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Q56206

- GLMS_SPHYA

UniProt

Q56206 - GLMS_SPHYA

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Sphingobium yanoikuyae (Sphingomonas yanoikuyae)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.By similarity

    Catalytic activityi

    L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei151 – 1511For Fru-6P isomerization activityBy similarity

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate biosynthetic process Source: InterPro
    2. glutamine metabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Aminotransferase, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
    Alternative name(s):
    D-fructose-6-phosphate amidotransferase
    GFAT
    Glucosamine-6-phosphate synthase
    Hexosephosphate aminotransferase
    L-glutamine--D-fructose-6-phosphate amidotransferase
    Gene namesi
    Name:glmS
    OrganismiSphingobium yanoikuyae (Sphingomonas yanoikuyae)
    Taxonomic identifieri13690 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingobium

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 156›156Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135378Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ56206.
    SMRiQ56206. Positions 1-156.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 146143SISPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 SIS domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Glutamine amidotransferase

    Family and domain databases

    InterProiIPR005855. GlmS_trans.
    IPR001347. SIS.
    [Graphical view]
    PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
    PfamiPF01380. SIS. 1 hit.
    [Graphical view]
    PROSITEiPS51464. SIS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q56206-1 [UniParc]FASTAAdd to Basket

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    IEAMAHHIVP ARDVLYLGRG TDYPLALEGA LKLKEISYIH AEGYAAGEMK    50
    HGPIALIDEL VPVICIAPSG PLFEKTVSNM QEVQARGGKV VLISAYDGVQ 100
    AAGEGCLATI TMPKVHPLIA PMVYAVPVQL LAYHVAVLKG TDVDQPRNLA 150
    KSVTVE 156
    Length:156
    Mass (Da):16,606
    Last modified:November 1, 1996 - v1
    Checksum:i5D661DE8EEFD4EDD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U37523 Genomic DNA. Translation: AAC43642.1.
    PIRiPC4141.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U37523 Genomic DNA. Translation: AAC43642.1 .
    PIRi PC4141.

    3D structure databases

    ProteinModelPortali Q56206.
    SMRi Q56206. Positions 1-156.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR005855. GlmS_trans.
    IPR001347. SIS.
    [Graphical view ]
    PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
    Pfami PF01380. SIS. 1 hit.
    [Graphical view ]
    PROSITEi PS51464. SIS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and expression of an isocitrate dehydrogenase-encoding gene from a polycyclic aromatic hydrocarbon oxidizer, Sphingomonas yanoikuyae B1."
      Wang Y., Lau P.C.K.
      Gene 168:15-21(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: DSM 6900 / JCM 10274 / B1.

    Entry informationi

    Entry nameiGLMS_SPHYA
    AccessioniPrimary (citable) accession number: Q56206
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3