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Q57572 (KPYK_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length447 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor

Magnesium By similarity.

Potassium By similarity.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the pyruvate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 447447Pyruvate kinase
PRO_0000112128

Sites

Metal binding351Potassium By similarity
Metal binding371Potassium By similarity
Metal binding611Potassium By similarity
Metal binding2031Magnesium By similarity
Metal binding2271Magnesium By similarity
Binding site331Substrate By similarity
Binding site2261Substrate; via amide nitrogen By similarity
Binding site2271Substrate; via amide nitrogen By similarity
Binding site2591Substrate By similarity
Site2011Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57572 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: EA6C4DC031B8C1A4

FASTA44750,490
        10         20         30         40         50         60 
MVGMMRKTKI LVTLGPSLEN KLDKAINLID GVRFNMSHAT TDYCEKFLNI LEKNNIAKVM 

        70         80         90        100        110        120 
DLKGIKIRIK EVKLKNKILK MGEKVVIGED IKLNYNIDTI EEGHFILIND GKIKLRVVEK 

       130        140        150        160        170        180 
TDKIIAVVEV GGEIKEGMGV NLPDTRIELP IIDETDLKNI KFAVEKDFEY IALSFVRNKE 

       190        200        210        220        230        240 
DVKELKDIIS EYKGDCEVIS KIETKEGLKN IKEIARESDG VMVARGDLGV EVPIENIPIE 

       250        260        270        280        290        300 
QKNILRIANR YGILSITATQ ILDSMINNPF PTRAEVTDIA NAIYDGTDCL MLSNETTIGK 

       310        320        330        340        350        360 
YPIEAIKVLN KVAKVADEHY EEFGDRVCLE VESIDEGLVY AVYELYKKLN TKLVITPTYS 

       370        380        390        400        410        420 
GRTAKLISKL RINSKIIAPT PNIRTLKRLR LVWGVESCLM EEFDDMEKII NTCREMAKKE 

       430        440 
IGKGIYLITL GHPIGQKKTN TIKVESI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB98090.1.
PIRD64313.
RefSeqNP_247072.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ57572.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ0108.

Proteomic databases

PRIDEQ57572.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB98090; AAB98090; MJ_0108.
GeneID1450949.
KEGGmja:MJ_0108.

Phylogenomic databases

eggNOGCOG0469.
KOK00873.
OMATPTYSGR.
PhylomeDBQ57572.

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Family and domain databases

Gene3D2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
SUPFAMSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPYK_METJA
AccessionPrimary (citable) accession number: Q57572
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names