Q56265 (Q56265_THEFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Endo-1,4-beta-xylanase RuleBase RU004392 EC=3.2.1.8 RuleBase RU004392
Organism	Thermomonospora fusca EMBL AAA21480.1
Taxonomic identifier	2021 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family. RuleBase RU003433

Ontologies

Keywords
Biological process	Xylan degradation RuleBase RU004392 RuleBase RU003433 EMBL AAA21480.1
Domain	Signal EMBL AAA21480.1
Molecular function	Glycosidase RuleBase RU004392 RuleBase RU003433 Hydrolase
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC polysaccharide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 42	42	Potential EMBL AAA21480.1
	Chain	43 – 338	296	endo 1,4-beta-D xylanase EMBL AAA21480.1		PRO_5000143928

Sequences

	Sequence		Length	Mass (Da)
	Q56265 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 188AF3AA8430A3C7	FASTA	338	36,406
	10 20 30 40 50 60 MNHAPASLKS RRRFRPRLLI GKAFAAALVA VVTMIPSTAA HAAVTSNETG YHDGYFYSFW 70 80 90 100 110 120 TDAPGTVSME LGPGGNYSTS WRNTGNFVAG KGWATGGRRT VTYSASFNPS GNAYLTLYGW 130 140 150 160 170 180 TRNPLVEYYI VESWGTYRPT GTYMGTVTTD GGTYDIYKTT RYNAPSIEGT RTFDQYWSVR 190 200 210 220 230 240 QSKRTSGTIT AGNHFDAWAR HGMHLGTHDY MIMATEGYQS SGSSNVTLGT SGGGNPGGGN 250 260 270 280 290 300 PPGGGNPPGG GGCTATLSAG QQWNDRYNLN VNVSGSNNWT VTVNVPWPAR IIATWNIHAS 310 320 330 YPDSQTLVAR PNGNGNNWGM TIMHNGNWTW PTVSCSAN

References

[1]	"Cloning of a Thermomonospora fusca xylanase gene and its expression in Escherichia coli and Streptomyces lividans." Ghangas G.S., Hu Y.J., Wilson D.B. J. Bacteriol. 171:2963-2969(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YX EMBL AAA21480.1.
[2]	"Characterization and sequence of a Thermomonospora fusca xylanase." Irwin D., Jung E.D., Wilson D.B. Appl. Environ. Microbiol. 60:763-770(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YX EMBL AAA21480.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U01242 Genomic DNA. Translation: AAA21480.1.
RefSeq	YP_289274.1. NC_007333.1.
3D structure databases
HSSP	HSSP built from PDB template 1M4W based on UniProtKB Q8GMV7.
ProteinModelPortal	Q56265.
SMR	Q56265. Positions 44-272.
ModBase	Search...
Protein family/group databases
CAZy	CBM2. Carbohydrate-Binding Module Family 2. GH11. Glycoside Hydrolase Family 11.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3580704.
KEGG	tfu:Tfu_1213.
Phylogenomic databases
KO	K01181.
Enzyme and pathway databases
UniPathway	UPA00114.
Family and domain databases
Gene3D	2.60.120.180. 1 hit. 2.60.40.290. 1 hit.
InterPro	IPR008965. Carb-bd_dom. IPR012291. CBD_carb-bd_dom. IPR001919. Cellulose-bd_dom_fam2_bac. IPR008985. ConA-like_lec_gl_sf. IPR001137. Glyco_hydro_11. IPR013319. Glyco_hydro_11/12. IPR018208. Glyco_hydro_11_AS. [Graphical view]
Pfam	PF00457. Glyco_hydro_11. 1 hit. [Graphical view]
PRINTS	PR00911. GLHYDRLASE11.
SMART	SM00637. CBD_II. 1 hit. [Graphical view]
SUPFAM	SSF49384. Cellul_bind. 1 hit. SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS51173. CBM2. 1 hit. PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit. PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q56265_THEFU

Accession

Primary (citable) accession number: Q56265

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)