Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable phosphomannomutase

Gene

HI_0740

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei86 – 861Phosphoserine intermediateBy similarity
Metal bindingi86 – 861Magnesium; via phosphate groupBy similarity
Metal bindingi236 – 2361MagnesiumBy similarity
Metal bindingi238 – 2381MagnesiumBy similarity
Metal bindingi240 – 2401MagnesiumBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable phosphomannomutase (EC:5.4.2.8)
Short name:
PMM
Gene namesi
Ordered Locus Names:HI_0740
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485Probable phosphomannomutasePRO_0000148021Add
BLAST

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0740.

Structurei

3D structure databases

ProteinModelPortaliQ57290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Phylogenomic databases

eggNOGiENOG4107QSU. Bacteria.
COG1109. LUCA.
KOiK01840.
OMAiQAGSMGM.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSiPR00509. PGMPMM.
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57290-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGMNRVLVSQ AAGGLAEYLK GYDKEPSIVI GYDGRKNSDV FARDTAEIMA
60 70 80 90 100
GAGVKAYLLP RKLPTPVLAY AIQYFDTTAG VMVTASHNPP EDNGYKVYLG
110 120 130 140 150
KANGGGQIVS PADKDIAALI DKVAAGNIQD LPRSDNYVVL NDEVVDAYIT
160 170 180 190 200
KTASLAKEPA CDINYVYTAM HGVGYEVLSK TLAKAGLPQP HVVADQVWPD
210 220 230 240 250
GTFPTVNFPN PEEKGALDLA IKVAKEKNAE FIIANDPDAD RLAVAVPDAQ
260 270 280 290 300
GNWKSLHGNV VGCFLGWYLA KQYQGKQGTL ACSLVSSPAL AEIAKKYSFQ
310 320 330 340 350
SEETLTGFKY IGKVSGLLFG FEEALGYLVD PDKVRDKDGI SAAIVFLDLV
360 370 380 390 400
RNLKKQGKTL ADYADEFTKE FGAYVSGQIS IRVSDLSEIG KLMTALRNNP
410 420 430 440 450
PAEIAGVKVA QFIDHIKTDR QSDILVFNLE NGGRLIARPS GTEPKIKFYL
460 470 480
DARGKDPKDA DRVLAEFDEG VRHILRQDAY GKQDC
Length:485
Mass (Da):52,568
Last modified:November 1, 1996 - v1
Checksum:iBBCF7D443623B34E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22400.1.
PIRiI64157.
RefSeqiNP_438900.2. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22400; AAC22400; HI_0740.
GeneIDi949768.
KEGGihin:HI0740.
PATRICi20190123. VBIHaeInf48452_0777.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22400.1.
PIRiI64157.
RefSeqiNP_438900.2. NC_000907.1.

3D structure databases

ProteinModelPortaliQ57290.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0740.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22400; AAC22400; HI_0740.
GeneIDi949768.
KEGGihin:HI0740.
PATRICi20190123. VBIHaeInf48452_0777.

Phylogenomic databases

eggNOGiENOG4107QSU. Bacteria.
COG1109. LUCA.
KOiK01840.
OMAiQAGSMGM.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSiPR00509. PGMPMM.
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY740_HAEIN
AccessioniPrimary (citable) accession number: Q57290
Secondary accession number(s): O05032
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.