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Q57634 (MSMJS_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Small-conductance mechanosensitive channel MscMJ
Gene names
Ordered Locus Names:MJ0170
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length350 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Small-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Exhibits a sixfold preference for cations over anions. Non-rectifying. Ref.2

Subcellular location

Cell membrane; Multi-pass membrane protein Ref.2.

Sequence similarities

Belongs to the MscS (TC 1.A.23) family. [View classification]

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionIon channel
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_procession transport

Inferred from electronic annotation. Source: UniProtKB-KW

transmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 350350Small-conductance mechanosensitive channel MscMJ
PRO_0000110253

Regions

Transmembrane10 – 3021Helical; Potential
Transmembrane59 – 7921Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane130 – 15021Helical; Potential
Transmembrane154 – 17421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q57634 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4EA0E5025086E7DF

FASTA35039,953
        10         20         30         40         50         60 
MNMEIFGNSI SNILIFVVIT LLGIFIGKIV DKIVRNYLKK IIDKTKTKFD DIILESIDLP 

        70         80         90        100        110        120 
IIVLVVTLFF YFGLRFLILP DYILKLIDEA VKVVVILSAT YFAVKFIDGI FEHYLIPLTE 

       130        140        150        160        170        180 
KTETELDEHI IKPLKKVVKI LTILLGILTA LSSVGYDITA LLAGLGVGGL ALALAMQDTI 

       190        200        210        220        230        240 
KNFIAGILIL IDKPFSLGHW VKVKGAEGIV EEIGIRSTRI RTFDYTLITI PNSELLDSAI 

       250        260        270        280        290        300 
ENLTVRDRRR VLMTIGLTYN TPVEKIKRAK EIIKEIVENH PATLPPYRVH FREYGDWSLN 

       310        320        330        340        350 
LRVEYFVRNM GFDYYLNAVD EINLKIKEEF EKEGIEMAFP TYTVYLEKDN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98155.1.
PIRC64321.
RefSeqNP_247138.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ57634.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0170.

Protein family/group databases

TCDB1.A.23.4.2. the small conductance mechanosensitive ion channel (mscs) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98155; AAB98155; MJ_0170.
GeneID1451017.
KEGGmja:MJ_0170.

Phylogenomic databases

eggNOGCOG0668.
KOK16052.
OMADLRVEYF.
ProtClustDBCLSK876099.

Family and domain databases

InterProIPR010920. LSM_dom.
IPR011066. MscC_channel_C.
IPR006685. MscS_channel.
IPR006686. MscS_channel_CS.
IPR011014. MscS_channel_TM-2.
[Graphical view]
PfamPF00924. MS_channel. 1 hit.
[Graphical view]
SUPFAMSSF50182. SSF50182. 1 hit.
SSF82689. SSF82689. 1 hit.
SSF82861. SSF82861. 1 hit.
PROSITEPS01246. UPF0003. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMSMJS_METJA
AccessionPrimary (citable) accession number: Q57634
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names