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Protein

Periplasmic beta-glucosidase

Gene

bglX

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei287 – 2871By similarity

GO - Molecular functioni

  1. beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2180-MONOMER.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Names & Taxonomyi

Protein namesi
Recommended name:
Periplasmic beta-glucosidase (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
T-cell inhibitor
Gene namesi
Name:bglX
Ordered Locus Names:STM2166
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 765745Periplasmic beta-glucosidasePRO_0000011782Add
BLAST

Proteomic databases

PaxDbiQ56078.
PRIDEiQ56078.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM2166.

Structurei

3D structure databases

ProteinModelPortaliQ56078.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG1472.
HOGENOMiHOG000031217.
KOiK05349.
OMAiLPPYKAS.
OrthoDBiEOG6DNT6C.
PhylomeDBiQ56078.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q56078-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWLCSVGVA VSLAMQPALA ENLFGNHPLT PEARDAFVTD LLKKMTVDEK
60 70 80 90 100
IGQLRLISVG PDNPKEAIRE MIKDGQVGAI FNTVTRQDIR QMQDQVMALS
110 120 130 140 150
RLKIPLFFAY DVVHGQRTVF PISLGLASSF NLDAVRTVGR VSAYEAADDG
160 170 180 190 200
LNMTWAPMVD VSRDPRWGRA SEGFGEDTYL TSIMGETMVK AMQGKSPADR
210 220 230 240 250
YSVMTSVKHF AAYGAVEGGK EYNTVDMSSQ RLFNDYMPPY KAGLDAGSGA
260 270 280 290 300
VMVALNSLNG TPATSDSWLL KDVLRDEWGF KGITVSDHGA IKELIKHGTA
310 320 330 340 350
ADPEDAVRVA LKAGVDMSMA DEYYSKYLPG LIKSGKVTMA ELDDATRHVL
360 370 380 390 400
NVKYDMGLFN DPYSHLGPKE SDPVDTNAES RLHRKEAREV ARESVVLLKN
410 420 430 440 450
RLETLPLKKS GTIAVVGPLA DSQRDVMGSW SAAGVANQSV TVLAGIQNAV
460 470 480 490 500
GDGAKILYAK GANITNDKGI VDFLNLYEEA VKIDPRSPQA MIDEAVQAAK
510 520 530 540 550
QADVVVAVVG ESQGMAHEAS SRTNITIPQS QRDLITALKA TGKPLVLVLM
560 570 580 590 600
NGRPLALVKE DQQADAILET WFAGTEGGNA IADVLFGDYN PSGKLPISFP
610 620 630 640 650
RSVGQIPVYY SHLNTGRPYN PEKPNKYTSR YFDEANGPLY PFGYGLSYTT
660 670 680 690 700
FTVSDVTLSS PTMQRDGKVT ASVEVTNTGK REGATVIQMY LQDVTASMSR
710 720 730 740 750
PVKQLKGFEK ITLKPGERKT VSFPIDIEAL KFWNQQMKYD AEPGKFNVFI
760
GVDSARVKQG SFELL
Length:765
Mass (Da):83,392
Last modified:January 23, 2002 - v2
Checksum:iC7C767E6CAC96786
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti630 – 6301R → L in BAA13102 (Ref. 1) Curated
Sequence conflicti634 – 6352EA → KP in BAA13102 (Ref. 1) Curated
Sequence conflicti656 – 6561V → F in BAA13102 (Ref. 1) Curated
Sequence conflicti674 – 6741E → K in BAA13102 (Ref. 1) Curated
Sequence conflicti717 – 7171E → K in BAA13102 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D86507 Genomic DNA. Translation: BAA13102.1.
AE006468 Genomic DNA. Translation: AAL21070.1.
RefSeqiNP_461111.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL21070; AAL21070; STM2166.
GeneIDi1253688.
KEGGistm:STM2166.
PATRICi32382923. VBISalEnt20916_2292.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D86507 Genomic DNA. Translation: BAA13102.1.
AE006468 Genomic DNA. Translation: AAL21070.1.
RefSeqiNP_461111.1. NC_003197.1.

3D structure databases

ProteinModelPortaliQ56078.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM2166.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Proteomic databases

PaxDbiQ56078.
PRIDEiQ56078.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL21070; AAL21070; STM2166.
GeneIDi1253688.
KEGGistm:STM2166.
PATRICi32382923. VBISalEnt20916_2292.

Phylogenomic databases

eggNOGiCOG1472.
HOGENOMiHOG000031217.
KOiK05349.
OMAiLPPYKAS.
OrthoDBiEOG6DNT6C.
PhylomeDBiQ56078.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2180-MONOMER.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Matsui K.
    Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LT2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiBGLX_SALTY
AccessioniPrimary (citable) accession number: Q56078
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2002
Last modified: January 7, 2015
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.