SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q56YT0

- LAC3_ARATH

UniProt

Q56YT0 - LAC3_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Laccase-3
Gene
LAC3, At2g30210, T9D9.2
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi83 – 831Copper 1; type 2 By similarity
Metal bindingi85 – 851Copper 2; type 3 By similarity
Metal bindingi128 – 1281Copper 2; type 3 By similarity
Metal bindingi130 – 1301Copper 3; type 3 By similarity
Metal bindingi471 – 4711Copper 4; type 1 By similarity
Metal bindingi474 – 4741Copper 1; type 2 By similarity
Metal bindingi476 – 4761Copper 3; type 3 By similarity
Metal bindingi533 – 5331Copper 3; type 3 By similarity
Metal bindingi534 – 5341Copper 4; type 1 By similarity
Metal bindingi535 – 5351Copper 2; type 3 By similarity
Metal bindingi539 – 5391Copper 4; type 1 By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT2G30210-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-3 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 3
Diphenol oxidase 3
Urishiol oxidase 3
Gene namesi
Name:LAC3
Ordered Locus Names:At2g30210
ORF Names:T9D9.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G30210.

Subcellular locationi

Secretedextracellular spaceapoplast Reviewed prediction

GO - Cellular componenti

  1. apoplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525 Reviewed prediction
Add
BLAST
Chaini26 – 570545Laccase-3
PRO_0000283631Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi79 – 791N-linked (GlcNAc...) Reviewed prediction
Glycosylationi188 – 1881N-linked (GlcNAc...) Reviewed prediction
Glycosylationi298 – 2981N-linked (GlcNAc...) Reviewed prediction
Glycosylationi332 – 3321N-linked (GlcNAc...) Reviewed prediction
Glycosylationi383 – 3831N-linked (GlcNAc...) Reviewed prediction
Glycosylationi393 – 3931N-linked (GlcNAc...) Reviewed prediction
Glycosylationi433 – 4331N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ56YT0.
PRIDEiQ56YT0.

Expressioni

Tissue specificityi

Mostly expressed in roots and siliques.2 Publications

Gene expression databases

GenevestigatoriQ56YT0.

Structurei

3D structure databases

ProteinModelPortaliQ56YT0.
SMRiQ56YT0. Positions 43-549.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 149117Plastocyanin-like 1
Add
BLAST
Domaini159 – 310152Plastocyanin-like 2
Add
BLAST
Domaini419 – 554136Plastocyanin-like 3
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ56YT0.
OMAiRYNISIH.
PhylomeDBiQ56YT0.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q56YT0-1 [UniParc]FASTAAdd to Basket

« Hide

MESFRRFSLL SFIALLAYFA FLASAEHHVH QFVITPTPVK RLCRTHQSIT    50
VNGQYPGPTL VVRNGDSLAI TVINRARYNI SIHWHGIRQL RNPWADGPEY 100
ITQCPIRPGQ TYTYRFKIED QEGTLWWHAH SRWLRATVYG ALIIYPRLGS 150
PYPFSMPKRD IPILLGEWWD RNPMDVLKQA QFTGAAANVS DAYTINGQPG 200
DLYRCSRAGT IRFPIFPGET VQLRVINAGM NQELFFSVAN HQFTVVETDS 250
AYTKPFTTNV IMIGPGQTTN VLLTANQRPG RYYMAARAYN SANAPFDNTT 300
TTAILQYVNA PTRRGRGRGQ IAPVFPVLPG FNDTATATAF TNRLRYWKRA 350
PVPQQVDENL FFTVGLGLIN CANPNSPRCQ GPNGTRFAAS MNNMSFVLPR 400
SNSVMQAYYQ GTPGIFTTDF PPVPPVQFDY TGNVSRGLWQ PIKGTKAYKL 450
KYKSNVQIVL QDTSIVTPEN HPMHLHGYQF YVVGSGFGNF NPRTDPARFN 500
LFDPPERNTI GTPPGGWVAI RFVADNPGAW FMHCHIDSHL GWGLAMVFLV 550
ENGRGQLQSV QAPPLDLPRC 570
Length:570
Mass (Da):64,027
Last modified:April 3, 2007 - v2
Checksum:i48520C684D7B2DA3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC002338 Genomic DNA. Translation: AAC16927.1.
AC004165 Genomic DNA. Translation: AAM14916.1.
CP002685 Genomic DNA. Translation: AEC08358.1.
AK221241 mRNA. Translation: BAD93858.1.
PIRiT00579.
RefSeqiNP_180580.1. NM_128574.3.
UniGeneiAt.27864.

Genome annotation databases

EnsemblPlantsiAT2G30210.1; AT2G30210.1; AT2G30210.
GeneIDi817571.
KEGGiath:AT2G30210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC002338 Genomic DNA. Translation: AAC16927.1 .
AC004165 Genomic DNA. Translation: AAM14916.1 .
CP002685 Genomic DNA. Translation: AEC08358.1 .
AK221241 mRNA. Translation: BAD93858.1 .
PIRi T00579.
RefSeqi NP_180580.1. NM_128574.3.
UniGenei At.27864.

3D structure databases

ProteinModelPortali Q56YT0.
SMRi Q56YT0. Positions 43-549.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q56YT0.
PRIDEi Q56YT0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G30210.1 ; AT2G30210.1 ; AT2G30210 .
GeneIDi 817571.
KEGGi ath:AT2G30210.

Organism-specific databases

TAIRi AT2G30210.

Phylogenomic databases

eggNOGi COG2132.
HOGENOMi HOG000241916.
InParanoidi Q56YT0.
OMAi RYNISIH.
PhylomeDBi Q56YT0.

Enzyme and pathway databases

BioCyci ARA:AT2G30210-MONOMER.

Gene expression databases

Genevestigatori Q56YT0.

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 3 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 391-570.
    Strain: cv. Columbia.
  4. "Gene structure and molecular analysis of the laccase-like multicopper oxidase (LMCO) gene family in Arabidopsis thaliana."
    McCaig B.C., Meagher R.B., Dean J.F.D.
    Planta 221:619-636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  5. "Mutant identification and characterization of the laccase gene family in Arabidopsis."
    Cai X., Davis E.J., Ballif J., Liang M., Bushman E., Haroldsen V., Torabinejad J., Wu Y.
    J. Exp. Bot. 57:2563-2569(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiLAC3_ARATH
AccessioniPrimary (citable) accession number: Q56YT0
Secondary accession number(s): O22917
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 14, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi