Q57523 (TAMB_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translocation and assembly module TamB

Alternative name(s):
Autotransporter assembly factor TamB

Gene names

Name:	tamB
Ordered Locus Names:	HI_0696

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	1298 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane By similarity.
Subunit structure	Interacts with TamA By similarity.
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the TamB family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1298	1298	Translocation and assembly module TamB		PRO_0000169831
Regions
	Topological domain	1 – 27	27	Cytoplasmic By similarity
	Transmembrane	28 – 48	21	Helical; Signal-anchor for type II membrane protein; By similarity
	Topological domain	49 – 1298	1250	Periplasmic By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q57523 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 2D905D8E6D9329E9	FASTA	1,298	141,223
	10 20 30 40 50 60 MTEQIQPSET SPKSPEKPNK KHWVRKAVCI GSAVILVPVL GVAGALSFDA GQKSLIQLVD 70 80 90 100 110 120 KMLDSFSVEQ VEGGLQNGLV LKNVRYQTAG IETHIAQARL QLDFGCLFSR EVCLRDFTLN 130 140 150 160 170 180 KPTIAINTAL LPPSAPDNSK SGSMKRISLP ISINAENLVM QDLSVNIDQT SITLGNFKSA 190 200 210 220 230 240 VSLNNEKGLT IAPTEINDIS VIAKKLSEVK SEPKAEQPNK PVDWAAIEQS LTPAFLGNVS 250 260 270 280 290 300 EIILPFDLHI PEISGKNWQY QAVNEKGETL QSVEMSSLIA QADTVDNQLQ LQKLAVESSL 310 320 330 340 350 360 GNLSSQGKLQ LDGDMPLDLT LKSHLEPLKS DGKEILPASD VDLTLSGSLK KSTALSLKTK 370 380 390 400 410 420 GVLDAELNGN VQLAQDKMPL NLTLNVAKGQ YTFVNTMTPL KINDVTLKLT GDLLNYHAEL 430 440 450 460 470 480 KGDVAGMNYI PASQVELNAD GKLYEVTVNK LGIDSLDGKS EFVGNANWKN GANWDIQADL 490 500 510 520 530 540 EKMNIAFFVP VMPATLSGKL HSRGFAGSQG WQVEVPVADL NGMLSAKPIS LKGSATLNQN 550 560 570 580 590 600 VLLTVPDLQI KYGENYLKAS GVLDDHSDFA LDINAPNLRG LWSDLKGRVK GRVAISGQIT 610 620 630 640 650 660 TPNLDLDLTS SNLHLQGFQL AKASIKGHIN NASLSSGKLN IKAEQLHYGG NIKLHLLDLD 670 680 690 700 710 720 LSGDEQNHKL ILKSQGEPVA ANLQINGHFD RTLEQWKGTI SQVKFETPIG DVKSNQAIAV 730 740 750 760 770 780 SYDNKQTQAN IASHCWQNTD VELCFPQAFN AGKQGNIPFQ FKRVNLDLVN KLIEQNSLKG 790 800 810 820 830 840 NLQVQGNVAW FTDKPFQFTA NVDGNHLAFS QKLDYRTFKL YIPKLTLNAD IQNNNLVLKT 850 860 870 880 890 900 DINVHNQGRI VGDIHLNDLA KNRQLGGTLA IERLNLSIAN QLLTSGESVN GEVVSKLSFG 910 920 930 940 950 960 GNLEKPLLNG DFNIRNIRTK LKSMPVNITD GDIALRFNDN RSTLQGKIKT VDSHLNLTGR 970 980 990 1000 1010 1020 ANWANIEHWT TELNAQANNF NVDIPSMAKL RFSPNITIKA NPKELNLSGT VDIPWARIKI 1030 1040 1050 1060 1070 1080 DSLPDTAEPV SEDEVILNGP HKSKEELIKR EFAAKTKSGM EIRSDLRINI GKDVSLDAYG 1090 1100 1110 1120 1130 1140 LKTNLDGLLS VKQDKGNLGL FGQINLTKGR YASFGQDLLI RKGLISFSGQ ATQPTLNIEA 1150 1160 1170 1180 1190 1200 IRNPETMEDS KITAGVRVIG IADSPEVTIF SEPSKPQDQA LSYLLTGRSL ESSGEVGSTG 1210 1220 1230 1240 1250 1260 SVGAALIGLG ISKSGKLVGS IGEVFGIQDL NLGTSGVGDK SKVTVSGNIT NRLQIKYGVG 1270 1280 1290 LFDGLAEVTL RYRLMPQLYF QSVSSTNQVF DLLYKFEF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
[2]	"Two-dimensional map of the proteome of Haemophilus influenzae." Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C., Fountoulakis M. Electrophoresis 21:411-429(2000) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22356.1.
PIR	A64157.
RefSeq	NP_438856.1. NC_000907.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0696.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22356; AAC22356; HI_0696.
GeneID	950032.
KEGG	hin:HI0696.
PATRIC	20190013. VBIHaeInf48452_0728.
Phylogenomic databases
eggNOG	COG2911.
KO	K09800.
OMA	FPQAFNA.
ProtClustDB	CLSK870625.
Family and domain databases
InterPro	IPR007452. DUF490. [Graphical view]
Pfam	PF04357. DUF490. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAMB_HAEIN

Accession

Primary (citable) accession number: Q57523

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program