Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q56328 (TPN38_TREPA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Membrane lipoprotein TpN38(b)
Gene names
Name:tpn38
Ordered Locus Names:TP_0298
OrganismTreponema pallidum (strain Nichols) [Complete proteome] [HAMAP]
Taxonomic identifier243276 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cell membrane; Lipid-anchor Probable.

Sequence similarities

Belongs to the BMP lipoprotein family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainSignal
   PTMLipoprotein
Palmitate
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 By similarity
Chain20 – 343324Membrane lipoprotein TpN38(b)
PRO_0000018008

Amino acid modifications

Lipidation201N-palmitoyl cysteine By similarity
Lipidation201S-diacylglycerol cysteine By similarity

Secondary structure

.......................................................... 343
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q56328 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 800687C5A1420C4D

FASTA34337,882
        10         20         30         40         50         60 
MNGAVCVLSA LIAVFTCFSC RPAVQDERAV RIAVFVPGFR HDSPVYAMLC DGVERAVTQE 

        70         80         90        100        110        120 
RATGRSIGLD IIEAGPNQAL WREKLAHLAA EQRYRLIVSS NPALPHVLEP ILRQFPLQRF 

       130        140        150        160        170        180 
LVLDAYAPQE HSLITFRYNQ WEQAYLAGHL SALVSASAMR FANADKKIGL IAGQSYPVMT 

       190        200        210        220        230        240 
QTIIPAFLAG ARAVDPAFEV DVRVVGNWYD AAKSADLARI LFHEGVDVMM PICGGANQGV 

       250        260        270        280        290        300 
LAAARELGFY VSWFDDNGYA RAPGYVVGSS VMEQERLAYE QTLRCIRGEL PSAGAWTLGV 

       310        320        330        340 
KDGYVRFIEE DPLYLQTVPE PIRVRQSALL RRIQSGELTL PVR 

« Hide

References

« Hide 'large scale' references
[1]"Expression and sequence analysis of a Treponema pallidum gene, Tpn38(b), encoding an exported protein with homology to T. pallidum and Borrelia burgdorferi proteins."
Stamm L.V., Hardham J.M., Frye J.G.
FEMS Microbiol. Lett. 135:57-63(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Nichols.
[2]"Complete genome sequence of Treponema pallidum, the syphilis spirochete."
Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. expand/collapse author list , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C.
Science 281:375-388(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nichols.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U12861 Genomic DNA. Translation: AAB02167.1.
AE000520 Genomic DNA. Translation: AAC65287.1.
PIRD71341.
RefSeqNP_218739.1. NC_000919.1.
YP_008091158.1. NC_021490.2.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4IILX-ray1.30A21-343[»]
ProteinModelPortalQ56328.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ56328. 9 interactions.
STRING243276.TP0298.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC65287; AAC65287; TP_0298.
GeneID15851594.
2611215.
KEGGtpa:TP0298.
tpw:TPANIC_0298.
PATRIC20530587. VBITrePal57110_0316.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1744.
KOK02058.
OMANQREQAY.
OrthoDBEOG6Z9B3D.

Enzyme and pathway databases

BioCycTPAL243276:GC1H-321-MONOMER.

Family and domain databases

InterProIPR003760. Bmp.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamPF02608. Bmp. 1 hit.
[Graphical view]
SUPFAMSSF53822. SSF53822. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTPN38_TREPA
AccessionPrimary (citable) accession number: Q56328
Entry history
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references