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Protein

Leucine-rich repeat-containing protein 14

Gene

Lrrc14

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 14
Gene namesi
Name:Lrrc14
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1560202. Lrrc14.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 493493Leucine-rich repeat-containing protein 14PRO_0000343682Add
BLAST

Proteomic databases

PaxDbiQ569B5.
PRIDEiQ569B5.

Expressioni

Gene expression databases

ExpressionAtlasiQ569B5. baseline.
GenevisibleiQ569B5. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021673.

Structurei

3D structure databases

ProteinModelPortaliQ569B5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati285 – 30723LRR 1Add
BLAST
Repeati310 – 33021LRR 2Add
BLAST
Repeati337 – 36024LRR 3Add
BLAST
Repeati366 – 38722LRR 4Add
BLAST
Repeati394 – 41421LRR 5Add
BLAST

Sequence similaritiesi

Belongs to the PRAME family. LRRC14 subfamily.Curated
Contains 5 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiENOG410IIBA. Eukaryota.
ENOG4111FCX. LUCA.
GeneTreeiENSGT00760000119028.
HOGENOMiHOG000113363.
HOVERGENiHBG052342.
InParanoidiQ569B5.
OMAiPILTRCT.
OrthoDBiEOG7JX346.
PhylomeDBiQ569B5.
TreeFamiTF332708.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR026292. LRRC14.
[Graphical view]
PANTHERiPTHR14224:SF9. PTHR14224:SF9. 1 hit.
PfamiPF13516. LRR_6. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q569B5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTLVFLSTR QVLQCQPAAC QALPLLPREL FPLLFKVAFM DKKTAVLREL
60 70 80 90 100
VHTWPFPLLS FQQLLQECAH CSRALLQERL STESMQAVIL GLTARIHARE
110 120 130 140 150
AEAGTQPVCR KHTLRVLDMT GLLDDGVEQD PGTMSMWDCT AAVARTCIAQ
160 170 180 190 200
QQVGTAKPGL SPVPVEIRVD LRVNRASYTF LREALQSSVD SLLRLCCRDL
210 220 230 240 250
RAEDLPMRNT VALLQLLDAG CLRRIDLRFN NLGLRGLSVI IPHVARFQHL
260 270 280 290 300
ASLRLHYVHG DSRQPSVDGE DNFRYFLAQM GRFICLRELS IGSSLLSGRL
310 320 330 340 350
DQLLSTLQRP LESLELAFCA LLPEDLRFLA QSSHAAHLKK LDLSGNDLSG
360 370 380 390 400
NQLTPFQGLL QAVAATLLHL ELTECQIADA QLLATLPTLT RCASLRYLGL
410 420 430 440 450
YGNPLSMAGL KELLRDSVIQ AELRTVVHPF PVDCYEGLPW PPPASVLLEA
460 470 480 490
SINEEKFARV EAELHQLLLA SGRAHVLWTT DIYGRLAADY FNL
Length:493
Mass (Da):54,915
Last modified:May 10, 2005 - v1
Checksum:i6810AE5070F45B08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473950 Genomic DNA. Translation: EDM15941.1.
CH473950 Genomic DNA. Translation: EDM15942.1.
BC092583 mRNA. Translation: AAH92583.1.
RefSeqiNP_001019525.1. NM_001024354.1.
XP_006241924.1. XM_006241862.2.
XP_006241927.1. XM_006241865.1.
UniGeneiRn.138067.

Genome annotation databases

EnsembliENSRNOT00000021673; ENSRNOP00000021673; ENSRNOG00000016128.
GeneIDi500900.
KEGGirno:500900.
UCSCiRGD:1560202. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473950 Genomic DNA. Translation: EDM15941.1.
CH473950 Genomic DNA. Translation: EDM15942.1.
BC092583 mRNA. Translation: AAH92583.1.
RefSeqiNP_001019525.1. NM_001024354.1.
XP_006241924.1. XM_006241862.2.
XP_006241927.1. XM_006241865.1.
UniGeneiRn.138067.

3D structure databases

ProteinModelPortaliQ569B5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021673.

Proteomic databases

PaxDbiQ569B5.
PRIDEiQ569B5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000021673; ENSRNOP00000021673; ENSRNOG00000016128.
GeneIDi500900.
KEGGirno:500900.
UCSCiRGD:1560202. rat.

Organism-specific databases

CTDi9684.
RGDi1560202. Lrrc14.

Phylogenomic databases

eggNOGiENOG410IIBA. Eukaryota.
ENOG4111FCX. LUCA.
GeneTreeiENSGT00760000119028.
HOGENOMiHOG000113363.
HOVERGENiHBG052342.
InParanoidiQ569B5.
OMAiPILTRCT.
OrthoDBiEOG7JX346.
PhylomeDBiQ569B5.
TreeFamiTF332708.

Miscellaneous databases

PROiQ569B5.

Gene expression databases

ExpressionAtlasiQ569B5. baseline.
GenevisibleiQ569B5. RN.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR026292. LRRC14.
[Graphical view]
PANTHERiPTHR14224:SF9. PTHR14224:SF9. 1 hit.
PfamiPF13516. LRR_6. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown Norway.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.

Entry informationi

Entry nameiLRC14_RAT
AccessioniPrimary (citable) accession number: Q569B5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: May 10, 2005
Last modified: June 8, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.