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Q57290 (Y740_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable phosphomannomutase

Short name=PMM
EC=5.4.2.8
Gene names
Ordered Locus Names:HI_0740
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length485 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Sequence similarities

Belongs to the phosphohexose mutase family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: InterPro

phosphomannomutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 485485Probable phosphomannomutase
PRO_0000148021

Sites

Active site861Phosphoserine intermediate By similarity
Metal binding861Magnesium; via phosphate group By similarity
Metal binding2361Magnesium By similarity
Metal binding2381Magnesium By similarity
Metal binding2401Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q57290 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: BBCF7D443623B34E

FASTA48552,568
        10         20         30         40         50         60 
MGMNRVLVSQ AAGGLAEYLK GYDKEPSIVI GYDGRKNSDV FARDTAEIMA GAGVKAYLLP 

        70         80         90        100        110        120 
RKLPTPVLAY AIQYFDTTAG VMVTASHNPP EDNGYKVYLG KANGGGQIVS PADKDIAALI 

       130        140        150        160        170        180 
DKVAAGNIQD LPRSDNYVVL NDEVVDAYIT KTASLAKEPA CDINYVYTAM HGVGYEVLSK 

       190        200        210        220        230        240 
TLAKAGLPQP HVVADQVWPD GTFPTVNFPN PEEKGALDLA IKVAKEKNAE FIIANDPDAD 

       250        260        270        280        290        300 
RLAVAVPDAQ GNWKSLHGNV VGCFLGWYLA KQYQGKQGTL ACSLVSSPAL AEIAKKYSFQ 

       310        320        330        340        350        360 
SEETLTGFKY IGKVSGLLFG FEEALGYLVD PDKVRDKDGI SAAIVFLDLV RNLKKQGKTL 

       370        380        390        400        410        420 
ADYADEFTKE FGAYVSGQIS IRVSDLSEIG KLMTALRNNP PAEIAGVKVA QFIDHIKTDR 

       430        440        450        460        470        480 
QSDILVFNLE NGGRLIARPS GTEPKIKFYL DARGKDPKDA DRVLAEFDEG VRHILRQDAY 


GKQDC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22400.1.
PIRI64157.
RefSeqNP_438900.2. NC_000907.1.

3D structure databases

ProteinModelPortalQ57290.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0740.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22400; AAC22400; HI_0740.
GeneID949768.
KEGGhin:HI0740.
PATRIC20190123. VBIHaeInf48452_0777.

Phylogenomic databases

eggNOGCOG1109.
KOK01840.
OMANYVYTAM.
OrthoDBEOG6103ZG.
ProtClustDBCLSK870357.

Family and domain databases

Gene3D3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSPR00509. PGMPMM.
SUPFAMSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY740_HAEIN
AccessionPrimary (citable) accession number: Q57290
Secondary accession number(s): O05032
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names