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Q57039 (6PGL_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphogluconolactonase
Short name=6PGL
EC=3.1.1.31
Gene names
Name:pgl
Synonyms:devB
Ordered Locus Names:HI_0556
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.

Sequence similarities

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Sequence caution

The sequence AAC22212.1 differs from that shown. Reason: Frameshift at position 29.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2322326-phosphogluconolactonase
PRO_0000090094

Sequences

Sequence LengthMass (Da)Tools
Q57039 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: 4744738C62D3B11D

FASTA23226,307
        10         20         30         40         50         60 
MNYISFPTAQ HAVDKIAQEF VIYSQLNHPV HISLSGGSTP KLLFKTLAKS PYAEQINWKN 

        70         80         90        100        110        120 
LHFWWGDDRM VPPSDPESNY GEVQKLLFDH IQIPAENIHR IRGENEPHFE LKRFEEELSA 

       130        140        150        160        170        180 
VIPNGVFDWI ILGMGIDGHT ASLFPHQTNF DDENLAVIAK HPESGQIRIS KTAKLIEQAK 

       190        200        210        220        230 
RITYLVTGES KADILKEIQT TPAENLPYPA AKIKAKNGVT EWYLDKAAVR LL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC22212.1. Frameshift.
PIRD64077.
RefSeqNP_438714.1. NC_000907.1.

3D structure databases

ProteinModelPortalQ57039.
SMRQ57039. Positions 1-228.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID949954.
GenomeReviewsGene locus HI_0556 in contig L42023_GR.
KEGGhin:HI0556.
PATRIC20189667. VBIHaeInf48452_0576.
TIGRHI_0556.

Phylogenomic databases

HOGENOMHBG725991.
OMAAEQINWK.
PhylomeDBQ57039.

Enzyme and pathway databases

BioCycHINF71421:HI_0556-MONOMER.

Family and domain databases

InterProIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
KOK01057.
PfamPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsTIGR01198. Pgl. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL_HAEIN
AccessionPrimary (citable) accession number: Q57039
Secondary accession number(s): P96334
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: January 25, 2012
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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