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Q57689 (SYR_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:MJ0237
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length566 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 566566Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151646

Regions

Motif124 – 13411"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q57689 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: E02A48181481D655

FASTA56664,979
        10         20         30         40         50         60 
MDIKSNIINA LKEVISKEIC KEIDIKLDKT PNLELGDYSV NICFRLAKEL KKNPKIIAEE 

        70         80         90        100        110        120 
LVDKLKAMNI EGVKEIKAVN GYINFYIDYN KFAKNLMEEI DKKGNNYGRG DKKSIKIILE 

       130        140        150        160        170        180 
HTSANPNGPL HIGHLRNAII GDCLKRILEF YGYDVETHYY VNDMGRQMAL VVYGIELFGL 

       190        200        210        220        230        240 
DKEKKKDHAI AETYVKINKY LEEHPEEEEK ILELMRKYED ALENNEDNEI TKKFEFAVNY 

       250        260        270        280        290        300 
ALDGIKETLK NLNIKHDTFV WESSYVRNGM VKKVIEKLME TGKVIKEETY MLDLSDFGIE 

       310        320        330        340        350        360 
KKMVLARANG TSLYSTRDIA YHLDKLSKCD IGIDVLGADH KLTAEMVKAA LKLLGSKVPE 

       370        380        390        400        410        420 
VIFYEFISLP EGSMSTRRGR FISTDELLEE AIKRAKEECN KRGVEENIAY DIGLGAVRYN 

       430        440        450        460        470        480 
IARISPEKPM VFRWEEALDF EKVGCPFIQY AHARCCSILK EAENKGVKDE AVFNYELTSE 

       490        500        510        520        530        540 
EKELIKMLDE FKDIIKESAE SRRVHILANY LLELAKAFNR FYANCPILMT KVDDDVKKSR 

       550        560 
LKLVKSTKTV LETGLELLGI NCPGRM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98223.1.
PIRF64329.
RefSeqNP_247208.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ57689.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0237.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98223; AAB98223; MJ_0237.
GeneID1451091.
KEGGmja:MJ_0237.

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAMEHMGFG.
PhylomeDBQ57689.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_METJA
AccessionPrimary (citable) accession number: Q57689
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries