Q57674 (ATPL_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable ATPase proteolipid chain

Gene names

Ordered Locus Names:

MJ0221

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the V-ATPase proteolipid subunit family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Lipid-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting V-type ATPase, V0 domain Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hydrogen ion transmembrane transporter activity Inferred from electronic annotation. Source: InterPro hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Probable ATPase proteolipid chain		PRO_0000071731
Regions
	Transmembrane	5 – 25	21	Helical; Potential
	Transmembrane	63 – 83	21	Helical; Potential
	Transmembrane	90 – 110	21	Helical; Potential
	Transmembrane	125 – 145	21	Helical; Potential
	Transmembrane	155 – 175	21	Helical; Potential
	Transmembrane	195 – 215	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q57674 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 72DA35D2448BEAE6	FASTA	220	21,332
	10 20 30 40 50 60 MVDPLILGAV GAGLAVGIAG LGSGIGAGIT GASGAGVVAE DPNKFGTAIV FQALPQTQGL 70 80 90 100 110 120 YGFLVAILIL FVFKTVSPWA MFAAGLAAGL AGLSAIGQGI AASAGLGAVA EDNSIFGKAM 130 140 150 160 170 180 VFSVLPETQA IYGLLIAILL LVGVFKGNAG AETVAALGAG FAVGFAGLSG IGQGITAAGA 190 200 210 220 IGATARDPDA MGKGLVLAVM PETFAIFGLL IAILIMLMIK

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98207.1.
PIR	F64327.
RefSeq	NP_247190.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57674.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1451071.
GenomeReviews	Gene locus MJ0221 in contig L77117_GR.
KEGG	mja:MJ_0221.
NMPDR	fig|243232.1.peg.227.
TIGR	MJ0221.
Phylogenomic databases
HOGENOM	HBG465267.
OMA	MENITLM.
ProtClustDB	PRK06271.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0221-MONOMER.
Family and domain databases
InterPro	IPR002379. ATPase_F0/V0-cplx_csu. IPR000245. ATPase_V0-cplx_csu. [Graphical view]
Gene3D	G3DSA:1.20.20.10. ATPase_F0/V0_c. 3 hits.
KO	K02124.
Pfam	PF00137. ATP-synt_C. 3 hits. [Graphical view]
PRINTS	PR00122. VACATPASE.
SUPFAM	SSF81333. ATPase_F0/V0_c. 3 hits.
ProtoNet	Search...

Entry information

Entry name

ATPL_METJA

Accession

Primary (citable) accession number: Q57674

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program