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Protein
Submitted name:

-derived mitogen

Gene

ypm

Organism
Yersinia pseudotuberculosis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
-derived mitogenImported
Submitted name:
Superantigen YPMaImported
Submitted name:
YPMImported
Gene namesi
Name:ypmImported
OrganismiYersinia pseudotuberculosisImported
Taxonomic identifieri633 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 PotentialImportedAdd
BLAST
Chaini21 – 151131Yersinia pseudotuberculosis-derived mitogen (YPM)ImportedPRO_5000139868Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi52 ↔ 149Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PM4X-ray1.76A/B/C33-151[»]
1POQNMR-A34-151[»]
ProteinModelPortaliQ57221.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57221.

Family & Domainsi

Keywords - Domaini

SignalImported

Family and domain databases

Gene3Di2.60.120.510. 1 hit.
InterProiIPR015227. Mitogen_YERPS.
[Graphical view]
PfamiPF09144. YpM. 1 hit.
[Graphical view]
SUPFAMiSSF101606. SSF101606. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q57221-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNKLLSLLT FTLFSGVALA TDYDNTLNSI PSLRIPNIAT YTGTIQGKGE
60 70 80 90 100
VCIIGNKEGK TRGGELYAVL HSTNVNADMT LILLRNVGGN GWGEIKRNDI
110 120 130 140 150
DKPLKYEDYY TSGLSWIWKI KNNSSETSNY SLDATVHDDK EDSDVLTKCP

V
Length:151
Mass (Da):16,679
Last modified:November 1, 1996 - v1
Checksum:i481B32212F3CC65E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335466 Genomic DNA. Translation: AAK28542.1.
D38523 Genomic DNA. Translation: BAA07528.1.
D38638 Genomic DNA. Translation: BAA07619.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335466 Genomic DNA. Translation: AAK28542.1.
D38523 Genomic DNA. Translation: BAA07528.1.
D38638 Genomic DNA. Translation: BAA07619.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PM4X-ray1.76A/B/C33-151[»]
1POQNMR-A34-151[»]
ProteinModelPortaliQ57221.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ57221.

Family and domain databases

Gene3Di2.60.120.510. 1 hit.
InterProiIPR015227. Mitogen_YERPS.
[Graphical view]
PfamiPF09144. YpM. 1 hit.
[Graphical view]
SUPFAMiSSF101606. SSF101606. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "DNA sequencing of the gene encoding a bacterial superantigen, Yersinia pseudotuberculosis-derived mitogen (YPM), and characterization of the gene product, cloned YPM."
    Miyoshi-Akiyama T., Abe A., Kato H., Kawahara K., Narimatsu H., Uchiyama T.
    J. Immunol. 154:5228-5234(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CYP86-15Imported.
  2. "Sequence analysis of the gene for a novel superantigen produced by Yersinia pseudotuberculosis and expression of the recombinant protein."
    Ito Y., Abe J., Yoshino K., Takeda T., Kohsaka T.
    J. Immunol. 154:5896-5906(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: KUR-1Imported.
  3. Carnoy C.A., Floquet S., Herwegh S., Devalckenaere A., Simonet M.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AHImported.
  4. "The superantigen gene ypm is located in an unstable chromosomal locus of Yersinia pseudotuberculosis."
    Carnoy C., Floquet S., Marceau M., Sebbane F., Haentjens-Herwegh S., Devalckenaere A., Simonet M.
    J. Bacteriol. 184:4489-4499(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AHImported.
  5. "Crystal and solution structures of a superantigen from Yersinia pseudotuberculosis reveal a jelly-roll fold."
    Donadini R., Liew C.W., Kwan A.H., Mackay J.P., Fields B.A.
    Structure 12:145-156(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.76 ANGSTROMS) OF 33-151, ACTIVE SITE.

Entry informationi

Entry nameiQ57221_YERPU
AccessioniPrimary (citable) accession number: Q57221
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 4, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.