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Protein

Regulatory protein SoxS

Gene

soxS

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN7CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi24 – 4320H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSENT99287:GCTI-4296-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Regulatory protein SoxS
Gene namesi
Name:soxS
Ordered Locus Names:STM4265
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 107106Regulatory protein SoxSPRO_0000194586Add
BLAST

Proteomic databases

PaxDbiQ56143.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM4265.

Structurei

3D structure databases

ProteinModelPortaliQ56143.
SMRiQ56143. Positions 5-106.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108W3Q. Bacteria.
ENOG4111IXA. LUCA.
HOGENOMiHOG000120762.
KOiK13631.
OMAiLTHWIDQ.
OrthoDBiEOG62C9DF.
PhylomeDBiQ56143.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q56143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHQQIIQTL IEWIDEHIDQ PLNIDVVAKK SGYSKWYLQR MFRTVTHQTL
60 70 80 90 100
GEYIRQRRLL LAAVELRTTE RPIFDIAMDL GYVSQQTFSR VFRREFDRTP

SDYRHRL
Length:107
Mass (Da):12,970
Last modified:January 23, 2007 - v2
Checksum:iD6EB766056356662
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U61147 Genomic DNA. Translation: AAB03868.1.
AE006468 Genomic DNA. Translation: AAL23089.1.
RefSeqiNP_463130.1. NC_003197.1.
WP_000019483.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL23089; AAL23089; STM4265.
GeneIDi1255791.
KEGGistm:STM4265.
PATRICi32387437. VBISalEnt20916_4486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U61147 Genomic DNA. Translation: AAB03868.1.
AE006468 Genomic DNA. Translation: AAL23089.1.
RefSeqiNP_463130.1. NC_003197.1.
WP_000019483.1. NC_003197.1.

3D structure databases

ProteinModelPortaliQ56143.
SMRiQ56143. Positions 5-106.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM4265.

Proteomic databases

PaxDbiQ56143.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL23089; AAL23089; STM4265.
GeneIDi1255791.
KEGGistm:STM4265.
PATRICi32387437. VBISalEnt20916_4486.

Phylogenomic databases

eggNOGiENOG4108W3Q. Bacteria.
ENOG4111IXA. LUCA.
HOGENOMiHOG000120762.
KOiK13631.
OMAiLTHWIDQ.
OrthoDBiEOG62C9DF.
PhylomeDBiQ56143.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-4296-MONOMER.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Martins E.A.L., Demple B.
    Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LT2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiSOXS_SALTY
AccessioniPrimary (citable) accession number: Q56143
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: February 17, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.