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Protein

Probable sucrose-6-phosphate hydrolase

Gene
N/A
Organism
Vibrio cholerae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enables the bacterium to metabolize sucrose as a sole carbon source.By similarity

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.PROSITE-ProRule annotation

Pathwayi: sucrose metabolism

This protein is involved in the pathway sucrose metabolism, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway sucrose metabolism and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei108PROSITE-ProRule annotation1
Binding sitei124SubstrateBy similarity1
Binding sitei283SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Enzyme and pathway databases

UniPathwayiUPA00238.

Protein family/group databases

CAZyiGH32. Glycoside Hydrolase Family 32.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable sucrose-6-phosphate hydrolase (EC:3.2.1.26)
Short name:
Sucrase
Alternative name(s):
Invertase
OrganismiVibrio cholerae
Taxonomic identifieri666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003412981 – 546Probable sucrose-6-phosphate hydrolaseAdd BLAST546

Structurei

3D structure databases

ProteinModelPortaliQ56660.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni105 – 108Substrate bindingBy similarity4
Regioni167 – 168Substrate bindingBy similarity2
Regioni228 – 229Substrate bindingBy similarity2

Sequence similaritiesi

Belongs to the glycosyl hydrolase 32 family.Curated

Phylogenomic databases

eggNOGiENOG4108HKT. Bacteria.
COG1621. LUCA.

Family and domain databases

Gene3Di2.115.10.20. 1 hit.
InterProiView protein in InterPro
IPR013320. ConA-like_dom_sf.
IPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
IPR023296. Glyco_hydro_beta-prop_sf.
IPR006232. Suc6P_hydrolase.
PfamiView protein in Pfam
PF08244. Glyco_hydro_32C. 1 hit.
PF00251. Glyco_hydro_32N. 1 hit.
SMARTiView protein in SMART
SM00640. Glyco_32. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF75005. SSF75005. 1 hit.
TIGRFAMsiTIGR01322. scrB_fam. 1 hit.
PROSITEiView protein in PROSITE
PS00609. GLYCOSYL_HYDROL_F32. 1 hit.

Sequencei

Sequence statusi: Complete.

Q56660-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLDTQLELA GGINNVTRIL APQGQVVLAL KHPPHAPHLP DDVSLQSVLG
60 70 80 90 100
EWQLSVQRTA EVSDQQLATI GKAISERQKL ETLPYQTALD CPYRPLWHIS
110 120 130 140 150
PPQGLLNDPN GFIYHQGEYH LFYQWHPFVC EHKDKYWVHL KSLDLVHWQW
160 170 180 190 200
QSVALTPSDW FDSHGVFSGH AVSHQQDLWL FYTGNTRLGV DRQRQTMQCA
210 220 230 240 250
ARMNANGEFE KLGPVIRCLP EGVTEHIRDP KVIYTQGKWH MLLGAQTLAH
260 270 280 290 300
QGRLAVYHSD DLLHWHFDKL YGDELGNYGY MWECPDWFEL QGEAFFVFGP
310 320 330 340 350
QGIASANPHH TIEHQNRIFR ATQNAQGEIA LLQGWPLDEG FDFYAPQTAQ
360 370 380 390 400
TTDGRRVLCG WMGLPDETQH PSCDQGWIHQ LTALRELEWR EGKIYQHPLR
410 420 430 440 450
ELDTLRSEPH TLLLSDTVTE LKAKSFDVQV TLPWGCQLRL MQNAQYCVTL
460 470 480 490 500
TLDAENRLLR LDRSATQIRQ GDTIRELKLD SPTVELRILA DQSSLEIFIN
510 520 530 540
QGEHVMTSRI FTPLDATGIS LHGASVDAKL YYMAPASAPF NLEVNV
Length:546
Mass (Da):62,334
Last modified:November 1, 1996 - v1
Checksum:iBC6FF116B1A40CB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M74035 Genomic DNA. Translation: AAA27560.1.

Similar proteinsi

Entry informationi

Entry nameiSCRB_VIBCL
AccessioniPrimary (citable) accession number: Q56660
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 1, 1996
Last modified: November 22, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families