Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

POU domain, class 3, transcription factor 1-B

Gene

pou3f1-b

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in neuronal differentiation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi286 – 345HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processNeurogenesis, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain, class 3, transcription factor 1-B
Alternative name(s):
Homeotic protein NRL-341 Publication
Short name:
XlNRL-34
Homeotic protein NRL-34-A
Gene namesi
Name:pou3f1-b
Synonyms:nrl-341 Publication, nrl34-a
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-866479 pou3f1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003896141 – 375POU domain, class 3, transcription factor 1-BAdd BLAST375

Structurei

3D structure databases

ProteinModelPortaliQ561L5
SMRiQ561L5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini194 – 268POU-specificPROSITE-ProRule annotationAdd BLAST75

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi100 – 191His-richSequence analysisAdd BLAST92

Sequence similaritiesi

Belongs to the POU transcription factor family. Class-3 subfamily.Sequence analysis

Keywords - Domaini

Homeobox

Phylogenomic databases

HOVERGENiHBG053120
KOiK09365

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
IPR013847 POU
IPR000327 POU_dom
IPR016362 TF_POU_3
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00157 Pou, 1 hit
PIRSFiPIRSF002629 Transcription_factor_POU, 1 hit
PRINTSiPR00028 POUDOMAIN
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00352 POU, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00035 POU_1, 1 hit
PS00465 POU_2, 1 hit
PS51179 POU_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q561L5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATAQYLPR NNSLPSNPLM HPDSDRMHQG TTYREVQKMM HQEYLQGLAT
60 70 80 90 100
NAGHPMSLTH HQWLPNPTSD WGSGSHLGAQ AEHGKSGVQS SREDLSSSFH
110 120 130 140 150
HHRSHLVHQQ TPSSHAWAQS GGHHLPSMSP GSNSHQPLIY SQSSYTNLNG
160 170 180 190 200
MLGPQASSLH HSMRDPLHDD PGVHDTHVES PPQHLGHHQD HSDEDAPSSD
210 220 230 240 250
DLEQFAKQFK QRRIKLGFTQ ADVGLALGTL YGNVFSQTTI CRFEALQLSF
260 270 280 290 300
KNMCKLKPLL NKWLEETDST TGSPTNLDKI AAQGRKRKKR TSIEVGVKGA
310 320 330 340 350
LENHFLKCPK PSAHEITSLA DSLQLEKEVV RVWFCNRRQK EKRMTPAGVP
360 370
HPPMEDVYSQ AETPPLHHTL QTSVQ
Length:375
Mass (Da):41,860
Last modified:May 10, 2005 - v1
Checksum:i33DB834E1D5C1257
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC093556 mRNA Translation: AAH93556.1
X54684 mRNA Translation: CAA38498.1
RefSeqiNP_001096655.1, NM_001103185.1
UniGeneiXl.21449

Genome annotation databases

GeneIDi378582
KEGGixla:378582

Similar proteinsi

Entry informationi

Entry nameiP3F1B_XENLA
AccessioniPrimary (citable) accession number: Q561L5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2009
Last sequence update: May 10, 2005
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program