Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q56693

- PABC_VIBHA

UniProt

Q56693 - PABC_VIBHA

Protein

Aminodeoxychorismate lyase

Gene

pabC

Organism
Vibrio harveyi (Beneckea harveyi)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate By similarity.By similarity

    Catalytic activityi

    4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate.

    Cofactori

    Pyridoxal phosphate.By similarity

    Pathwayi

    GO - Molecular functioni

    1. 4-amino-4-deoxychorismate lyase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. folic acid biosynthetic process Source: UniProtKB-KW
    2. tetrahydrofolate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Folate biosynthesis

    Keywords - Ligandi

    Pyridoxal phosphate

    Enzyme and pathway databases

    UniPathwayiUPA00077; UER00150.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aminodeoxychorismate lyase (EC:4.1.3.38)
    Alternative name(s):
    4-amino-4-deoxychorismate lyase
    Short name:
    ADC lyase
    Short name:
    ADCL
    Gene namesi
    Name:pabC
    OrganismiVibrio harveyi (Beneckea harveyi)
    Taxonomic identifieri669 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 271271Aminodeoxychorismate lyasePRO_0000103307Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei140 – 1401N6-(pyridoxal phosphate)lysineBy similarity

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ56693.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR017824. Aminodeoxychorismate_lyase_IV.
    IPR001544. Aminotrans_IV.
    IPR018300. Aminotrans_IV_CS.
    [Graphical view]
    PANTHERiPTHR11825. PTHR11825. 1 hit.
    PfamiPF01063. Aminotran_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF56752. SSF56752. 1 hit.
    TIGRFAMsiTIGR03461. pabC_Proteo. 1 hit.
    PROSITEiPS00770. AA_TRANSFER_CLASS_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q56693-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFWVNGLPQT HVPLGDRSFQ YGDGCFSTIK TKKGQLEHWQ AHVERMEACL    50
    TTLQIPFPDW RTVLDWAMSA TLKDESAGIK IHISRGCGGR GYSPSGVEGP 100
    VVTISNFSFP AHYLAWQERG VQLGVCETRL GIQPLLAGHK HNNRIEQVLA 150
    KAEIDGTEFA DAVTLNVQNH VIETTMANLF WVKDEKVFTP GLCLSGVAGV 200
    MRRKVLEYLQ SEGYSVQVAD FTLTDLLDAD EVWMCNSLLG VAPVSGISAP 250
    ENKIDFPIGK LTRRLQGNLN T 271
    Length:271
    Mass (Da):29,958
    Last modified:November 1, 1996 - v1
    Checksum:i3AE5BEB9F398D1CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U39441 Genomic DNA. Translation: AAC43592.1.
    PIRiT12054.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U39441 Genomic DNA. Translation: AAC43592.1 .
    PIRi T12054.

    3D structure databases

    ProteinModelPortali Q56693.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00077 ; UER00150 .

    Family and domain databases

    InterProi IPR017824. Aminodeoxychorismate_lyase_IV.
    IPR001544. Aminotrans_IV.
    IPR018300. Aminotrans_IV_CS.
    [Graphical view ]
    PANTHERi PTHR11825. PTHR11825. 1 hit.
    Pfami PF01063. Aminotran_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56752. SSF56752. 1 hit.
    TIGRFAMsi TIGR03461. pabC_Proteo. 1 hit.
    PROSITEi PS00770. AA_TRANSFER_CLASS_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation of Vibrio harveyi acyl carrier protein and the fabG, acpP, and fabF genes involved in fatty acid biosynthesis."
      Shen Z., Byers D.M.
      J. Bacteriol. 178:571-573(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 33843 / 392 / MAV.

    Entry informationi

    Entry nameiPABC_VIBHA
    AccessioniPrimary (citable) accession number: Q56693
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3