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Protein

Putative adenylate cyclase MJ0240

Gene

MJ0240

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Could catalyze the biosynthesis of cyclic AMP (cAMP) from ATP.By similarity

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei37Proton acceptorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionLyase
Biological processcAMP biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adenylate cyclase MJ0240 (EC:4.6.1.1)
Alternative name(s):
ATP pyrophosphate-lyase
Adenylyl cyclase
Gene namesi
Ordered Locus Names:MJ0240
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001067571 – 175Putative adenylate cyclase MJ0240Add BLAST175

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ_0240.

Structurei

3D structure databases

ProteinModelPortaliQ57692.
SMRiQ57692.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 175CYTHPROSITE-ProRule annotationAdd BLAST175

Sequence similaritiesi

Belongs to the adenylyl cyclase CyaB family.Curated

Phylogenomic databases

eggNOGiarCOG01723. Archaea.
COG1437. LUCA.
InParanoidiQ57692.
KOiK05873.
OMAiQHPCRDF.
OrthoDBiPOG093Z0C4I.
PhylomeDBiQ57692.

Family and domain databases

CDDicd07890. CYTH-like_AC_IV-like. 1 hit.
InterProiView protein in InterPro
IPR008173. Adenylyl_cyclase_CyaB.
IPR033469. CYTH-like_dom_sf.
IPR023577. CYTH_domain.
PANTHERiPTHR21028. PTHR21028. 1 hit.
PfamiView protein in Pfam
PF01928. CYTH. 1 hit.
SMARTiView protein in SMART
SM01118. CYTH. 1 hit.
SUPFAMiSSF55154. SSF55154. 1 hit.
TIGRFAMsiTIGR00318. cyaB. 1 hit.
PROSITEiView protein in PROSITE
PS51707. CYTH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57692-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEVEIKVKI DDKNKVVEQL KKLGFKFIKK KFQEDIYFNG IDRDFRETDE
60 70 80 90 100
ALRIRDEDGN FFVTYKGPKI DKISKTREEI EVKIEDKEKM RQIFKKLGFK
110 120 130 140 150
EVPPIRKIRE IYKKEDIEAS IDDVEGLGLF LELEKSISDI NEKDKVLEEM
160 170
MEILKALNIS KDNIIRKSYL ELRGL
Length:175
Mass (Da):20,821
Last modified:November 1, 1996 - v1
Checksum:i7A85A90FD46F97F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98225.1.
PIRiA64330.
RefSeqiWP_010869738.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98225; AAB98225; MJ_0240.
GeneIDi1451094.
KEGGimja:MJ_0240.

Similar proteinsi

Entry informationi

Entry nameiY240_METJA
AccessioniPrimary (citable) accession number: Q57692
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families