Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Glutamate decarboxylase 2

Gene

GAD2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate decarboxylase 2Imported
Submitted name:
Putative uncharacterized protein At1g65960Imported
Gene namesi
Name:GAD2Imported
Ordered Locus Names:At1g65960Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G65960.

PTM / Processingi

Proteomic databases

PRIDEiQ56W28.

Expressioni

Gene expression databases

ExpressionAtlasiQ56W28. baseline and differential.
GenevestigatoriQ56W28.

Structurei

3D structure databases

ProteinModelPortaliQ56W28.
SMRiQ56W28. Positions 1-318.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q56W28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAGLAFKRK WQNKRKAEGK PYDKPNIVTG ANVQVCWEKF ARYFEVELKE
60 70 80 90 100
VNLSEGYYVM DPDKAAEMVD ENTICVAAIL GSTLNGEFED VKRLNDLLVK
110 120 130 140 150
KNEETGWNTP IHVDAASGGF IAPFIYPELE WDFRLPLVKS INVSGHKYGL
160 170 180 190 200
VYAGIGWVVW RAAEDLPEEL IFHINYLGAD QPTFTLNFSK GSSQIIAQYY
210 220 230 240 250
QLIRLGFEGY KNVMENCIEN MVVLKEGIEK TERFNIVSKD QGVPVVAFSL
260 270 280 290 300
KDHSFHNEFE ISEMLRRFGW IVPAYTMPAD AQHITVLRVV IREDFSRTLA
310 320 330 340 350
ERLVADISKV LHELDTLPSK ISKKMGIEGI AENVKEKKME KEILMEVIVG
360
WRKFVKERKK MNGVC
Length:365
Mass (Da):41,752
Last modified:May 10, 2005 - v1
Checksum:i453EF3409DABB0E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002684 Genomic DNA. Translation: AEE34444.1.
AK222191 mRNA. Translation: BAD95332.1.
AK222219 mRNA. Translation: BAD95387.1.
RefSeqiNP_176771.2. NM_105268.6.
UniGeneiAt.19149.
At.20543.
At.24993.
At.66846.

Genome annotation databases

EnsemblPlantsiAT1G65960.1; AT1G65960.1; AT1G65960.
GeneIDi842908.
KEGGiath:AT1G65960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002684 Genomic DNA. Translation: AEE34444.1.
AK222191 mRNA. Translation: BAD95332.1.
AK222219 mRNA. Translation: BAD95387.1.
RefSeqiNP_176771.2. NM_105268.6.
UniGeneiAt.19149.
At.20543.
At.24993.
At.66846.

3D structure databases

ProteinModelPortaliQ56W28.
SMRiQ56W28. Positions 1-318.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ56W28.

Protocols and materials databases

DNASUi842908.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G65960.1; AT1G65960.1; AT1G65960.
GeneIDi842908.
KEGGiath:AT1G65960.

Organism-specific databases

TAIRiAT1G65960.

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.

Gene expression databases

ExpressionAtlasiQ56W28. baseline and differential.
GenevestigatoriQ56W28.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. ColumbiaImported.
  2. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. TAIR
    Swarbreck D., Lamesch P., Wilks C., Huala E.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. The Arabidopsis Information Resource (TAIR)
    Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. ColumbiaImported.

Entry informationi

Entry nameiQ56W28_ARATH
AccessioniPrimary (citable) accession number: Q56W28
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 1, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.