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Q56693 (PABC_VIBHA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aminodeoxychorismate lyase

EC=4.1.3.38
Alternative name(s):
4-amino-4-deoxychorismate lyase
Short name=ADC lyase
Short name=ADCL
Gene names
Name:pabC
OrganismVibrio harveyi (Beneckea harveyi)
Taxonomic identifier669 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length271 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate By similarity.

Catalytic activity

4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Cofactor biosynthesis; tetrahydrofolate biosynthesis; 4-aminobenzoate from chorismate: step 2/2.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 271271Aminodeoxychorismate lyase
PRO_0000103307

Amino acid modifications

Modified residue1401N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q56693 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 3AE5BEB9F398D1CD

FASTA27129,958
        10         20         30         40         50         60 
MFWVNGLPQT HVPLGDRSFQ YGDGCFSTIK TKKGQLEHWQ AHVERMEACL TTLQIPFPDW 

        70         80         90        100        110        120 
RTVLDWAMSA TLKDESAGIK IHISRGCGGR GYSPSGVEGP VVTISNFSFP AHYLAWQERG 

       130        140        150        160        170        180 
VQLGVCETRL GIQPLLAGHK HNNRIEQVLA KAEIDGTEFA DAVTLNVQNH VIETTMANLF 

       190        200        210        220        230        240 
WVKDEKVFTP GLCLSGVAGV MRRKVLEYLQ SEGYSVQVAD FTLTDLLDAD EVWMCNSLLG 

       250        260        270 
VAPVSGISAP ENKIDFPIGK LTRRLQGNLN T 

« Hide

References

[1]"Isolation of Vibrio harveyi acyl carrier protein and the fabG, acpP, and fabF genes involved in fatty acid biosynthesis."
Shen Z., Byers D.M.
J. Bacteriol. 178:571-573(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 33843 / 392 / MAV.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U39441 Genomic DNA. Translation: AAC43592.1.
PIRT12054.

3D structure databases

ProteinModelPortalQ56693.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00077; UER00150.

Family and domain databases

InterProIPR017824. Aminodeoxychorismate_lyase_IV.
IPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
[Graphical view]
PANTHERPTHR11825. PTHR11825. 1 hit.
PfamPF01063. Aminotran_4. 1 hit.
[Graphical view]
SUPFAMSSF56752. SSF56752. 1 hit.
TIGRFAMsTIGR03461. pabC_Proteo. 1 hit.
PROSITEPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePABC_VIBHA
AccessionPrimary (citable) accession number: Q56693
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: December 11, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways