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Protein

V-type ATP synthase beta chain

Gene

atpB

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-1306-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
V-type ATP synthase beta chain
Alternative name(s):
V-ATPase subunit B
Gene namesi
Name:atpB
Ordered Locus Names:TTHA1272
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 478478V-type ATP synthase beta chainPRO_0000144682Add
BLAST

Proteomic databases

PRIDEiQ56404.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
atpAQ564032EBI-7260036,EBI-7260009

Protein-protein interaction databases

IntActiQ56404. 1 interaction.
MINTiMINT-7297946.
STRINGi300852.TTHA1272.

Structurei

Secondary structure

1
478
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi11 – 155Combined sources
Beta strandi18 – 236Combined sources
Beta strandi32 – 365Combined sources
Beta strandi42 – 6120Combined sources
Beta strandi68 – 703Combined sources
Beta strandi72 – 798Combined sources
Beta strandi81 – 844Combined sources
Turni87 – 904Combined sources
Beta strandi91 – 944Combined sources
Beta strandi101 – 1033Combined sources
Beta strandi109 – 1135Combined sources
Helixi121 – 1233Combined sources
Helixi136 – 1394Combined sources
Beta strandi152 – 1554Combined sources
Helixi160 – 17011Combined sources
Helixi175 – 1784Combined sources
Beta strandi187 – 19610Combined sources
Helixi198 – 21013Combined sources
Helixi213 – 2164Combined sources
Beta strandi217 – 2237Combined sources
Helixi229 – 24719Combined sources
Beta strandi252 – 2587Combined sources
Helixi260 – 27213Combined sources
Turni273 – 2753Combined sources
Helixi280 – 2823Combined sources
Helixi287 – 2959Combined sources
Beta strandi307 – 31610Combined sources
Helixi324 – 3329Combined sources
Beta strandi333 – 3397Combined sources
Helixi341 – 3455Combined sources
Turni354 – 3563Combined sources
Helixi362 – 3643Combined sources
Turni368 – 3703Combined sources
Helixi375 – 39521Combined sources
Beta strandi397 – 3993Combined sources
Helixi407 – 4104Combined sources
Helixi413 – 4208Combined sources
Turni421 – 4233Combined sources
Helixi432 – 44312Combined sources
Helixi448 – 4503Combined sources
Helixi456 – 4627Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3A5CX-ray4.51D/E/F/L/M/N1-478[»]
3A5DX-ray4.80D/E/F/L/M/N1-478[»]
3GQBX-ray2.80B/D1-464[»]
3J0Jelectron microscopy9.70D/E/F1-478[»]
3W3AX-ray3.90D/E/F/L/M/N7-463[»]
5GARelectron microscopy6.40D/E/F7-463[»]
5GASelectron microscopy9.50D/E/F7-463[»]
ProteinModelPortaliQ56404.
SMRiQ56404. Positions 16-463.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ56404.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.Curated

Phylogenomic databases

eggNOGiENOG4108JIP. Bacteria.
COG1156. LUCA.
HOGENOMiHOG000165320.
KOiK02118.
OMAiWRERRYL.
PhylomeDBiQ56404.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00310. ATP_synth_B_arch. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039114. V-ATPsynth_beta/V-ATPase_B. 1 hit.
SUPFAMiSSF47917. SSF47917. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q56404-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLLKKEYTG ITYISGPLLF VENAKDLAYG AIVDIKDGTG RVRGGQVIEV
60 70 80 90 100
SEEYAVIQVF EETTGLDLAT TSVSLVEDVA RLGVSKEMLG RRFNGIGKPI
110 120 130 140 150
DGLPPITPEK RLPITGLPLN PVARRKPEQF IQTGISTIDV MNTLVRGQKL
160 170 180 190 200
PIFSGSGLPA NEIAAQIARQ ATVRPDLSGE GEKEEPFAVV FAAMGITQRE
210 220 230 240 250
LSYFIQEFER TGALSRSVLF LNKADDPTIE RILTPRMALT VAEYLAFEHD
260 270 280 290 300
YHVLVILTDM TNYCEALREI GAAREEIPGR RGYPGYMYTD LATIYERAGV
310 320 330 340 350
VEGKKGSVTQ IPILSMPDDD RTHPIPDLTG YITEGQIQLS RELHRKGIYP
360 370 380 390 400
PIDPLPSLSR LMNNGVGKGK TREDHKQVSD QLYSAYANGV DIRKLVAIIG
410 420 430 440 450
EDALTENDRR YLQFADAFER FFINQGQQNR SIEESLQIAW ALLSMLPQGE
460 470
LKRISKDHIG KYYGQKLEEI WGAPQALD
Length:478
Mass (Da):53,160
Last modified:June 20, 2003 - v2
Checksum:i43ABBFA6931AAFF3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti75 – 751L → W in CAA45341 (PubMed:1836357).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63855 Genomic DNA. Translation: CAA45341.1.
D63799 Genomic DNA. Translation: BAA09874.2.
AP008226 Genomic DNA. Translation: BAD71095.1.
PIRiB56812.
RefSeqiWP_011173333.1. NC_006461.1.
YP_144538.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD71095; BAD71095; BAD71095.
GeneIDi3169042.
KEGGittj:TTHA1272.
PATRICi23957507. VBITheThe93045_1251.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63855 Genomic DNA. Translation: CAA45341.1.
D63799 Genomic DNA. Translation: BAA09874.2.
AP008226 Genomic DNA. Translation: BAD71095.1.
PIRiB56812.
RefSeqiWP_011173333.1. NC_006461.1.
YP_144538.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3A5CX-ray4.51D/E/F/L/M/N1-478[»]
3A5DX-ray4.80D/E/F/L/M/N1-478[»]
3GQBX-ray2.80B/D1-464[»]
3J0Jelectron microscopy9.70D/E/F1-478[»]
3W3AX-ray3.90D/E/F/L/M/N7-463[»]
5GARelectron microscopy6.40D/E/F7-463[»]
5GASelectron microscopy9.50D/E/F7-463[»]
ProteinModelPortaliQ56404.
SMRiQ56404. Positions 16-463.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ56404. 1 interaction.
MINTiMINT-7297946.
STRINGi300852.TTHA1272.

Proteomic databases

PRIDEiQ56404.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD71095; BAD71095; BAD71095.
GeneIDi3169042.
KEGGittj:TTHA1272.
PATRICi23957507. VBITheThe93045_1251.

Phylogenomic databases

eggNOGiENOG4108JIP. Bacteria.
COG1156. LUCA.
HOGENOMiHOG000165320.
KOiK02118.
OMAiWRERRYL.
PhylomeDBiQ56404.

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-1306-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ56404.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00310. ATP_synth_B_arch. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039114. V-ATPsynth_beta/V-ATPase_B. 1 hit.
SUPFAMiSSF47917. SSF47917. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVATB_THET8
AccessioniPrimary (citable) accession number: Q56404
Secondary accession number(s): Q5SIU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: June 20, 2003
Last modified: September 7, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.