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Protein

V-type ATP synthase beta chain

Gene

atpB

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type ATP synthase beta chain
Alternative name(s):
V-ATPase subunit B
Gene namesi
Name:atpB
Ordered Locus Names:TTHA1272
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001446821 – 478V-type ATP synthase beta chainAdd BLAST478

Proteomic databases

PRIDEiQ56404.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
atpAQ564032EBI-7260036,EBI-7260009

Protein-protein interaction databases

IntActiQ56404. 1 interactor.
MINTiMINT-7297946.
STRINGi300852.TTHA1272.

Structurei

Secondary structure

1478
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi11 – 15Combined sources5
Beta strandi18 – 23Combined sources6
Beta strandi32 – 36Combined sources5
Beta strandi42 – 61Combined sources20
Beta strandi68 – 70Combined sources3
Beta strandi72 – 79Combined sources8
Beta strandi81 – 84Combined sources4
Turni87 – 90Combined sources4
Beta strandi91 – 94Combined sources4
Beta strandi101 – 103Combined sources3
Beta strandi109 – 113Combined sources5
Helixi121 – 123Combined sources3
Helixi136 – 139Combined sources4
Beta strandi152 – 155Combined sources4
Helixi160 – 170Combined sources11
Helixi175 – 178Combined sources4
Beta strandi187 – 196Combined sources10
Helixi198 – 210Combined sources13
Helixi213 – 216Combined sources4
Beta strandi217 – 223Combined sources7
Helixi229 – 247Combined sources19
Beta strandi252 – 258Combined sources7
Helixi260 – 272Combined sources13
Turni273 – 275Combined sources3
Helixi280 – 282Combined sources3
Helixi287 – 295Combined sources9
Beta strandi307 – 316Combined sources10
Helixi324 – 332Combined sources9
Beta strandi333 – 339Combined sources7
Helixi341 – 345Combined sources5
Turni354 – 356Combined sources3
Helixi362 – 364Combined sources3
Turni368 – 370Combined sources3
Helixi375 – 395Combined sources21
Beta strandi397 – 399Combined sources3
Helixi407 – 410Combined sources4
Helixi413 – 420Combined sources8
Turni421 – 423Combined sources3
Helixi432 – 443Combined sources12
Helixi448 – 450Combined sources3
Helixi456 – 462Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3A5CX-ray4.51D/E/F/L/M/N1-478[»]
3A5DX-ray4.80D/E/F/L/M/N1-478[»]
3GQBX-ray2.80B/D1-464[»]
3J0Jelectron microscopy9.70D/E/F1-478[»]
3W3AX-ray3.90D/E/F/L/M/N7-463[»]
5GARelectron microscopy6.40D/E/F7-463[»]
5GASelectron microscopy9.50D/E/F7-463[»]
ProteinModelPortaliQ56404.
SMRiQ56404.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ56404.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.Curated

Phylogenomic databases

eggNOGiENOG4108JIP. Bacteria.
COG1156. LUCA.
HOGENOMiHOG000165320.
KOiK02118.
OMAiWRERRYL.
PhylomeDBiQ56404.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00310. ATP_synth_B_arch. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR004100. ATPase_F1/V1/A1_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR024034. ATPase_F1/V1_bsu_C.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039114. V-ATPsynth_beta/V-ATPase_B. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q56404-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLLKKEYTG ITYISGPLLF VENAKDLAYG AIVDIKDGTG RVRGGQVIEV
60 70 80 90 100
SEEYAVIQVF EETTGLDLAT TSVSLVEDVA RLGVSKEMLG RRFNGIGKPI
110 120 130 140 150
DGLPPITPEK RLPITGLPLN PVARRKPEQF IQTGISTIDV MNTLVRGQKL
160 170 180 190 200
PIFSGSGLPA NEIAAQIARQ ATVRPDLSGE GEKEEPFAVV FAAMGITQRE
210 220 230 240 250
LSYFIQEFER TGALSRSVLF LNKADDPTIE RILTPRMALT VAEYLAFEHD
260 270 280 290 300
YHVLVILTDM TNYCEALREI GAAREEIPGR RGYPGYMYTD LATIYERAGV
310 320 330 340 350
VEGKKGSVTQ IPILSMPDDD RTHPIPDLTG YITEGQIQLS RELHRKGIYP
360 370 380 390 400
PIDPLPSLSR LMNNGVGKGK TREDHKQVSD QLYSAYANGV DIRKLVAIIG
410 420 430 440 450
EDALTENDRR YLQFADAFER FFINQGQQNR SIEESLQIAW ALLSMLPQGE
460 470
LKRISKDHIG KYYGQKLEEI WGAPQALD
Length:478
Mass (Da):53,160
Last modified:June 20, 2003 - v2
Checksum:i43ABBFA6931AAFF3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti75L → W in CAA45341 (PubMed:1836357).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63855 Genomic DNA. Translation: CAA45341.1.
D63799 Genomic DNA. Translation: BAA09874.2.
AP008226 Genomic DNA. Translation: BAD71095.1.
PIRiB56812.
RefSeqiWP_011173333.1. NC_006461.1.
YP_144538.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD71095; BAD71095; BAD71095.
GeneIDi3169042.
KEGGittj:TTHA1272.
PATRICi23957507. VBITheThe93045_1251.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63855 Genomic DNA. Translation: CAA45341.1.
D63799 Genomic DNA. Translation: BAA09874.2.
AP008226 Genomic DNA. Translation: BAD71095.1.
PIRiB56812.
RefSeqiWP_011173333.1. NC_006461.1.
YP_144538.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3A5CX-ray4.51D/E/F/L/M/N1-478[»]
3A5DX-ray4.80D/E/F/L/M/N1-478[»]
3GQBX-ray2.80B/D1-464[»]
3J0Jelectron microscopy9.70D/E/F1-478[»]
3W3AX-ray3.90D/E/F/L/M/N7-463[»]
5GARelectron microscopy6.40D/E/F7-463[»]
5GASelectron microscopy9.50D/E/F7-463[»]
ProteinModelPortaliQ56404.
SMRiQ56404.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ56404. 1 interactor.
MINTiMINT-7297946.
STRINGi300852.TTHA1272.

Proteomic databases

PRIDEiQ56404.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD71095; BAD71095; BAD71095.
GeneIDi3169042.
KEGGittj:TTHA1272.
PATRICi23957507. VBITheThe93045_1251.

Phylogenomic databases

eggNOGiENOG4108JIP. Bacteria.
COG1156. LUCA.
HOGENOMiHOG000165320.
KOiK02118.
OMAiWRERRYL.
PhylomeDBiQ56404.

Miscellaneous databases

EvolutionaryTraceiQ56404.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00310. ATP_synth_B_arch. 1 hit.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR004100. ATPase_F1/V1/A1_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR024034. ATPase_F1/V1_bsu_C.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
PIRSFiPIRSF039114. V-ATPsynth_beta/V-ATPase_B. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVATB_THET8
AccessioniPrimary (citable) accession number: Q56404
Secondary accession number(s): Q5SIU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: June 20, 2003
Last modified: November 30, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.