Q57486 (Y608_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized transporter HI_0608

Gene names

Ordered Locus Names:

HI_0608

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. [View classification]

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	sodium ion transport Inferred from electronic annotation. Source: InterPro transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 461	461	Uncharacterized transporter HI_0608		PRO_0000172505
Regions
	Transmembrane	13 – 33	21	Helical; Potential
	Transmembrane	54 – 74	21	Helical; Potential
	Transmembrane	81 – 101	21	Helical; Potential
	Transmembrane	120 – 140	21	Helical; Potential
	Transmembrane	170 – 190	21	Helical; Potential
	Transmembrane	211 – 231	21	Helical; Potential
	Transmembrane	256 – 276	21	Helical; Potential
	Transmembrane	286 – 306	21	Helical; Potential
	Transmembrane	314 – 334	21	Helical; Potential
	Transmembrane	349 – 369	21	Helical; Potential
	Transmembrane	377 – 397	21	Helical; Potential
	Transmembrane	399 – 419	21	Helical; Potential
	Transmembrane	439 – 459	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q57486 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: B5E6F6965B38EF06	FASTA	461	49,762
	10 20 30 40 50 60 MGEMASLRSH KNGIIFILDI VLFFVLLNVL PFEPKANSGL ALLAFIAVLW LSEALHVTIT 70 80 90 100 110 120 ALLVPLLAVA LGLVSTKQAL VGFADPTIFL FFGGFSLATA LHIQKLDKLI ANKIMALARG 130 140 150 160 170 180 NLFIAVIYLF LITAFLSMWM SNTATAAMML PLAMGILSQL DREKDHNTYV FVLLGIAYSA 190 200 210 220 230 240 SIGGMGTLVG SPPNAIVASN LNLTFSDWLW YGLPIMIILL PLMIGILYII FKPKLHLNFE 250 260 270 280 290 300 QTFENIEMNP MRILTFIIFP VIALTWIFSG KINPFISGLL GLQKNIASFD SIVALLAAIV 310 320 330 340 350 360 ICSTGVASWK QIQSNTDWGV LMLFGGGLTL SAVLKDSGAS KILADSIVFM IDGQHFYLIG 370 380 390 400 410 420 LLVAAFIIFL TEFTSNTASA ALLVPIFISI AQSLGMPEIG LALIIGIGAS CAFMLPVATP 430 440 450 460 PNAIVFGSGQ VKQSEMVKVG FLLNLVCVVV IATMGYMFWL K

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22267.1.
PIR	I64080.
RefSeq	NP_438766.1. NC_000907.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0608.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22267; AAC22267; HI_0608.
GeneID	949996.
KEGG	hin:HI0608.
PATRIC	20189795. VBIHaeInf48452_0632.
Phylogenomic databases
eggNOG	COG0471.
KO	K14445.
OMA	RKTYVFV.
ProtClustDB	CLSK870380.
Family and domain databases
InterPro	IPR001898. Na/sul_symport. [Graphical view]
Pfam	PF00939. Na_sulph_symp. 1 hit. [Graphical view]
TIGRFAMs	TIGR00785. dass. 1 hit.
PROSITE	PS01271. NA_SULFATE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y608_HAEIN

Accession

Primary (citable) accession number: Q57486

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program