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Protein
Submitted name:

Penicillin binding protein 4

Gene

pdp4

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei125Sulfate 1; via amide nitrogenCombined sources1
Binding sitei193Sulfate 2Combined sources1

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiS11.010.

Names & Taxonomyi

Protein namesi
Submitted name:
Penicillin binding protein 4Imported
Gene namesi
Name:pdp4Imported
Synonyms:pgp4Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei402 – 423HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500878087625 – 431Sequence analysisAdd BLAST407

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL0699.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TVFX-ray2.00A/B26-383[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 288Peptidase_S11InterPro annotationAdd BLAST233
Domaini317 – 382DUF1958InterPro annotationAdd BLAST66

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni155 – 156Sulfate 2 bindingCombined sources2
Regioni199 – 200Sulfate 3 bindingCombined sources2

Sequence similaritiesi

Belongs to the peptidase S11 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105DZ1. Bacteria.
COG1686. LUCA.

Family and domain databases

Gene3Di2.30.140.20. 1 hit.
3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015294. Pen-bd_prot4_C_dom.
IPR015956. Peniciliin-bd_prot-assoc.
IPR018044. Peptidase_S11.
IPR001967. Peptidase_S11_N.
[Graphical view]
PfamiPF09211. DUF1958. 1 hit.
PF00768. Peptidase_S11. 1 hit.
[Graphical view]
PRINTSiPR00725. DADACBPTASE1.
SUPFAMiSSF56601. SSF56601. 1 hit.
SSF69189. SSF69189. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57540-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNLISIIII LCLTLSIMTP YAQAANSDVT PVQAANQYGY AGLSAAYEPT
60 70 80 90 100
SAVNVSQTGQ LLYQYNIDTK WNPASMTKLM TMYLTLEAVN KGQLSLDDTV
110 120 130 140 150
TMTNKEYIMS TLPELSNTKL YPGQVWTIAD LLQITVSNSS NAAALILAKK
160 170 180 190 200
VSKNTSDFVD LMNNKAKAIG MKNTHFVNPT GAENSRLRTF APTKYKDQER
210 220 230 240 250
TVTTARDYAI LDLHVIKETP KILDFTKQLA PTTHAVTYYT FNFSLEGAKM
260 270 280 290 300
SLPGTDGLKT GSSDTANYNH TITTKRGKFR INQVIMGAGD YKNLGGEKQR
310 320 330 340 350
NMMGNALMER SFDQYKYVKI LSKGEQRING KKYYVENDLY DVLPSDFSKK
360 370 380 390 400
DYKLVVEDGK VHADYPREFI NKDYRPPTVE VHQPIIQKAN TVAKSMWEEH
410 420 430
PLFTIIGGAC LVAGLALIVH MIINRLFRKR K
Length:431
Mass (Da):48,301
Last modified:November 1, 1996 - v1
Checksum:i8978E69B1BC33784
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87104 Genomic DNA. Translation: CAA60582.1.
X87105 Genomic DNA. Translation: CAA60585.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87104 Genomic DNA. Translation: CAA60582.1.
X87105 Genomic DNA. Translation: CAA60585.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TVFX-ray2.00A/B26-383[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93062.SACOL0699.

Protein family/group databases

MEROPSiS11.010.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105DZ1. Bacteria.
COG1686. LUCA.

Family and domain databases

Gene3Di2.30.140.20. 1 hit.
3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015294. Pen-bd_prot4_C_dom.
IPR015956. Peniciliin-bd_prot-assoc.
IPR018044. Peptidase_S11.
IPR001967. Peptidase_S11_N.
[Graphical view]
PfamiPF09211. DUF1958. 1 hit.
PF00768. Peptidase_S11. 1 hit.
[Graphical view]
PRINTSiPR00725. DADACBPTASE1.
SUPFAMiSSF56601. SSF56601. 1 hit.
SSF69189. SSF69189. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ57540_STAAU
AccessioniPrimary (citable) accession number: Q57540
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.