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Q566E5 (KDEL2_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
KDEL motif-containing protein 2
Gene names
Name:Kdelc2
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length508 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Endoplasmic reticulum lumen Potential.

Sequence similarities

Belongs to the KDELC family.

Contains 1 filamin repeat.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 508484KDEL motif-containing protein 2
PRO_0000247197

Regions

Repeat25 – 134110Filamin
Motif505 – 5084Prevents secretion from ER Potential

Amino acid modifications

Glycosylation3071N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict4961R → C in AAI00618. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q566E5 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: E04AB38138CC5DF9

FASTA50858,701
        10         20         30         40         50         60 
MLGVRRALLL PPLQLALLVA AGTGARVSAP RSLAWGPGLH ADAVLPVRYF FLQSVDSDGR 

        70         80         90        100        110        120 
NFTSSPPGQT QFKVVVKSLS PKELVRIYVP KPLDRNDGTF LVRYRMHETV HEGLKIEILY 

       130        140        150        160        170        180 
GGEHVAQSPY ILKGPVYHEY CDCPEDDPQA WQKTLSCPAN EPQIEQDFIS FPSINLQQML 

       190        200        210        220        230        240 
KEVPKRFGDE RGAIVHYTIL NNHIYRRSLG KYTDFKMFSD EILLSLARKV TLPDLEFYIN 

       250        260        270        280        290        300 
LGDWPLEHRK VNDTPGPIPI ISWCGSLDSR DIILPTYDVT HSTLEAMRGV TNDLLSVQGN 

       310        320        330        340        350        360 
TGPSWINKTE KAFFRGRDSR EERLQLVLLS KENPQLLDAG ITGYFFFQEK EKELGKAKLM 

       370        380        390        400        410        420 
GFFDFFKYKY QVNVDGTVAA YRYPYLMLGD SLVLKQESPY YEHFYVELRP WKHYVPIKRN 

       430        440        450        460        470        480 
LSDLLEKVKW AKENDEEAKR IAKEGQLTAR DLLQPPRLYC YYYRVLQKYA ERQVSKPMIR 

       490        500 
DGMERVPQPD DSTSVRQCHR KRPEREEL 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain and Prostate.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC093594 mRNA. Translation: AAH93594.1.
BC100617 mRNA. Translation: AAI00618.1.
RefSeqNP_001020294.3. NM_001025123.3.
UniGeneRn.98686.

3D structure databases

ProteinModelPortalQ566E5.
SMRQ566E5. Positions 22-134.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGT90. Glycosyltransferase Family 90.

Proteomic databases

PaxDbQ566E5.
PRIDEQ566E5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000009497; ENSRNOP00000009497; ENSRNOG00000007177.
GeneID315664.
KEGGrno:315664.
UCSCRGD:1562027. rat.

Organism-specific databases

CTD143888.
RGD1562027. Kdelc2.

Phylogenomic databases

eggNOGNOG248922.
GeneTreeENSGT00530000063132.
HOGENOMHOG000286007.
HOVERGENHBG081852.
InParanoidQ566E5.
OMAPVRYFYL.
OrthoDBEOG7XDBG0.
PhylomeDBQ566E5.
TreeFamTF323280.

Gene expression databases

GenevestigatorQ566E5.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
InterProIPR017868. Filamin/ABP280_repeat-like.
IPR001298. Filamin/ABP280_rpt.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR006598. LipoPS_modifying.
[Graphical view]
PfamPF00630. Filamin. 1 hit.
PF05686. Glyco_transf_90. 1 hit.
[Graphical view]
SMARTSM00672. CAP10. 1 hit.
SM00557. IG_FLMN. 1 hit.
[Graphical view]
SUPFAMSSF81296. SSF81296. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS50194. FILAMIN_REPEAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio669617.
PROQ566E5.

Entry information

Entry nameKDEL2_RAT
AccessionPrimary (citable) accession number: Q566E5
Secondary accession number(s): Q497C8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: May 10, 2005
Last modified: April 16, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families