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Protein
Submitted name:

Penicillin binding protein 4

Gene

pdp4

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei125 – 1251Sulfate 1; via amide nitrogenCombined sources
Binding sitei193 – 1931Sulfate 2Combined sources

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

MEROPSiS11.010.

Names & Taxonomyi

Protein namesi
Submitted name:
Penicillin binding protein 4Imported
Gene namesi
Name:pdp4Imported
Synonyms:pgp4Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei402 – 42322HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 431407Sequence analysisPRO_5007704465Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL0699.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TVFX-ray2.00A/B26-383[»]
SMRiQ57540. Positions 19-383.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 288233Peptidase_S11InterPro annotationAdd
BLAST
Domaini317 – 38266DUF1958InterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni155 – 1562Sulfate 2 bindingCombined sources
Regioni199 – 2002Sulfate 3 bindingCombined sources

Sequence similaritiesi

Belongs to the peptidase S11 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105DZ1. Bacteria.
COG1686. LUCA.

Family and domain databases

Gene3Di2.30.140.20. 1 hit.
3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015294. Pen-bd_prot4_C_dom.
IPR015956. Peniciliin-bd_prot-assoc.
IPR018044. Peptidase_S11.
IPR001967. Peptidase_S11_N.
[Graphical view]
PfamiPF09211. DUF1958. 1 hit.
PF00768. Peptidase_S11. 1 hit.
[Graphical view]
PRINTSiPR00725. DADACBPTASE1.
SUPFAMiSSF56601. SSF56601. 1 hit.
SSF69189. SSF69189. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57540-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNLISIIII LCLTLSIMTP YAQAANSDVT PVQAANQYGY AGLSAAYEPT
60 70 80 90 100
SAVNVSQTGQ LLYQYNIDTK WNPASMTKLM TMYLTLEAVN KGQLSLDDTV
110 120 130 140 150
TMTNKEYIMS TLPELSNTKL YPGQVWTIAD LLQITVSNSS NAAALILAKK
160 170 180 190 200
VSKNTSDFVD LMNNKAKAIG MKNTHFVNPT GAENSRLRTF APTKYKDQER
210 220 230 240 250
TVTTARDYAI LDLHVIKETP KILDFTKQLA PTTHAVTYYT FNFSLEGAKM
260 270 280 290 300
SLPGTDGLKT GSSDTANYNH TITTKRGKFR INQVIMGAGD YKNLGGEKQR
310 320 330 340 350
NMMGNALMER SFDQYKYVKI LSKGEQRING KKYYVENDLY DVLPSDFSKK
360 370 380 390 400
DYKLVVEDGK VHADYPREFI NKDYRPPTVE VHQPIIQKAN TVAKSMWEEH
410 420 430
PLFTIIGGAC LVAGLALIVH MIINRLFRKR K
Length:431
Mass (Da):48,301
Last modified:November 1, 1996 - v1
Checksum:i8978E69B1BC33784
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87104 Genomic DNA. Translation: CAA60582.1.
X87105 Genomic DNA. Translation: CAA60585.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87104 Genomic DNA. Translation: CAA60582.1.
X87105 Genomic DNA. Translation: CAA60585.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TVFX-ray2.00A/B26-383[»]
SMRiQ57540. Positions 19-383.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93062.SACOL0699.

Protein family/group databases

MEROPSiS11.010.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105DZ1. Bacteria.
COG1686. LUCA.

Family and domain databases

Gene3Di2.30.140.20. 1 hit.
3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015294. Pen-bd_prot4_C_dom.
IPR015956. Peniciliin-bd_prot-assoc.
IPR018044. Peptidase_S11.
IPR001967. Peptidase_S11_N.
[Graphical view]
PfamiPF09211. DUF1958. 1 hit.
PF00768. Peptidase_S11. 1 hit.
[Graphical view]
PRINTSiPR00725. DADACBPTASE1.
SUPFAMiSSF56601. SSF56601. 1 hit.
SSF69189. SSF69189. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ57540_STAAU
AccessioniPrimary (citable) accession number: Q57540
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.