGi mja:MJ_0240.

    Phylogenomic databases

    eggNOGi COG1437.
    KOi K05873.
    OMAi RETMCIV.
    PhylomeDBi Q57692.

    Family and domain databases

    Gene3Di 2.40.320.10. 1 hit.
    InterProi IPR008173. Adenylyl_cyclase_CyaB.
    IPR023577. CYTH-like_domain.
    [Graphical view ]
    Pfami PF01928. CYTH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55154. SSF55154. 1 hit.
    TIGRFAMsi TIGR00318. cyaB. 1 hit.
    PROSITEi PS51707. CYTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiY240_METJA
    AccessioniPrimary (citable) accession number: Q57692
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: July 9, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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