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Q572P5 (Q572P5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:BTK EMBL CAI59842.1
OrganismHomo sapiens (Human) EMBL CAI59842.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length234 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains protein kinase domain. SAAS SAAS000980

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL CAI59842.1
Non-terminal residue2341 EMBL CAI59842.1

Sequences

Sequence LengthMass (Da)Tools
Q572P5 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: B0C99DAB3A359157

FASTA23427,048
        10         20         30         40         50         60 
RHYVVCSTPQ SQYYLAEKHL FSTIPELINY HQHNSAGLIS RLKYPVSQQN KNAPSTAGLG 

        70         80         90        100        110        120 
YGSWEIDPKD LTFLKELGTG QFGVVKYGKW RGQYDVAIKM IKEGSMSEDE FIEEAKVMMY 

       130        140        150        160        170        180 
VLDDEYTSSV GSKFPVRWSP PEVLMYSKFS SKSDIWAFGV LMWEIYSLGK MPYERFTNSE 

       190        200        210        220        230 
TAEHIAQGLR LYRPHLASEK VYTIMYSCWH EKADERPTFK ILLSNILDVM DEES 

« Hide

References

[1]"Mimicry of a constitutively active pre-B cell receptor: Aberrant splicing links Bruton's tyrosine kinase to BCR-ABL1 in pre-B lymphoblastic leukemia."
Feldhahn N., Klein F., Mooster J.L., Hadweh P., Sprangers M., Wartenberg M., Bekhite M.M., Hofmann W.K., Herzog S., Jumaa H., Rowley J.D., Muschen M.
J. Exp. Med. 201:1837-1852(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: BCR-ABL1+ pre-B lymphoblastic leukemia EMBL CAI59842.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ888376 mRNA. Translation: CAI59842.1.
UniGeneHs.159494.
Hs.733206.

3D structure databases

ProteinModelPortalQ572P5.
SMRQ572P5. Positions 1-56, 64-233.
ModBaseSearch...
MobiDBSearch...

Chemistry

BindingDBQ572P5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc010nnl.2. human.

Phylogenomic databases

HOGENOMHOG000233858.

Family and domain databases

Gene3D3.30.505.10. 1 hit.
InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR000980. SH2.
[Graphical view]
PfamPF07714. Pkinase_Tyr. 2 hits.
[Graphical view]
PRINTSPR00109. TYRKINASE.
SUPFAMSSF55550. SSF55550. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS50001. SH2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ572P5_HUMAN
AccessionPrimary (citable) accession number: Q572P5
Secondary accession number(s): E9PEJ2
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.