UPF0053 protein HI_0107 - Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Preferred order of sections

Names and origin

Protein names

Recommended name:
UPF0053 protein HI_0107

Gene names

Ordered Locus Names:

HI_0107

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length	420 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the UPF0053 family.

Contains 2 CBS domains.

Contains 1 DUF21 domain.

Sequence caution

The sequence AAC21785.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	CBS domain Repeat Transmembrane Transmembrane helix
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 420

420

UPF0053 protein HI_0107

PRO_0000088358

Regions

Transmembrane

3 – 23

21

Helical; Potential

Transmembrane

65 – 85

21

Helical; Potential

Transmembrane

92 – 112

21

Helical; Potential

Transmembrane

126 – 146

21

Helical; Potential

Domain

9 – 184

176

DUF21

Domain

208 – 268

61

CBS 1

Domain

273 – 333

61

CBS 2

Secondary structure

1

.

420

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

Q57017 [UniParc].

Last modified December 15, 1998. Version 2.
Checksum: 7CFFD76A12937231
Show »

FASTA

420

46,960

        10         20         30         40         50         60 
MDSIPLSTLF IILIICLVLS AYFSGSETGL LSLNKYRLRF LSEQGNKGAK KAEKLLEKPD 

        70         80         90        100        110        120 
TLLSFILIFN NLVNISASAI ATVIGMRLYG DAGVAIATGL LTFVMLVFSE IFPKTVAAMH 

       130        140        150        160        170        180 
AEKVSFFSSH ILTSLLKIFY PLVWLMNIFT KSLMQIVGLK LDMQKQVISS EELRSIVSEA 

       190        200        210        220        230        240 
GEATPNEQHP QMLLSILDME TVTVDDIMVP RNEIGGINID DDWRAIMRQL NHAAHNRVVL 

       250        260        270        280        290        300 
YKGSLDEQVL GILRVREAFR LLLEKNEFTK ETLIRAADEV YFIPESTPLK TQLANFRTNK 

       310        320        330        340        350        360 
ERIGLVVDEY GDIKGLVTLE DILEEIVGDF TTSTAPSIDK EVIQQSDGSM IIDGSANLRD 

       370        380        390        400        410        420 
LNKMFNWELD TEDARTFNGL ILEHLEEIPD EGTICEIDGL LITILEVGDN MIKQAKVVKL

« Hide

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd."
Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I.

Venter J.C.
Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

L42023 Genomic DNA. Translation: AAC21785.1. Different initiation.

PIR

H64142.

RefSeq

NP_438281.1. NC_000907.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3LAE	X-ray	1.45	A	343-420	[»]

ProteinModelPortal

Q57017.

SMR

Q57017. Positions 343-420.

ModBase

Search...

Protein-protein interaction databases

STRING

71421.HI0107.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAC21785; AAC21785; HI_0107.

GeneID

951005.

KEGG

hin:HI0107.

PATRIC

20188683. VBIHaeInf48452_0111.

Phylogenomic databases

eggNOG

COG4536.

OMA

VENTESW.

ProtClustDB

CLSK2458832.

Family and domain databases

Gene3D

3.30.465.10. 1 hit.

InterPro

IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR000644. Cysta_beta_synth_core.
IPR002550. DUF21.
IPR005170. Transptr-assoc_dom.
[Graphical view]

Pfam

PF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
PF01595. DUF21. 1 hit.
[Graphical view]

SMART

SM00116. CBS. 1 hit.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]

PROSITE

PS51371. CBS. 2 hits.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q57017.

Entry information

Entry name

Y107_HAEIN

Accession

Primary (citable) accession number: Q57017
Secondary accession number(s): P96330

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	December 15, 1998
Last modified:	May 1, 2013
This is version 90 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families