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Protein

UPF0053 protein HI_0107

Gene

HI_0107

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0053 protein HI_0107
Gene namesi
Ordered Locus Names:HI_0107
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence AnalysisAdd
BLAST
Transmembranei65 – 8521HelicalSequence AnalysisAdd
BLAST
Transmembranei92 – 11221HelicalSequence AnalysisAdd
BLAST
Transmembranei126 – 14621HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 420420UPF0053 protein HI_0107PRO_0000088358Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0107.

Structurei

Secondary structure

1
420
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi350 – 3534Combined sources
Helixi358 – 3658Combined sources
Helixi377 – 3848Combined sources
Beta strandi394 – 3974Combined sources
Beta strandi400 – 4089Combined sources
Beta strandi411 – 4199Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LAEX-ray1.45A343-420[»]
ProteinModelPortaliQ57017.
SMRiQ57017. Positions 343-420.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ57017.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 184176DUF21Add
BLAST
Domaini208 – 26861CBS 1PROSITE-ProRule annotationAdd
BLAST
Domaini273 – 33361CBS 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the UPF0053 family.Curated
Contains 2 CBS domains.PROSITE-ProRule annotation
Contains 1 DUF21 domain.Curated

Keywords - Domaini

CBS domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG4536.
OMAiNFQHNKE.
OrthoDBiEOG60W7V4.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR002550. DUF21.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
PF01595. DUF21. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 1 hit.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q57017-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSIPLSTLF IILIICLVLS AYFSGSETGL LSLNKYRLRF LSEQGNKGAK
60 70 80 90 100
KAEKLLEKPD TLLSFILIFN NLVNISASAI ATVIGMRLYG DAGVAIATGL
110 120 130 140 150
LTFVMLVFSE IFPKTVAAMH AEKVSFFSSH ILTSLLKIFY PLVWLMNIFT
160 170 180 190 200
KSLMQIVGLK LDMQKQVISS EELRSIVSEA GEATPNEQHP QMLLSILDME
210 220 230 240 250
TVTVDDIMVP RNEIGGINID DDWRAIMRQL NHAAHNRVVL YKGSLDEQVL
260 270 280 290 300
GILRVREAFR LLLEKNEFTK ETLIRAADEV YFIPESTPLK TQLANFRTNK
310 320 330 340 350
ERIGLVVDEY GDIKGLVTLE DILEEIVGDF TTSTAPSIDK EVIQQSDGSM
360 370 380 390 400
IIDGSANLRD LNKMFNWELD TEDARTFNGL ILEHLEEIPD EGTICEIDGL
410 420
LITILEVGDN MIKQAKVVKL
Length:420
Mass (Da):46,960
Last modified:December 15, 1998 - v2
Checksum:i7CFFD76A12937231
GO

Sequence cautioni

The sequence AAC21785.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC21785.1. Different initiation.
PIRiH64142.
RefSeqiNP_438281.1. NC_000907.1.
WP_010868936.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC21785; AAC21785; HI_0107.
GeneIDi951005.
KEGGihin:HI0107.
PATRICi20188683. VBIHaeInf48452_0111.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC21785.1. Different initiation.
PIRiH64142.
RefSeqiNP_438281.1. NC_000907.1.
WP_010868936.1. NC_000907.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LAEX-ray1.45A343-420[»]
ProteinModelPortaliQ57017.
SMRiQ57017. Positions 343-420.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0107.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC21785; AAC21785; HI_0107.
GeneIDi951005.
KEGGihin:HI0107.
PATRICi20188683. VBIHaeInf48452_0111.

Phylogenomic databases

eggNOGiCOG4536.
OMAiNFQHNKE.
OrthoDBiEOG60W7V4.

Miscellaneous databases

EvolutionaryTraceiQ57017.

Family and domain databases

Gene3Di3.30.465.10. 1 hit.
InterProiIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR002550. DUF21.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamiPF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
PF01595. DUF21. 1 hit.
[Graphical view]
SMARTiSM00116. CBS. 1 hit.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMiSSF56176. SSF56176. 1 hit.
PROSITEiPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiY107_HAEIN
AccessioniPrimary (citable) accession number: Q57017
Secondary accession number(s): P96330
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 15, 1998
Last modified: July 22, 2015
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.