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Q569W9

- Q569W9_MOUSE

UniProt

Q569W9 - Q569W9_MOUSE

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Protein
Submitted name:

Igh protein

Gene

Igh

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Igh proteinImported
Gene namesi
Name:IghImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ569W9.

Expressioni

Gene expression databases

GenevestigatoriQ569W9.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1NBZX-ray1.85B20-235[»]
1RUQX-ray1.86H26-235[»]
1RURX-ray1.50H26-235[»]
3OZ9X-ray1.60H127-238[»]
ProteinModelPortaliQ569W9.
SMRiQ569W9. Positions 20-464.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ569W9.

Family & Domainsi

Keywords - Domaini

Immunoglobulin domainSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q569W9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEWSCIFLFL LSVTAGVHSE VQLQQSGAEL VRPGSSVKLS CKTSGYTFTS
60 70 80 90 100
YYINWVKQRP GQGLEWIGHI YPGNGYTEYN EKFKGKATLT SDTSSSTAYM
110 120 130 140 150
QLRSLTSENS AIYFCARTGG YDGYFDYWGQ GTTITVSSAK TTAPSVYPLA
160 170 180 190 200
PVCGDTTGSS VTLGCLVKGY FPEPVTLTWN SGSLSSGVHT FPAVLQSDLY
210 220 230 240 250
TLSSSVTVTS STWPSQSITC NVAHPASSTK VDKKIEPRGP TIKPCPPCKC
260 270 280 290 300
PAPNLLGGPS VFIFPPKIKD VLMISLSPMV TCVVVDVSED DPDVQISWFV
310 320 330 340 350
NNVEVLTAQT QTHREDYNST LRVVSALPIQ HQDWMSGKEF KCKVNNKALP
360 370 380 390 400
APIERTISKP KGSVRAPQVY VLPPPEEEMT KKQVTLTCMV TDFMPEDIYV
410 420 430 440 450
EWTNNGKTEL NYKNTEPVLD SDGSYFMYSK LRVEKKNWVE RNSYSCSVVH
460
EGLHNHHTTK SFSRTPGK
Length:468
Mass (Da):51,666
Last modified:May 10, 2005 - v1
Checksum:i5BF6E527329F8461
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC092271 mRNA. Translation: AAH92271.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC092271 mRNA. Translation: AAH92271.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1NBZ X-ray 1.85 B 20-235 [» ]
1RUQ X-ray 1.86 H 26-235 [» ]
1RUR X-ray 1.50 H 26-235 [» ]
3OZ9 X-ray 1.60 H 127-238 [» ]
ProteinModelPortali Q569W9.
SMRi Q569W9. Positions 20-464.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I43.001.

Proteomic databases

PRIDEi Q569W9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG005814.

Miscellaneous databases

EvolutionaryTracei Q569W9.

Gene expression databases

Genevestigatori Q569W9.

Family and domain databases

Gene3Di 2.60.40.10. 4 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view ]
Pfami PF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen."
    Li Y., Urrutia M., Smith-Gill S.J., Mariuzza R.A.
    Biochemistry 42:11-22(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 20-235.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Czech IIImported.
    Tissue: Mammary tumor metastatized to lung. Tumor arose spontaneouslyImported.
  3. "Probing the antibody-catalyzed water-oxidation pathway at atomic resolution."
    Zhu X., Wentworth P., Wentworth A.D., Eschenmoser A., Lerner R.A., Wilson I.A.
    Proc. Natl. Acad. Sci. U.S.A. 101:2247-2252(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 26-235.
  4. "Crystal Structure of anti-gp41 Fab NC-1."
    Stanfield R.L., Calarese D.A., Jiang S., Wilson I.A.
    Submitted (SEP-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 127-238.

Entry informationi

Entry nameiQ569W9_MOUSE
AccessioniPrimary (citable) accession number: Q569W9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3