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Q56254 (RPOM_THECE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit M

EC=2.7.7.6
Gene names
Name:rpoM
OrganismThermococcus celer
Taxonomic identifier2264 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length110 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Sequence similarities

Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

Contains 1 TFIIS-type zinc finger.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 110110DNA-directed RNA polymerase subunit M
PRO_0000121483

Regions

Zinc finger4 – 2522C4-type Potential
Zinc finger67 – 10741TFIIS-type

Secondary structure

............... 110
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q56254 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 3AE99D6905FD4E4E

FASTA11012,970
        10         20         30         40         50         60 
MKFCPKCGNL MLPDRKRKVW VCRSCGYEEP FDEEKDREKT VIKQEVKHKP DEGIVVIEQD 

        70         80         90        100        110 
LKTLPTTKIT CPKCGNDTAY WWEMQTRAGD EPSTIFYKCT KCGHTWRSYE 

« Hide

References

[1]"The sequence, and its evolutionary implications, of a Thermococcus celer protein associated with transcription."
Kaine B.P., Mehr I.J., Woese C.R.
Proc. Natl. Acad. Sci. U.S.A. 91:3854-3856(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"High-resolution structure of an archaeal zinc ribbon defines a general architectural motif in eukaryotic RNA polymerases."
Wang B., Jones D.N.M., Kaine B.P., Weiss M.A.
Structure 6:555-569(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR OF 54-110.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L27650 Unassigned DNA. Translation: AAA72052.1.
PIRA55263.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1QYPNMR-A58-110[»]
ProteinModelPortalQ56254.
SMRQ56254. Positions 57-110.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR019761. DNA-dir_RNA_pol-M_15_CS.
IPR001529. DNA-dir_RNA_pol_M/15kDasu.
IPR012164. DNA-dir_RNApol_C11.
IPR006288. TFS/rpoM.
IPR001222. Znf_TFIIS.
[Graphical view]
PfamPF02150. RNA_POL_M_15KD. 1 hit.
PF01096. TFIIS_C. 1 hit.
[Graphical view]
PIRSFPIRSF005586. RNApol_RpoM. 1 hit.
SMARTSM00661. RPOL9. 1 hit.
SM00440. ZnF_C2C2. 1 hit.
[Graphical view]
TIGRFAMsTIGR01384. TFS_arch. 1 hit.
PROSITEPS01030. RNA_POL_M_15KD. 1 hit.
PS00466. ZF_TFIIS_1. 1 hit.
PS51133. ZF_TFIIS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ56254.

Entry information

Entry nameRPOM_THECE
AccessionPrimary (citable) accession number: Q56254
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references