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Protein

Transcriptional repressor TraM

Gene

traM

Organism
Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Negatively regulates conjugation and the expression of tra genes by antagonizing TraR/AAI-dependent activation. TraM may either bind or modify TraR or AAI making them unavailable. Alternatively, TraM may bind tra promoters preventing TraR activation.

GO - Biological processi

Keywordsi

Molecular functionRepressor
Biological processConjugation, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor TraM
Gene namesi
Name:traM
Encoded oniPlasmid pTiA6NC0 Publication
OrganismiRhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Taxonomic identifieri358 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000656071 – 102Transcriptional repressor TraMAdd BLAST102

Structurei

Secondary structure

1102
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 5Combined sources3
Helixi16 – 21Combined sources6
Helixi26 – 52Combined sources27
Helixi56 – 59Combined sources4
Helixi67 – 93Combined sources27

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RFYX-ray1.60A/B1-102[»]
1UPGX-ray1.80A/B1-102[»]
1US6X-ray1.65A/B1-102[»]
ProteinModelPortaliQ57471.
SMRiQ57471.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57471.

Family & Domainsi

Family and domain databases

InterProiView protein in InterPro
IPR015309. Tscrpt_rep_TraM.
PfamiView protein in Pfam
PF09228. Prok-TraM. 1 hit.
PIRSFiPIRSF017930. Transcript_repress_TraM. 1 hit.
SUPFAMiSSF109631. SSF109631. 1 hit.

Sequencei

Sequence statusi: Complete.

Q57471-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELEDANVTK KVELRPLIGL TRGLPPTDLE TITIDAIRTH RRLVEKADEL
60 70 80 90 100
FQALPETYKT GQACGGPQHI RYIEASIEMH AQMSALNTLY SILGFIPKVV

VN
Length:102
Mass (Da):11,401
Last modified:November 1, 1997 - v1
Checksum:i78991A239468D7A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF242881 Genomic DNA. Translation: AAC28120.1.
U16786 Genomic DNA. Translation: AAA64838.1.
PIRiI39703.
RefSeqiNP_059700.1. NC_002377.1.
WP_010892388.1. NC_002377.1.

Genome annotation databases

GeneIDi1224219.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTRAM_RHIRD
AccessioniPrimary (citable) accession number: Q57471
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 10, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references