Q572P5 (Q572P5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tyrosine-protein kinase BTK isoform 65 EMBL CAI59842.1

Gene names

Name:

BTK EMBL CAI59842.1

Organism

Homo sapiens (Human) EMBL CAI59842.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	234 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Kinase EMBL CAI59842.1 Transferase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAI59842.1
	Non-terminal residue	234	1	EMBL CAI59842.1

Sequences

	Sequence		Length	Mass (Da)
	Q572P5 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: B0C99DAB3A359157	FASTA	234	27,048
	10 20 30 40 50 60 RHYVVCSTPQ SQYYLAEKHL FSTIPELINY HQHNSAGLIS RLKYPVSQQN KNAPSTAGLG 70 80 90 100 110 120 YGSWEIDPKD LTFLKELGTG QFGVVKYGKW RGQYDVAIKM IKEGSMSEDE FIEEAKVMMY 130 140 150 160 170 180 VLDDEYTSSV GSKFPVRWSP PEVLMYSKFS SKSDIWAFGV LMWEIYSLGK MPYERFTNSE 190 200 210 220 230 TAEHIAQGLR LYRPHLASEK VYTIMYSCWH EKADERPTFK ILLSNILDVM DEES

References

[1]

"Mimicry of a constitutively active pre-B cell receptor: Aberrant splicing links Bruton's tyrosine kinase to BCR-ABL1 in pre-B lymphoblastic leukemia." Feldhahn N., Klein F., Mooster J.L., Hadweh P., Sprangers M., Wartenberg M., Bekhite M.M., Hofmann W.K., Herzog S., Jumaa H., Rowley J.D., Muschen M. J. Exp. Med. 201:1837-1852(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: BCR-ABL1+ pre-B lymphoblastic leukemia EMBL CAI59842.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ888376 mRNA. Translation: CAI59842.1.
IPI	IPI00844337.
UniGene	Hs.159494.
3D structure databases
ProteinModelPortal	Q572P5.
SMR	Q572P5. Positions 1-56, 64-233.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc010nnl.2. human.
Phylogenomic databases
HOGENOM	HOG000233858.
Family and domain databases
Gene3D	3.30.505.10. 1 hit.
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR000980. SH2. [Graphical view]
Pfam	PF07714. Pkinase_Tyr. 2 hits. [Graphical view]
PRINTS	PR00109. TYRKINASE.
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS50001. SH2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	Q572P5.

Entry information

Entry name

Q572P5_HUMAN

Accession

Primary (citable) accession number: Q572P5
Secondary accession number(s): E9PEJ2

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	April 3, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.