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Protein

40S ribosomal protein S24

Gene

RPS24

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-BTA-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-BTA-72649. Translation initiation complex formation.
R-BTA-72689. Formation of a pool of free 40S subunits.
R-BTA-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-BTA-72702. Ribosomal scanning and start codon recognition.
R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S24
Gene namesi
Name:RPS24
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002310101 – 13140S ribosomal protein S24Add BLAST131

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei9PhosphothreonineBy similarity1
Cross-linki37Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiQ56JU9.
PeptideAtlasiQ56JU9.
PRIDEiQ56JU9.

Expressioni

Gene expression databases

BgeeiENSBTAG00000013264.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000043937.

Structurei

3D structure databases

ProteinModelPortaliQ56JU9.
SMRiQ56JU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3424. Eukaryota.
COG2004. LUCA.
GeneTreeiENSGT00390000000153.
HOGENOMiHOG000186306.
HOVERGENiHBG000969.
InParanoidiQ56JU9.
KOiK02974.
OMAiTHFGGGR.
OrthoDBiEOG091G0WLL.
TreeFamiTF314134.

Family and domain databases

HAMAPiMF_00545. Ribosomal_S24e. 1 hit.
InterProiView protein in InterPro
IPR012678. Ribosomal_L23/L15e_core_dom_sf.
IPR001976. Ribosomal_S24e.
IPR018098. Ribosomal_S24e_CS.
PANTHERiPTHR10496. PTHR10496. 1 hit.
PfamiView protein in Pfam
PF01282. Ribosomal_S24e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006052. Ribosomal_S24e. 1 hit.
SUPFAMiSSF54189. SSF54189. 1 hit.
PROSITEiView protein in PROSITE
PS00529. RIBOSOMAL_S24E. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q56JU9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT
60 70 80 90 100
TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKHR LARHGLYEKK
110 120 130
KTSRKQRKER KNRMKKVRGT AKANVGAGKK K
Length:131
Mass (Da):15,197
Last modified:April 4, 2006 - v2
Checksum:i3190764D60A6DD57
GO
Isoform 2 (identifier: Q56JU9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-131: Missing.

Note: No experimental confirmation available.
Show »
Length:130
Mass (Da):15,069
Checksum:iE0764D60A6DD576E
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_017835131Missing in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY911383 mRNA. Translation: AAW82146.1.
BC103133 mRNA. Translation: AAI03134.1.
RefSeqiNP_001020510.1. NM_001025339.2. [Q56JU9-2]
XP_005226462.1. XM_005226405.3. [Q56JU9-1]
XP_005226463.1. XM_005226406.3. [Q56JU9-1]
UniGeneiBt.8015.

Genome annotation databases

EnsembliENSBTAT00000046662; ENSBTAP00000043937; ENSBTAG00000013264. [Q56JU9-2]
GeneIDi530464.
KEGGibta:530464.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiRS24_BOVIN
AccessioniPrimary (citable) accession number: Q56JU9
Secondary accession number(s): Q3SZ53
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: November 22, 2017
This is version 96 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families