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Protein

Magnesium and cobalt efflux protein CorC

Gene

corC

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays a role in the transport of magnesium and cobalt ions.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Cobalt, Magnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Magnesium and cobalt efflux protein CorC
Gene namesi
Name:corC
Ordered Locus Names:HI_0301
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000883481 – 299Magnesium and cobalt efflux protein CorCAdd BLAST299

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0301.

Structurei

3D structure databases

ProteinModelPortaliQ57368.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 134CBS 1PROSITE-ProRule annotationAdd BLAST62
Domaini140 – 197CBS 2PROSITE-ProRule annotationAdd BLAST58

Sequence similaritiesi

Belongs to the UPF0053 family.Curated
Contains 2 CBS domains.PROSITE-ProRule annotation

Keywords - Domaini

CBS domain, Repeat

Phylogenomic databases

eggNOGiENOG4108JU5. Bacteria.
COG4535. LUCA.
KOiK06189.
OMAiFDETEDN.
PhylomeDBiQ57368.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57368-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDEQQNSNQ SENTKKPFFQ SLFGRFFQGE LKNREELVEV IRDSEQNDLI
60 70 80 90 100
DQNTREMIEG VMEIAELRVR DIMIPRSQII FIEDQQDLNT CLNTIIESAH
110 120 130 140 150
SRFPVIADAD DRDNIVGILH AKDLLKFLRE DAEVFDLSSL LRPVVIVPES
160 170 180 190 200
KRVDRMLKDF RSERFHMAIV VDEFGAVSGL VTIEDILEQI VGDIEDEFDE
210 220 230 240 250
EEIADIRQLS RHTYAVRALT DIDDFNAQFN TDFDDEEVDT IGGLIMQTFG
260 270 280 290
YLPKRGEEII LKNLQFKVTS ADSRRLIQLR VTVPDEHLAE MNNVDEKSE
Length:299
Mass (Da):34,584
Last modified:November 1, 1996 - v1
Checksum:i181F455BF44F0213
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC21966.1.
PIRiG64060.
RefSeqiNP_438468.1. NC_000907.1.
WP_005694364.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC21966; AAC21966; HI_0301.
GeneIDi949422.
KEGGihin:HI0301.
PATRICi20189143. VBIHaeInf48452_0318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC21966.1.
PIRiG64060.
RefSeqiNP_438468.1. NC_000907.1.
WP_005694364.1. NC_000907.1.

3D structure databases

ProteinModelPortaliQ57368.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0301.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC21966; AAC21966; HI_0301.
GeneIDi949422.
KEGGihin:HI0301.
PATRICi20189143. VBIHaeInf48452_0318.

Phylogenomic databases

eggNOGiENOG4108JU5. Bacteria.
COG4535. LUCA.
KOiK06189.
OMAiFDETEDN.
PhylomeDBiQ57368.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 2 hits.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCORC_HAEIN
AccessioniPrimary (citable) accession number: Q57368
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.