ID   Q57221_YERPU            Unreviewed;       151 AA.
AC   Q57221;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   24-JAN-2024, entry version 97.
DE   SubName: Full=-derived mitogen {ECO:0000313|EMBL:BAA07619.1};
DE   SubName: Full=YPM {ECO:0000313|EMBL:AAK28542.1, ECO:0000313|EMBL:BAA07528.1};
DE   Flags: Precursor;
GN   Name=ypm {ECO:0000313|EMBL:BAA07619.1};
OS   Yersinia pseudotuberculosis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=633 {ECO:0000313|EMBL:BAA07619.1};
RN   [1] {ECO:0000313|EMBL:BAA07619.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CYP86-15 {ECO:0000313|EMBL:BAA07619.1};
RX   PubMed=7730627;
RA   Miyoshi-Akiyama T., Abe A., Kato H., Kawahara K., Narimatsu H.,
RA   Uchiyama T.;
RT   "DNA sequencing of the gene encoding a bacterial superantigen, Yersinia
RT   pseudotuberculosis-derived mitogen (YPM), and characterization of the gene
RT   product, cloned YPM.";
RL   J. Immunol. 154:5228-5234(1995).
RN   [2] {ECO:0000313|EMBL:BAA07528.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=KUR-1 {ECO:0000313|EMBL:BAA07528.1};
RX   PubMed=7751634;
RA   Ito Y., Abe J., Yoshino K., Takeda T., Kohsaka T.;
RT   "Sequence analysis of the gene for a novel superantigen produced by
RT   Yersinia pseudotuberculosis and expression of the recombinant protein.";
RL   J. Immunol. 154:5896-5906(1995).
RN   [3] {ECO:0000313|EMBL:AAK28542.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=AH {ECO:0000313|EMBL:AAK28542.1};
RA   Frohberg C.;
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AAK28542.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=AH {ECO:0000313|EMBL:AAK28542.1};
RX   PubMed=12142419; DOI=10.1128/JB.184.16.4489-4499.2002;
RA   Carnoy C., Floquet S., Marceau M., Sebbane F., Haentjens-Herwegh S.,
RA   Devalckenaere A., Simonet M.;
RT   "The superantigen gene ypm is located in an unstable chromosomal locus of
RT   Yersinia pseudotuberculosis.";
RL   J. Bacteriol. 184:4489-4499(2002).
RN   [5] {ECO:0007829|PDB:1PM4, ECO:0007829|PDB:1POQ}
RP   X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 33-151, AND DISULFIDE BONDS.
RX   PubMed=14725774; DOI=10.1016/j.str.2003.12.002;
RA   Donadini R., Liew C.W., Kwan A.H., Mackay J.P., Fields B.A.;
RT   "Crystal and solution structures of a superantigen from Yersinia
RT   pseudotuberculosis reveal a jelly-roll fold.";
RL   Structure 12:145-156(2004).
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DR   EMBL; AF335466; AAK28542.1; -; Genomic_DNA.
DR   EMBL; D38523; BAA07528.1; -; Genomic_DNA.
DR   EMBL; D38638; BAA07619.1; -; Genomic_DNA.
DR   RefSeq; WP_012105075.1; NZ_SDWX01000008.1.
DR   PDB; 1PM4; X-ray; 1.75 A; A/B/C=33-151.
DR   PDB; 1POQ; NMR; -; A=34-151.
DR   PDBsum; 1PM4; -.
DR   PDBsum; 1POQ; -.
DR   AlphaFoldDB; Q57221; -.
DR   SMR; Q57221; -.
DR   EvolutionaryTrace; Q57221; -.
DR   Gene3D; 2.60.120.510; Mitogen Ypm; 1.
DR   InterPro; IPR015227; Mitogen_YERPS.
DR   InterPro; IPR036475; Mitogen_Ypm_sf.
DR   Pfam; PF09144; YpM; 1.
DR   SUPFAM; SSF101606; Superantigen (mitogen) Ypm; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:1PM4, ECO:0007829|PDB:1POQ};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..151
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007704299"
FT   DISULFID        52..149
FT                   /evidence="ECO:0007829|PDB:1PM4, ECO:0007829|PDB:1POQ"
SQ   SEQUENCE   151 AA;  16679 MW;  481B32212F3CC65E CRC64;
     MKNKLLSLLT FTLFSGVALA TDYDNTLNSI PSLRIPNIAT YTGTIQGKGE VCIIGNKEGK
     TRGGELYAVL HSTNVNADMT LILLRNVGGN GWGEIKRNDI DKPLKYEDYY TSGLSWIWKI
     KNNSSETSNY SLDATVHDDK EDSDVLTKCP V
//