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Q57692 (Y240_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative adenylate cyclase MJ0240

EC=4.6.1.1
Alternative name(s):
ATP pyrophosphate-lyase
Adenylyl cyclase
Gene names
Ordered Locus Names:MJ0240
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length175 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Could catalyze the biosynthesis of cyclic AMP (cAMP) from ATP By similarity.

Catalytic activity

ATP = 3',5'-cyclic AMP + diphosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the adenylyl cyclase CyaB family.

Contains 1 CYTH domain.

Ontologies

Keywords
   Biological processcAMP biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

adenylate cyclase activity

Inferred from sequence or structural similarity. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 175175Putative adenylate cyclase MJ0240
PRO_0000106757

Regions

Domain1 – 175175CYTH

Sites

Active site371Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57692 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7A85A90FD46F97F9

FASTA17520,821
        10         20         30         40         50         60 
MIEVEIKVKI DDKNKVVEQL KKLGFKFIKK KFQEDIYFNG IDRDFRETDE ALRIRDEDGN 

        70         80         90        100        110        120 
FFVTYKGPKI DKISKTREEI EVKIEDKEKM RQIFKKLGFK EVPPIRKIRE IYKKEDIEAS 

       130        140        150        160        170 
IDDVEGLGLF LELEKSISDI NEKDKVLEEM MEILKALNIS KDNIIRKSYL ELRGL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98225.1.
PIRA64330.
RefSeqNP_247211.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ57692.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0240.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98225; AAB98225; MJ_0240.
GeneID1451094.
KEGGmja:MJ_0240.

Phylogenomic databases

eggNOGCOG1437.
KOK05873.
OMARETMCIV.
PhylomeDBQ57692.

Family and domain databases

Gene3D2.40.320.10. 1 hit.
InterProIPR008173. Adenylyl_cyclase_CyaB.
IPR023577. CYTH-like_domain.
[Graphical view]
PfamPF01928. CYTH. 1 hit.
[Graphical view]
SUPFAMSSF55154. SSF55154. 1 hit.
TIGRFAMsTIGR00318. cyaB. 1 hit.
PROSITEPS51707. CYTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY240_METJA
AccessionPrimary (citable) accession number: Q57692
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names