Q57519 (Y1296_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized endonuclease HI_1296
EC=3.1.-.-

Gene names

Ordered Locus Names:

HI_1296

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the thermonuclease family.

Ontologies

Keywords
Domain	Signal
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Chain	20 – 178	159	Uncharacterized endonuclease HI_1296		PRO_0000034397
Sites
	Active site	52	1	By similarity
	Active site	60	1	By similarity
	Active site	94	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q57519 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4169580DDFB6B340	FASTA	178	20,441
	10 20 30 40 50 60 MINRKILLTS LLLIFTVLSA CSREKNTCRV VKISDGDTLT CLTKGNKSIK VRLAEIDAPE 70 80 90 100 110 120 KSQAFGQKSK KTLSDLVYQK NVRLARKGKD RYQRTLAVVY YQKQNINLEM VKQGMAWAYK 130 140 150 160 170 QYSHDPIYLQ AQENAQAKGI GLWADNNPIE PSQWRRQEKI NMAFDYQTFP SSISLFPT

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22942.1.
PIR	A64115.
RefSeq	NP_439447.2. NC_000907.1.
3D structure databases
ProteinModelPortal	Q57519.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	950236.
GenomeReviews	Gene locus HI_1296 in contig L42023_GR.
KEGG	hin:HI1296.
NMPDR	fig|71421.1.peg.1235.
PATRIC	20191273. VBIHaeInf48452_1347.
TIGR	HI_1296.
Phylogenomic databases
HOGENOM	HBG752546.
OMA	IEPYKWR.
PhylomeDB	Q57519.
ProtClustDB	CLSK870283.
Enzyme and pathway databases
BioCyc	HINF71421:HI_1296-MONOMER.
Family and domain databases
InterPro	IPR016071. Staphylococal_nuclease_OB-fold. IPR006021. Staphylococcal_nuclease. IPR002071. Thermonucl_AS. [Graphical view]
Gene3D	G3DSA:2.40.50.90. SNase. 1 hit.
Pfam	PF00565. SNase. 1 hit. [Graphical view]
SMART	SM00318. SNc. 1 hit. [Graphical view]
SUPFAM	SSF50199. Staphylococal_nuclease_OB-fold. 1 hit.
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. Uncertain. PS01123. TNASE_1. 1 hit. PS01284. TNASE_2. 1 hit. PS50830. TNASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y1296_HAEIN

Accession

Primary (citable) accession number: Q57519
Secondary accession number(s): O05055

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program