Q57571 (Y107_METJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein MJ0107

Gene names

Ordered Locus Names:

MJ0107

Organism

Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]

Taxonomic identifier

243232 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › Methanocaldococcus jannaschii

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function	Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6-hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4-aminobenzoate to form 7,8-dihydropteroate.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Contains 1 pterin-binding domain.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	pteridine-containing compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 525	525	Uncharacterized protein MJ0107		PRO_0000106696
Regions
	Transmembrane	28 – 48	21	Helical; Potential
	Transmembrane	353 – 373	21	Helical; Potential
	Domain	146 – 394	249	Pterin-binding

Sequences

	Sequence		Length	Mass (Da)
	Q57571 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: AA8BA61C6B81863D	FASTA	525	59,645
	10 20 30 40 50 60 MREIMKILII TGKLAERKVK DAVKKYDFID VHVANISVAA FLTPNLIIKE IKKLENKLGK 70 80 90 100 110 120 KLKDIYDFVL VTGLIRHDLK NVEEETGIKC FKSTREASDI PILIENLDKI KLSTKEYADL 130 140 150 160 170 180 QLLEIIRKKC EEEIKKAEEQ ELGEGDIKIG KLKVGDKFPM RVLGEIVHAP WLKEKELEEK 190 200 210 220 230 240 IIYYLESGAD MIDLGMVSNE NNADKIKDML KIARDLTDNP ISVDTLNTKE LIEAINLGAD 250 260 270 280 290 300 MILSVDAGNL DELIPYLKDS ETAVVVLPTN YKTNYVPETI EGKIKSLEEN IKKLIDAGIE 310 320 330 340 350 360 KIVADPILEP INNAGCSFIE SVIACREFKK RNKLPLFFGV GNVTELFDAD SNGVNALLAA 370 380 390 400 410 420 IGAEIGANIL FTPEASAKCK FSIKELKIAS KMMFLAKKRN SLPKDIGYNL INYKDKRFEE 430 440 450 460 470 480 EITFNSYNIP IIKAEEDERQ ILDEGSFKIE IDRKNKEIVA IYFNKRREPV LIIRGKKPKE 490 500 510 520 IYETAIRLNL IKKLDHASYF GRELAKAEIA LRIGKKYNQD FDLFL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. , Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C. Science 273:1058-1073(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
[2]	"Identifying two ancient enzymes in Archaea using predicted secondary structure alignment." Xu H., Aurora R., Rose G.D., White R.H. Nat. Struct. Biol. 6:750-754(1999) [PubMed] [Europe PMC] [Abstract] Cited for: LACK OF DHPS ACTIVITY. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L77117 Genomic DNA. Translation: AAB98089.1.
PIR	C64313.
RefSeq	NP_247071.1. NC_000909.1.
3D structure databases
ProteinModelPortal	Q57571.
ModBase	Search...
Protein-protein interaction databases
STRING	243232.MJ0107.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB98089; AAB98089; MJ_0107.
GeneID	1450948.
KEGG	mja:MJ_0107.
Phylogenomic databases
eggNOG	COG0294.
OMA	VLIPTNQ.
ProtClustDB	CLSK876073.
Family and domain databases
Gene3D	3.20.20.20. 2 hits.
InterPro	IPR005236. Dihydropt_synth. IPR011005. Dihydropteroate_synth-like. IPR025595. DUF4346. IPR000489. Pterin-binding. [Graphical view]
Pfam	PF14251. DUF4346. 1 hit. PF00809. Pterin_bind. 1 hit. [Graphical view]
SUPFAM	SSF51717. DHP_synth_like. 1 hit.
TIGRFAMs	TIGR00284. TIGR00284. 1 hit.
PROSITE	PS50972. PTERIN_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y107_METJA

Accession

Primary (citable) accession number: Q57571

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program