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Q56ZI2 (PATL2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Patellin-2
Gene names
Name:PATL2
Ordered Locus Names:At1g22530
ORF Names:F12K8.13
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length683 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Carrier protein that may be involved in membrane-trafficking events associated with cell plate formation during cytokinesis. Binds to some hydrophobic molecules such as phosphoinositides and promotes their transfer between the different cellular sites By similarity.

Subunit structure

Interacts with the deubiquitinating enzyme AMSH3. Ref.8

Subcellular location

Membrane; Peripheral membrane protein By similarity. Cytoplasm By similarity. Note: Mainly membrane-associated. Also cytoplasmic By similarity.

Miscellaneous

'Patella' means 'small plate' in Latin.

Sequence similarities

Belongs to the patellin family.

Contains 1 CRAL-TRIO domain.

Contains 1 GOLD domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.9
Chain2 – 683682Patellin-2
PRO_0000215586

Regions

Domain404 – 576173CRAL-TRIO
Domain580 – 681102GOLD
Coiled coil86 – 16378 Potential
Compositional bias18 – 350333Glu-rich

Amino acid modifications

Modified residue21N-acetylalanine Ref.9
Modified residue791Phosphoserine Ref.7

Sequences

Sequence LengthMass (Da)Tools
Q56ZI2 [UniParc].

Last modified October 25, 2005. Version 2.
Checksum: E0626F746EDC15AB

FASTA68376,008
        10         20         30         40         50         60 
MAQEEIQKPT ASVPVVKEET PAPVKEVEVP VTTEKAVAAP APEATEEKVV SEVAVPETEV 

        70         80         90        100        110        120 
TAVKEEEVAT GKEILQSESF KEEGYLASEL QEAEKNALAE LKELVREALN KREFTAPPPP 

       130        140        150        160        170        180 
PAPVKEEKVE EKKTEETEEK KEEVKTEEKS LEAETKEEEK SAAPATVETK KEEILAAPAP 

       190        200        210        220        230        240 
IVAETKKEET PVAPAPVETK PAAPVVAETK KEEILPAAPV TTETKVEEKV VPVETTPAAP 

       250        260        270        280        290        300 
VTTETKEEEK AAPVTTETKE EEKAAPGETK KEEKATASTQ VKRASKFIKD IFVSVTTSEK 

       310        320        330        340        350        360 
KKEEEKPAVV TIEKAFAADQ EEETKTVEAV EESIVSITLP ETAAYVEPEE VSIWGIPLLE 

       370        380        390        400        410        420 
DERSDVILLK FLRARDFKVK EAFTMLKNTV QWRKENKIDD LVSEDLEGSE FEKLVFTHGV 

       430        440        450        460        470        480 
DKQGHVVIYS SYGEFQNKEI FSDKEKLSKF LKWRIQFQEK CVRSLDFSPE AKSSFVFVSD 

       490        500        510        520        530        540 
FRNAPGLGQR ALWQFIKRAV KQFEDNYPEF VAKELFINVP WWYIPYYKTF GSIITSPRTR 

       550        560        570        580        590        600 
SKMVLSGPSK SAETIFKYVA PEVVPVKYGG LSKDSPFTVE DGVTEAVVKS TSKYTIDLPA 

       610        620        630        640        650        660 
TEGSTLSWEL RVLGADVSYG AQFEPSNEAS YTVIVSKNRK VGLTDEPVIT DSFKASEAGK 

       670        680 
VVITIDNQTF KKKKVLYRSK TQA 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 620-683.
Strain: cv. Columbia.
[5]"Patellin1, a novel Sec14-like protein, localizes to the cell plate and binds phosphoinositides."
Peterman T.K., Ohol Y.M., McReynolds L.J., Luna E.J.
Plant Physiol. 136:3080-3094(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[6]"Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis."
Niittylae T., Fuglsang A.T., Palmgren M.G., Frommer W.B., Schulze W.X.
Mol. Cell. Proteomics 6:1711-1726(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Seedling.
[7]"Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks."
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A., Grossmann J., Gruissem W., Baginsky S.
Plant Physiol. 150:889-903(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-79, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana."
Isono E., Katsiarimpa A., Mueller I.K., Anzenberger F., Stierhof Y.-D., Geldner N., Chory J., Schwechheimer C.
Plant Cell 22:1826-1837(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH AMSH3.
[9]"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC006551 Genomic DNA. Translation: AAF18525.1.
CP002684 Genomic DNA. Translation: AEE30253.1.
AY091145 mRNA. Translation: AAM14094.1.
AY133810 mRNA. Translation: AAM91744.1.
AK220983 mRNA. Translation: BAD94580.1.
PIRE86358.
RefSeqNP_173669.1. NM_102102.2.
UniGeneAt.25355.

3D structure databases

ProteinModelPortalQ56ZI2.
SMRQ56ZI2. Positions 365-620.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid24098. 1 interaction.
STRING3702.AT1G22530.1-P.

Proteomic databases

PaxDbQ56ZI2.
PRIDEQ56ZI2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G22530.1; AT1G22530.1; AT1G22530.
GeneID838859.
KEGGath:AT1G22530.

Organism-specific databases

TAIRAT1G22530.

Phylogenomic databases

eggNOGNOG270325.
HOGENOMHOG000238518.
InParanoidQ56ZI2.
OMASAETIFK.
PhylomeDBQ56ZI2.
ProtClustDBCLSN2679530.

Gene expression databases

ArrayExpressQ56ZI2.
GenevestigatorQ56ZI2.

Family and domain databases

Gene3D3.40.525.10. 2 hits.
InterProIPR001071. CRAL-bd_toc_tran.
IPR001251. CRAL-TRIO_dom.
IPR011074. CRAL/TRIO_N_dom.
IPR009038. GOLD.
[Graphical view]
PfamPF00650. CRAL_TRIO. 1 hit.
PF03765. CRAL_TRIO_N. 1 hit.
[Graphical view]
PRINTSPR00180. CRETINALDHBP.
SMARTSM01100. CRAL_TRIO_N. 1 hit.
SM00516. SEC14. 1 hit.
[Graphical view]
SUPFAMSSF101576. SSF101576. 1 hit.
SSF46938. SSF46938. 1 hit.
SSF52087. SSF52087. 1 hit.
PROSITEPS50191. CRAL_TRIO. 1 hit.
PS50866. GOLD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePATL2_ARATH
AccessionPrimary (citable) accession number: Q56ZI2
Secondary accession number(s): Q9SK94
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: April 16, 2014
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names