Membrane lipoprotein TpN38(b) precursor - Treponema pallidum (strain Nichols)

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Q56328 (TPN38_TREPA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 74. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Membrane lipoprotein TpN38(b)

Gene names

Name:	tpn38
Ordered Locus Names:	TP_0298

Organism

Treponema pallidum (strain Nichols) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema ›

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cell membrane; Lipid-anchor Probable.
Sequence similarities	Belongs to the BMP lipoprotein family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

19

By similarity

Chain

324

Membrane lipoprotein TpN38(b)

PRO_0000018008

Amino acid modifications

Lipidation

1

N-palmitoyl cysteine By similarity

Lipidation

1

S-diacylglycerol cysteine By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q56328 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 800687C5A1420C4D
Show »

343

37,882

        10         20         30         40         50         60 
MNGAVCVLSA LIAVFTCFSC RPAVQDERAV RIAVFVPGFR HDSPVYAMLC DGVERAVTQE 

        70         80         90        100        110        120 
RATGRSIGLD IIEAGPNQAL WREKLAHLAA EQRYRLIVSS NPALPHVLEP ILRQFPLQRF 

       130        140        150        160        170        180 
LVLDAYAPQE HSLITFRYNQ WEQAYLAGHL SALVSASAMR FANADKKIGL IAGQSYPVMT 

       190        200        210        220        230        240 
QTIIPAFLAG ARAVDPAFEV DVRVVGNWYD AAKSADLARI LFHEGVDVMM PICGGANQGV 

       250        260        270        280        290        300 
LAAARELGFY VSWFDDNGYA RAPGYVVGSS VMEQERLAYE QTLRCIRGEL PSAGAWTLGV 

       310        320        330        340 
KDGYVRFIEE DPLYLQTVPE PIRVRQSALL RRIQSGELTL PVR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Expression and sequence analysis of a Treponema pallidum gene, Tpn38(b), encoding an exported protein with homology to T. pallidum and Borrelia burgdorferi proteins." Stamm L.V., Hardham J.M., Frye J.G. FEMS Microbiol. Lett. 135:57-63(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Nichols.
[2]	"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. Venter J.C. Science 281:375-388(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U12861 Genomic DNA. Translation: AAB02167.1.
AE000520 Genomic DNA. Translation: AAC65287.1.

PIR

RefSeq

NP_218739.1. NC_000919.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4IIL	X-ray	1.30	A	21-343	[»]

ProteinModelPortal

ModBase

Protein-protein interaction databases

IntAct

Q56328. 9 interactions.

STRING

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

AAC65287; AAC65287; TP_0298.

GeneID

KEGG

PATRIC

20530587. VBITrePal57110_0316.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

KO

OMA

ProtClustDB

Family and domain databases

InterPro

IPR003760. Bmp.
[Graphical view]

Pfam

PF02608. Bmp. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

TPN38_TREPA

Accession

Primary (citable) accession number: Q56328

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 4, 2001
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents