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Protein

Translocation and assembly module TamB

Gene

tamB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Translocation and assembly module TamB
Alternative name(s):
Autotransporter assembly factor TamB
Gene namesi
Name:tamB
Ordered Locus Names:HI_0696
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2727CytoplasmicBy similarityAdd
BLAST
Transmembranei28 – 4821Helical; Signal-anchor for type II membrane proteinBy similarityAdd
BLAST
Topological domaini49 – 12981250PeriplasmicBy similarityAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12981298Translocation and assembly module TamBPRO_0000169831Add
BLAST

Interactioni

Subunit structurei

Interacts with TamA.By similarity

Protein-protein interaction databases

STRINGi71421.HI0696.

Family & Domainsi

Sequence similaritiesi

Belongs to the TamB family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2911.
KOiK09800.
OMAiRDINAWR.
OrthoDBiEOG6GJBQK.
PhylomeDBiQ57523.

Family and domain databases

InterProiIPR007452. DUF490.
[Graphical view]
PfamiPF04357. DUF490. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57523-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEQIQPSET SPKSPEKPNK KHWVRKAVCI GSAVILVPVL GVAGALSFDA
60 70 80 90 100
GQKSLIQLVD KMLDSFSVEQ VEGGLQNGLV LKNVRYQTAG IETHIAQARL
110 120 130 140 150
QLDFGCLFSR EVCLRDFTLN KPTIAINTAL LPPSAPDNSK SGSMKRISLP
160 170 180 190 200
ISINAENLVM QDLSVNIDQT SITLGNFKSA VSLNNEKGLT IAPTEINDIS
210 220 230 240 250
VIAKKLSEVK SEPKAEQPNK PVDWAAIEQS LTPAFLGNVS EIILPFDLHI
260 270 280 290 300
PEISGKNWQY QAVNEKGETL QSVEMSSLIA QADTVDNQLQ LQKLAVESSL
310 320 330 340 350
GNLSSQGKLQ LDGDMPLDLT LKSHLEPLKS DGKEILPASD VDLTLSGSLK
360 370 380 390 400
KSTALSLKTK GVLDAELNGN VQLAQDKMPL NLTLNVAKGQ YTFVNTMTPL
410 420 430 440 450
KINDVTLKLT GDLLNYHAEL KGDVAGMNYI PASQVELNAD GKLYEVTVNK
460 470 480 490 500
LGIDSLDGKS EFVGNANWKN GANWDIQADL EKMNIAFFVP VMPATLSGKL
510 520 530 540 550
HSRGFAGSQG WQVEVPVADL NGMLSAKPIS LKGSATLNQN VLLTVPDLQI
560 570 580 590 600
KYGENYLKAS GVLDDHSDFA LDINAPNLRG LWSDLKGRVK GRVAISGQIT
610 620 630 640 650
TPNLDLDLTS SNLHLQGFQL AKASIKGHIN NASLSSGKLN IKAEQLHYGG
660 670 680 690 700
NIKLHLLDLD LSGDEQNHKL ILKSQGEPVA ANLQINGHFD RTLEQWKGTI
710 720 730 740 750
SQVKFETPIG DVKSNQAIAV SYDNKQTQAN IASHCWQNTD VELCFPQAFN
760 770 780 790 800
AGKQGNIPFQ FKRVNLDLVN KLIEQNSLKG NLQVQGNVAW FTDKPFQFTA
810 820 830 840 850
NVDGNHLAFS QKLDYRTFKL YIPKLTLNAD IQNNNLVLKT DINVHNQGRI
860 870 880 890 900
VGDIHLNDLA KNRQLGGTLA IERLNLSIAN QLLTSGESVN GEVVSKLSFG
910 920 930 940 950
GNLEKPLLNG DFNIRNIRTK LKSMPVNITD GDIALRFNDN RSTLQGKIKT
960 970 980 990 1000
VDSHLNLTGR ANWANIEHWT TELNAQANNF NVDIPSMAKL RFSPNITIKA
1010 1020 1030 1040 1050
NPKELNLSGT VDIPWARIKI DSLPDTAEPV SEDEVILNGP HKSKEELIKR
1060 1070 1080 1090 1100
EFAAKTKSGM EIRSDLRINI GKDVSLDAYG LKTNLDGLLS VKQDKGNLGL
1110 1120 1130 1140 1150
FGQINLTKGR YASFGQDLLI RKGLISFSGQ ATQPTLNIEA IRNPETMEDS
1160 1170 1180 1190 1200
KITAGVRVIG IADSPEVTIF SEPSKPQDQA LSYLLTGRSL ESSGEVGSTG
1210 1220 1230 1240 1250
SVGAALIGLG ISKSGKLVGS IGEVFGIQDL NLGTSGVGDK SKVTVSGNIT
1260 1270 1280 1290
NRLQIKYGVG LFDGLAEVTL RYRLMPQLYF QSVSSTNQVF DLLYKFEF
Length:1,298
Mass (Da):141,223
Last modified:October 31, 1996 - v1
Checksum:i2D905D8E6D9329E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22356.1.
PIRiA64157.
RefSeqiNP_438856.1. NC_000907.1.
WP_005694581.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22356; AAC22356; HI_0696.
GeneIDi950032.
KEGGihin:HI0696.
PATRICi20190013. VBIHaeInf48452_0728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22356.1.
PIRiA64157.
RefSeqiNP_438856.1. NC_000907.1.
WP_005694581.1. NC_000907.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0696.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22356; AAC22356; HI_0696.
GeneIDi950032.
KEGGihin:HI0696.
PATRICi20190013. VBIHaeInf48452_0728.

Phylogenomic databases

eggNOGiCOG2911.
KOiK09800.
OMAiRDINAWR.
OrthoDBiEOG6GJBQK.
PhylomeDBiQ57523.

Family and domain databases

InterProiIPR007452. DUF490.
[Graphical view]
PfamiPF04357. DUF490. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
  2. "Two-dimensional map of the proteome of Haemophilus influenzae."
    Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C., Fountoulakis M.
    Electrophoresis 21:411-429(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiTAMB_HAEIN
AccessioniPrimary (citable) accession number: Q57523
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1997
Last sequence update: October 31, 1996
Last modified: March 31, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.