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Protein

60S ribosomal protein L35a

Gene

RPL35A

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation (By similarity). The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L35a
Gene namesi
Name:RPL35A
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:53601 RPL35A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002401511 – 11060S ribosomal protein L35aAdd BLAST110

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei8N6-acetyllysineBy similarity1
Modified residuei63N6-acetyllysine; alternateBy similarity1
Modified residuei63N6-succinyllysine; alternateBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ56JY1
PeptideAtlasiQ56JY1
PRIDEiQ56JY1

Expressioni

Gene expression databases

BgeeiENSBTAG00000014208

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000018888

Structurei

3D structure databases

ProteinModelPortaliQ56JY1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0887 Eukaryota
COG2451 LUCA
GeneTreeiENSGT00390000016972
HOGENOMiHOG000195636
HOVERGENiHBG054581
InParanoidiQ56JY1
KOiK02917
OMAiVRAIWGK
OrthoDBiEOG091G112U
TreeFamiTF300104

Family and domain databases

Gene3Di2.40.10.190, 1 hit
HAMAPiMF_00573 Ribosomal_L35Ae, 1 hit
InterProiView protein in InterPro
IPR038661 L35A_sf
IPR001780 Ribosomal_L35A
IPR018266 Ribosomal_L35Ae_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR10902 PTHR10902, 1 hit
PfamiView protein in Pfam
PF01247 Ribosomal_L35Ae, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012670 Ribosomal_L35Ae, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
PROSITEiView protein in PROSITE
PS01105 RIBOSOMAL_L35AE, 1 hit

Sequencei

Sequence statusi: Complete.

Q56JY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV
60 70 80 90 100
YKAKNNTVTP GGKPNKTRVI WGKITRAHGN SGMVRAKFRS NLPAKAIGHR
110
IRVMLYPSRI
Length:110
Mass (Da):12,552
Last modified:May 10, 2005 - v1
Checksum:iF32E4A26B1E64278
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY911347 mRNA Translation: AAW82114.1
BC111654 mRNA Translation: AAI11655.1
RefSeqiNP_001020492.1, NM_001025321.3
XP_005201446.1, XM_005201389.1
XP_005201447.1, XM_005201390.2
UniGeneiBt.15384
Bt.65591

Genome annotation databases

EnsembliENSBTAT00000018888; ENSBTAP00000018888; ENSBTAG00000014208
GeneIDi506768
KEGGibta:506768

Similar proteinsi

Entry informationi

Entry nameiRL35A_BOVIN
AccessioniPrimary (citable) accession number: Q56JY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health