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Q56254

- RPOM_THECE

UniProt

Q56254 - RPOM_THECE

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Protein
DNA-directed RNA polymerase subunit M
Gene
rpoM
Organism
Thermococcus celer
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri4 – 2522C4-type Reviewed prediction
Add
BLAST
Zinc fingeri67 – 10741TFIIS-type
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit M (EC:2.7.7.6)
Gene namesi
Name:rpoM
OrganismiThermococcus celer
Taxonomic identifieri2264 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 110110DNA-directed RNA polymerase subunit M
PRO_0000121483Add
BLAST

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi62 – 643
Beta strandi66 – 683
Turni72 – 743
Beta strandi77 – 848
Beta strandi87 – 904
Beta strandi92 – 10211
Beta strandi105 – 1073

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QYPNMR-A58-110[»]
ProteinModelPortaliQ56254.
SMRiQ56254. Positions 57-110.

Miscellaneous databases

EvolutionaryTraceiQ56254.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Zinc-finger

Family and domain databases

InterProiIPR019761. DNA-dir_RNA_pol-M_15_CS.
IPR001529. DNA-dir_RNA_pol_M/15kDasu.
IPR012164. DNA-dir_RNApol_C11.
IPR006288. TFS/rpoM.
IPR001222. Znf_TFIIS.
[Graphical view]
PfamiPF02150. RNA_POL_M_15KD. 1 hit.
PF01096. TFIIS_C. 1 hit.
[Graphical view]
PIRSFiPIRSF005586. RNApol_RpoM. 1 hit.
SMARTiSM00661. RPOL9. 1 hit.
SM00440. ZnF_C2C2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01384. TFS_arch. 1 hit.
PROSITEiPS01030. RNA_POL_M_15KD. 1 hit.
PS00466. ZF_TFIIS_1. 1 hit.
PS51133. ZF_TFIIS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q56254-1 [UniParc]FASTAAdd to Basket

« Hide

MKFCPKCGNL MLPDRKRKVW VCRSCGYEEP FDEEKDREKT VIKQEVKHKP    50
DEGIVVIEQD LKTLPTTKIT CPKCGNDTAY WWEMQTRAGD EPSTIFYKCT 100
KCGHTWRSYE 110
Length:110
Mass (Da):12,970
Last modified:November 1, 1996 - v1
Checksum:i3AE99D6905FD4E4E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L27650 Unassigned DNA. Translation: AAA72052.1.
PIRiA55263.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L27650 Unassigned DNA. Translation: AAA72052.1 .
PIRi A55263.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1QYP NMR - A 58-110 [» ]
ProteinModelPortali Q56254.
SMRi Q56254. Positions 57-110.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q56254.

Family and domain databases

InterProi IPR019761. DNA-dir_RNA_pol-M_15_CS.
IPR001529. DNA-dir_RNA_pol_M/15kDasu.
IPR012164. DNA-dir_RNApol_C11.
IPR006288. TFS/rpoM.
IPR001222. Znf_TFIIS.
[Graphical view ]
Pfami PF02150. RNA_POL_M_15KD. 1 hit.
PF01096. TFIIS_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF005586. RNApol_RpoM. 1 hit.
SMARTi SM00661. RPOL9. 1 hit.
SM00440. ZnF_C2C2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01384. TFS_arch. 1 hit.
PROSITEi PS01030. RNA_POL_M_15KD. 1 hit.
PS00466. ZF_TFIIS_1. 1 hit.
PS51133. ZF_TFIIS_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The sequence, and its evolutionary implications, of a Thermococcus celer protein associated with transcription."
    Kaine B.P., Mehr I.J., Woese C.R.
    Proc. Natl. Acad. Sci. U.S.A. 91:3854-3856(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "High-resolution structure of an archaeal zinc ribbon defines a general architectural motif in eukaryotic RNA polymerases."
    Wang B., Jones D.N.M., Kaine B.P., Weiss M.A.
    Structure 6:555-569(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 54-110.

Entry informationi

Entry nameiRPOM_THECE
AccessioniPrimary (citable) accession number: Q56254
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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