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Q56312 (CHEY_THEMA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chemotaxis protein CheY
Gene names
Name:cheY
Ordered Locus Names:TM_0700
OrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP]
Taxonomic identifier243274 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length120 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation By similarity.

Cofactor

Binds 1 magnesium ion per subunit.

Subcellular location

Cytoplasm.

Post-translational modification

Phosphorylated by CheA By similarity.

Sequence similarities

Contains 1 response regulatory domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 120120Chemotaxis protein CheY
PRO_0000081055

Regions

Domain1 – 119119Response regulatory

Sites

Metal binding91Magnesium
Metal binding101Magnesium
Metal binding541Magnesium
Metal binding561Magnesium; via carbonyl oxygen

Amino acid modifications

Modified residue5414-aspartylphosphate

Secondary structure

...................... 120
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q56312 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 195AC95641264E63

FASTA12013,217
        10         20         30         40         50         60 
MGKRVLIVDD AAFMRMMLKD IITKAGYEVA GEATNGREAV EKYKELKPDI VTMDITMPEM 

        70         80         90        100        110        120 
NGIDAIKEIM KIDPNAKIIV CSAMGQQAMV IEAIKAGAKD FIVKPFQPSR VVEALNKVSK 

« Hide

References

« Hide 'large scale' references
[1]"Thermostable chemotaxis proteins from the hyperthermophilic bacterium Thermotoga maritima."
Swanson R.V., Sanna M.G., Simon M.I.
J. Bacteriol. 178:484-489(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
[2]"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. expand/collapse author list , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[3]"Crystal structures of CheY from Thermotoga maritima do not support conventional explanations for the structural basis of enhanced thermostability."
Usher K.C., de la Cruz A.F.A., Dahlquist F.W., Swanson R.V., Simon M.I., Remington S.J.
Protein Sci. 7:403-412(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U30501 Genomic DNA. Translation: AAA96389.1.
AE000512 Genomic DNA. Translation: AAD35782.1.
PIRB72346.
RefSeqNP_228509.1. NC_000853.1.
YP_007977050.1. NC_021214.1.
YP_008990331.1. NC_023151.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1TMYX-ray1.90A1-120[»]
1U0SX-ray1.90Y2-119[»]
2LLENMR-A1-103[»]
2TMYX-ray2.30A1-120[»]
3TMYX-ray2.20A/B1-120[»]
4IGAX-ray1.73A1-120[»]
4TMYX-ray2.80A/B1-120[»]
ProteinModelPortalQ56312.
SMRQ56312. Positions 2-119.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ56312. 1 interaction.
STRING243274.TM0700.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD35782; AAD35782; TM_0700.
GeneID15494303.
18092089.
898367.
KEGGtma:TM0700.
tmm:Tmari_0700.
PATRIC23936318. VBITheMar51294_0712.

Phylogenomic databases

eggNOGCOG0784.
KOK03413.
OMAMRMMIKN.
OrthoDBEOG6PKFC7.
ProtClustDBCLSK875308.

Family and domain databases

InterProIPR011006. CheY-like_superfamily.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamPF00072. Response_reg. 1 hit.
[Graphical view]
SMARTSM00448. REC. 1 hit.
[Graphical view]
SUPFAMSSF52172. SSF52172. 1 hit.
PROSITEPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ56312.

Entry information

Entry nameCHEY_THEMA
AccessionPrimary (citable) accession number: Q56312
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references