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Q56328

- TPN38_TREPA

UniProt

Q56328 - TPN38_TREPA

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Protein

Membrane lipoprotein TpN38(b)

Gene

tpn38

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-321-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane lipoprotein TpN38(b)
Gene namesi
Name:tpn38
Ordered Locus Names:TP_0298
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

Subcellular locationi

Cell membrane Curated; Lipid-anchor Curated

GO - Cellular componenti

  1. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919By similarityAdd
BLAST
Chaini20 – 343324Membrane lipoprotein TpN38(b)PRO_0000018008Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi20 – 201N-palmitoyl cysteineBy similarity
Lipidationi20 – 201S-diacylglycerol cysteineBy similarity

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Protein-protein interaction databases

IntActiQ56328. 9 interactions.
STRINGi243276.TP0298.

Structurei

Secondary structure

1
343
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi30 – 389
Helixi44 – 6118
Turni62 – 643
Beta strandi67 – 737
Helixi78 – 803
Helixi81 – 9010
Beta strandi95 – 1017
Helixi104 – 11411
Beta strandi120 – 1245
Beta strandi131 – 1388
Helixi140 – 15617
Beta strandi167 – 1748
Helixi177 – 1815
Helixi183 – 19412
Beta strandi199 – 2046
Beta strandi206 – 2094
Helixi211 – 22414
Beta strandi228 – 2325
Helixi234 – 2363
Helixi237 – 24711
Beta strandi250 – 2567
Helixi259 – 2613
Turni263 – 2653
Beta strandi266 – 2727
Helixi274 – 28613
Beta strandi294 – 2985
Helixi300 – 3023
Beta strandi304 – 3074
Helixi312 – 3176
Helixi320 – 33516
Beta strandi336 – 3383

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IILX-ray1.30A21-343[»]
ProteinModelPortaliQ56328.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BMP lipoprotein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG1744.
KOiK02058.
OMAiNQREQAY.
OrthoDBiEOG6Z9B3D.

Family and domain databases

InterProiIPR003760. Bmp.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF02608. Bmp. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q56328 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNGAVCVLSA LIAVFTCFSC RPAVQDERAV RIAVFVPGFR HDSPVYAMLC
60 70 80 90 100
DGVERAVTQE RATGRSIGLD IIEAGPNQAL WREKLAHLAA EQRYRLIVSS
110 120 130 140 150
NPALPHVLEP ILRQFPLQRF LVLDAYAPQE HSLITFRYNQ WEQAYLAGHL
160 170 180 190 200
SALVSASAMR FANADKKIGL IAGQSYPVMT QTIIPAFLAG ARAVDPAFEV
210 220 230 240 250
DVRVVGNWYD AAKSADLARI LFHEGVDVMM PICGGANQGV LAAARELGFY
260 270 280 290 300
VSWFDDNGYA RAPGYVVGSS VMEQERLAYE QTLRCIRGEL PSAGAWTLGV
310 320 330 340
KDGYVRFIEE DPLYLQTVPE PIRVRQSALL RRIQSGELTL PVR
Length:343
Mass (Da):37,882
Last modified:November 1, 1996 - v1
Checksum:i800687C5A1420C4D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12861 Genomic DNA. Translation: AAB02167.1.
AE000520 Genomic DNA. Translation: AAC65287.1.
PIRiD71341.
RefSeqiNP_218739.1. NC_000919.1.
WP_010881747.1. NC_021490.2.
YP_008091158.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65287; AAC65287; TP_0298.
GeneIDi15851594.
2611215.
KEGGitpa:TP0298.
tpw:TPANIC_0298.
PATRICi20530587. VBITrePal57110_0316.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12861 Genomic DNA. Translation: AAB02167.1 .
AE000520 Genomic DNA. Translation: AAC65287.1 .
PIRi D71341.
RefSeqi NP_218739.1. NC_000919.1.
WP_010881747.1. NC_021490.2.
YP_008091158.1. NC_021490.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4IIL X-ray 1.30 A 21-343 [» ]
ProteinModelPortali Q56328.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q56328. 9 interactions.
STRINGi 243276.TP0298.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65287 ; AAC65287 ; TP_0298 .
GeneIDi 15851594.
2611215.
KEGGi tpa:TP0298.
tpw:TPANIC_0298.
PATRICi 20530587. VBITrePal57110_0316.

Phylogenomic databases

eggNOGi COG1744.
KOi K02058.
OMAi NQREQAY.
OrthoDBi EOG6Z9B3D.

Enzyme and pathway databases

BioCyci TPAL243276:GC1H-321-MONOMER.

Family and domain databases

InterProi IPR003760. Bmp.
IPR028082. Peripla_BP_I.
[Graphical view ]
Pfami PF02608. Bmp. 1 hit.
[Graphical view ]
SUPFAMi SSF53822. SSF53822. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Expression and sequence analysis of a Treponema pallidum gene, Tpn38(b), encoding an exported protein with homology to T. pallidum and Borrelia burgdorferi proteins."
    Stamm L.V., Hardham J.M., Frye J.G.
    FEMS Microbiol. Lett. 135:57-63(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Nichols.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nichols.

Entry informationi

Entry nameiTPN38_TREPA
AccessioniPrimary (citable) accession number: Q56328
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3