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Q57290

- Y740_HAEIN

UniProt

Q57290 - Y740_HAEIN

Protein

Probable phosphomannomutase

Gene

HI_0740

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

    Cofactori

    Binds 1 magnesium ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei86 – 861Phosphoserine intermediateBy similarity
    Metal bindingi86 – 861Magnesium; via phosphate groupBy similarity
    Metal bindingi236 – 2361MagnesiumBy similarity
    Metal bindingi238 – 2381MagnesiumBy similarity
    Metal bindingi240 – 2401MagnesiumBy similarity

    GO - Molecular functioni

    1. magnesium ion binding Source: InterPro
    2. phosphomannomutase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Isomerase

    Keywords - Ligandi

    Magnesium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable phosphomannomutase (EC:5.4.2.8)
    Short name:
    PMM
    Gene namesi
    Ordered Locus Names:HI_0740
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 485485Probable phosphomannomutasePRO_0000148021Add
    BLAST

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI0740.

    Structurei

    3D structure databases

    ProteinModelPortaliQ57290.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the phosphohexose mutase family.Curated

    Phylogenomic databases

    eggNOGiCOG1109.
    KOiK01840.
    OMAiAYLCENY.
    OrthoDBiEOG6103ZG.

    Family and domain databases

    Gene3Di3.30.310.50. 1 hit.
    3.40.120.10. 3 hits.
    InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
    IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
    IPR005845. A-D-PHexomutase_a/b/a-II.
    IPR005846. A-D-PHexomutase_a/b/a-III.
    IPR005843. A-D-PHexomutase_C.
    IPR016066. A-D-PHexomutase_CS.
    IPR005841. Alpha-D-phosphohexomutase_SF.
    [Graphical view]
    PfamiPF02878. PGM_PMM_I. 1 hit.
    PF02879. PGM_PMM_II. 1 hit.
    PF02880. PGM_PMM_III. 1 hit.
    PF00408. PGM_PMM_IV. 1 hit.
    [Graphical view]
    PRINTSiPR00509. PGMPMM.
    SUPFAMiSSF53738. SSF53738. 3 hits.
    SSF55957. SSF55957. 1 hit.
    PROSITEiPS00710. PGM_PMM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q57290-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGMNRVLVSQ AAGGLAEYLK GYDKEPSIVI GYDGRKNSDV FARDTAEIMA    50
    GAGVKAYLLP RKLPTPVLAY AIQYFDTTAG VMVTASHNPP EDNGYKVYLG 100
    KANGGGQIVS PADKDIAALI DKVAAGNIQD LPRSDNYVVL NDEVVDAYIT 150
    KTASLAKEPA CDINYVYTAM HGVGYEVLSK TLAKAGLPQP HVVADQVWPD 200
    GTFPTVNFPN PEEKGALDLA IKVAKEKNAE FIIANDPDAD RLAVAVPDAQ 250
    GNWKSLHGNV VGCFLGWYLA KQYQGKQGTL ACSLVSSPAL AEIAKKYSFQ 300
    SEETLTGFKY IGKVSGLLFG FEEALGYLVD PDKVRDKDGI SAAIVFLDLV 350
    RNLKKQGKTL ADYADEFTKE FGAYVSGQIS IRVSDLSEIG KLMTALRNNP 400
    PAEIAGVKVA QFIDHIKTDR QSDILVFNLE NGGRLIARPS GTEPKIKFYL 450
    DARGKDPKDA DRVLAEFDEG VRHILRQDAY GKQDC 485
    Length:485
    Mass (Da):52,568
    Last modified:November 1, 1996 - v1
    Checksum:iBBCF7D443623B34E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22400.1.
    PIRiI64157.
    RefSeqiNP_438900.2. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22400; AAC22400; HI_0740.
    GeneIDi949768.
    KEGGihin:HI0740.
    PATRICi20190123. VBIHaeInf48452_0777.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22400.1 .
    PIRi I64157.
    RefSeqi NP_438900.2. NC_000907.1.

    3D structure databases

    ProteinModelPortali Q57290.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0740.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22400 ; AAC22400 ; HI_0740 .
    GeneIDi 949768.
    KEGGi hin:HI0740.
    PATRICi 20190123. VBIHaeInf48452_0777.

    Phylogenomic databases

    eggNOGi COG1109.
    KOi K01840.
    OMAi AYLCENY.
    OrthoDBi EOG6103ZG.

    Family and domain databases

    Gene3Di 3.30.310.50. 1 hit.
    3.40.120.10. 3 hits.
    InterProi IPR005844. A-D-PHexomutase_a/b/a-I.
    IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
    IPR005845. A-D-PHexomutase_a/b/a-II.
    IPR005846. A-D-PHexomutase_a/b/a-III.
    IPR005843. A-D-PHexomutase_C.
    IPR016066. A-D-PHexomutase_CS.
    IPR005841. Alpha-D-phosphohexomutase_SF.
    [Graphical view ]
    Pfami PF02878. PGM_PMM_I. 1 hit.
    PF02879. PGM_PMM_II. 1 hit.
    PF02880. PGM_PMM_III. 1 hit.
    PF00408. PGM_PMM_IV. 1 hit.
    [Graphical view ]
    PRINTSi PR00509. PGMPMM.
    SUPFAMi SSF53738. SSF53738. 3 hits.
    SSF55957. SSF55957. 1 hit.
    PROSITEi PS00710. PGM_PMM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
    2. "Two-dimensional map of the proteome of Haemophilus influenzae."
      Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C., Fountoulakis M.
      Electrophoresis 21:411-429(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiY740_HAEIN
    AccessioniPrimary (citable) accession number: Q57290
    Secondary accession number(s): O05032
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3