Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Hemin-binding periplasmic protein HmuT

Gene

hmuT

Organism
Yersinia pestis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Part of the binding-protein-dependent transport system for hemin.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Iron transport, Transport

Keywords - Ligandi

Iron

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3325-MONOMER.
YPES214092:GKDD-280-MONOMER.

Protein family/group databases

TCDBi3.A.1.14.5. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Hemin-binding periplasmic protein HmuT
Gene namesi
Name:hmuT
Ordered Locus Names:YPO0281, y0541, YP_0436
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 279254Hemin-binding periplasmic protein HmuTPRO_0000021447Add
BLAST

Proteomic databases

PRIDEiQ56991.

Interactioni

Protein-protein interaction databases

DIPiDIP-60002N.
IntActiQ56991. 1 interaction.
STRINGi187410.y0541.

Structurei

Secondary structure

1
279
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi29 – 335Combined sources
Helixi34 – 429Combined sources
Helixi46 – 483Combined sources
Beta strandi49 – 524Combined sources
Helixi60 – 645Combined sources
Helixi76 – 805Combined sources
Beta strandi85 – 906Combined sources
Helixi96 – 1049Combined sources
Beta strandi108 – 1125Combined sources
Helixi118 – 13215Combined sources
Helixi135 – 15016Combined sources
Beta strandi160 – 1656Combined sources
Beta strandi168 – 1703Combined sources
Beta strandi173 – 1753Combined sources
Beta strandi177 – 1793Combined sources
Helixi180 – 1878Combined sources
Beta strandi191 – 1933Combined sources
Beta strandi198 – 2025Combined sources
Helixi205 – 2117Combined sources
Beta strandi214 – 2196Combined sources
Helixi220 – 2267Combined sources
Helixi229 – 2346Combined sources
Helixi238 – 2403Combined sources
Helixi242 – 2454Combined sources
Beta strandi249 – 2524Combined sources
Helixi254 – 2585Combined sources
Helixi264 – 27714Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3MD9X-ray1.50A/B26-279[»]
ProteinModelPortaliQ56991.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ56991.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 279252Fe/B12 periplasmic-bindingPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 Fe/B12 periplasmic-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107R4I. Bacteria.
COG4558. LUCA.
HOGENOMiHOG000219574.
KOiK02016.
OMAiRDSTSQW.
OrthoDBiEOG6JTC6W.

Family and domain databases

InterProiIPR002491. ABC_transptr_periplasmic_BD.
[Graphical view]
PfamiPF01497. Peripla_BP_2. 1 hit.
[Graphical view]
PROSITEiPS50983. FE_B12_PBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q56991-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLRLLSLPF ILSLCAPLLP LNTLAAERIV TIGGDVTEIA YALGAGDEIV
60 70 80 90 100
ARDSTSQQPQ AAQKLPDVGY MRTLNAEGIL AMKPTMLLVS ELAQPSLVLT
110 120 130 140 150
QIASSGVNVV TVPGQTTPES VAMKINAVAT ALHQTEKGQK LIEDYQQRLA
160 170 180 190 200
AVNKTPLPVK VLFVMSHGGL TPMAAGQNTA ADAMIRAAGG SNAMQGFSRY
210 220 230 240 250
RPLSQEGVIA SAPDLLLITT DGVKALGSSE NIWKLPGMAL TPAGKHKRLL
260 270
VVDDMALLGF GLETPQVLAQ LREKMEQMQ
Length:279
Mass (Da):29,574
Last modified:May 30, 2000 - v2
Checksum:i190547D960C93763
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60647 Genomic DNA. Translation: AAC64868.1.
AL590842 Genomic DNA. Translation: CAL18967.1.
AE009952 Genomic DNA. Translation: AAM84129.1.
AE017042 Genomic DNA. Translation: AAS60707.1.
PIRiAE0035.
T12071.
RefSeqiWP_002209060.1. NZ_LQAY01000008.1.
YP_002345363.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM84129; AAM84129; y0541.
AAS60707; AAS60707; YP_0436.
GeneIDi1173127.
KEGGiype:YPO0281.
ypj:CH55_3479.
ypk:y0541.
ypl:CH46_631.
ypm:YP_0436.
ypv:BZ15_3288.
ypw:CH59_1580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60647 Genomic DNA. Translation: AAC64868.1.
AL590842 Genomic DNA. Translation: CAL18967.1.
AE009952 Genomic DNA. Translation: AAM84129.1.
AE017042 Genomic DNA. Translation: AAS60707.1.
PIRiAE0035.
T12071.
RefSeqiWP_002209060.1. NZ_LQAY01000008.1.
YP_002345363.1. NC_003143.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3MD9X-ray1.50A/B26-279[»]
ProteinModelPortaliQ56991.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60002N.
IntActiQ56991. 1 interaction.
STRINGi187410.y0541.

Protein family/group databases

TCDBi3.A.1.14.5. the atp-binding cassette (abc) superfamily.

Proteomic databases

PRIDEiQ56991.

Protocols and materials databases

DNASUi1145488.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM84129; AAM84129; y0541.
AAS60707; AAS60707; YP_0436.
GeneIDi1173127.
KEGGiype:YPO0281.
ypj:CH55_3479.
ypk:y0541.
ypl:CH46_631.
ypm:YP_0436.
ypv:BZ15_3288.
ypw:CH59_1580.

Phylogenomic databases

eggNOGiENOG4107R4I. Bacteria.
COG4558. LUCA.
HOGENOMiHOG000219574.
KOiK02016.
OMAiRDSTSQW.
OrthoDBiEOG6JTC6W.

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3325-MONOMER.
YPES214092:GKDD-280-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ56991.

Family and domain databases

InterProiIPR002491. ABC_transptr_periplasmic_BD.
[Graphical view]
PfamiPF01497. Peripla_BP_2. 1 hit.
[Graphical view]
PROSITEiPS50983. FE_B12_PBP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem-protein complexes as iron sources."
    Hornung J.M., Jones H.A., Perry R.D.
    Mol. Microbiol. 20:725-739(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: KIM6.
  2. Hornung J.M., Jones H.A., Bertolino V.J., Perry R.D.
    Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  5. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiHMUT_YERPE
AccessioniPrimary (citable) accession number: Q56991
Secondary accession number(s): Q0WK25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: July 6, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.