Q57650 (RPOK_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit K
EC=2.7.7.6

Gene names

Name:	rpoK
Ordered Locus Names:	MJ0197

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length	57 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00192
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00192
Sequence similarities	Belongs to the archaeal rpoK/eukaryotic RPB6 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 57	57	DNA-directed RNA polymerase subunit K HAMAP MF_00192		PRO_0000133813

Sequences

	Sequence		Length	Mass (Da)
	Q57650 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 46F97B2F02416C77	FASTA	57	6,292
	10 20 30 40 50 MKLTKFEIAR ILGARSLQIS SGAYATIETK CDSSLKIAYE EIKQGKVPLK PIRPVKA

References

[1]

"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98177.1.
PIR	F64324.
RefSeq	NP_247165.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57650.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1451046.
GenomeReviews	Gene locus MJ0197 in contig L77117_GR.
KEGG	mja:MJ_0197.
NMPDR	fig|243232.1.peg.202.
TIGR	MJ0197.
Phylogenomic databases
HOGENOM	HBG646526.
OMA	SLQISDG.
ProtClustDB	PRK01099.
Enzyme and pathway databases
BioCyc	MJAN243232:MJ_0197-MONOMER.
Family and domain databases
HAMAP	MF_00192. RNApol_arch_K. [Tree]
InterPro	IPR020708. DNA-dir_RNA_polK_14-18kDa_CS. IPR006111. DNA-dir_RNA_polK_K/RPABC2. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Gene3D	G3DSA:3.90.940.10. RNAP_RPB6_omega. 1 hit.
KO	K03055.
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
PIRSF	PIRSF000778. RpoK/RPB6. 1 hit.
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
PROSITE	PS01111. RNA_POL_K_14KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPOK_METJA

Accession

Primary (citable) accession number: Q57650

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 16, 2011
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program