Q56078 (BGLX_SALTY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Periplasmic beta-glucosidase
EC=3.2.1.21

Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
T-cell inhibitor

Gene names

Name:	bglX
Ordered Locus Names:	STM2166

Organism

Salmonella typhimurium

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	765 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.
Subcellular location	Periplasm.
Sequence similarities	Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	beta-glucosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 765	745	Periplasmic beta-glucosidase		PRO_0000011782
Sites
	Active site	287	1	By similarity
Experimental info
	Sequence conflict	630	1	R → L in BAA13102. Ref.1
	Sequence conflict	634 – 635	2	EA → KP in BAA13102. Ref.1
	Sequence conflict	656	1	V → F in BAA13102. Ref.1
	Sequence conflict	674	1	E → K in BAA13102. Ref.1
	Sequence conflict	717	1	E → K in BAA13102. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q56078 [UniParc]. Last modified January 23, 2002. Version 2. Checksum: C7C767E6CAC96786	FASTA	765	83,392
	10 20 30 40 50 60 MKWLCSVGVA VSLAMQPALA ENLFGNHPLT PEARDAFVTD LLKKMTVDEK IGQLRLISVG 70 80 90 100 110 120 PDNPKEAIRE MIKDGQVGAI FNTVTRQDIR QMQDQVMALS RLKIPLFFAY DVVHGQRTVF 130 140 150 160 170 180 PISLGLASSF NLDAVRTVGR VSAYEAADDG LNMTWAPMVD VSRDPRWGRA SEGFGEDTYL 190 200 210 220 230 240 TSIMGETMVK AMQGKSPADR YSVMTSVKHF AAYGAVEGGK EYNTVDMSSQ RLFNDYMPPY 250 260 270 280 290 300 KAGLDAGSGA VMVALNSLNG TPATSDSWLL KDVLRDEWGF KGITVSDHGA IKELIKHGTA 310 320 330 340 350 360 ADPEDAVRVA LKAGVDMSMA DEYYSKYLPG LIKSGKVTMA ELDDATRHVL NVKYDMGLFN 370 380 390 400 410 420 DPYSHLGPKE SDPVDTNAES RLHRKEAREV ARESVVLLKN RLETLPLKKS GTIAVVGPLA 430 440 450 460 470 480 DSQRDVMGSW SAAGVANQSV TVLAGIQNAV GDGAKILYAK GANITNDKGI VDFLNLYEEA 490 500 510 520 530 540 VKIDPRSPQA MIDEAVQAAK QADVVVAVVG ESQGMAHEAS SRTNITIPQS QRDLITALKA 550 560 570 580 590 600 TGKPLVLVLM NGRPLALVKE DQQADAILET WFAGTEGGNA IADVLFGDYN PSGKLPISFP 610 620 630 640 650 660 RSVGQIPVYY SHLNTGRPYN PEKPNKYTSR YFDEANGPLY PFGYGLSYTT FTVSDVTLSS 670 680 690 700 710 720 PTMQRDGKVT ASVEVTNTGK REGATVIQMY LQDVTASMSR PVKQLKGFEK ITLKPGERKT 730 740 750 760 VSFPIDIEAL KFWNQQMKYD AEPGKFNVFI GVDSARVKQG SFELL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Matsui K. Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: LT2.
[2]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D86507 Genomic DNA. Translation: BAA13102.1. AE006468 Genomic DNA. Translation: AAL21070.1.
RefSeq	NP_461111.1. NC_003197.1.
3D structure databases
ProteinModelPortal	Q56078.
ModBase	Search...
Protein family/group databases
CAZy	GH3. Glycoside Hydrolase Family 3.
Proteomic databases
PRIDE	Q56078.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1253688.
GenomeReviews	Gene locus STM2166 in contig AE006468_GR.
KEGG	stm:STM2166.
NMPDR	fig|99287.1.peg.2092.
PATRIC	32382923. VBISalEnt20916_2292.
Phylogenomic databases
HOGENOM	HBG749096.
OMA	RTNITIP.
ProtClustDB	PRK15098.
Enzyme and pathway databases
BioCyc	STYP99287:STM2166-MONOMER.
Family and domain databases
InterPro	IPR019800. Glyco_hydro_3_AS. IPR002772. Glyco_hydro_3_C. IPR001764. Glyco_hydro_3_N. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.40.50.1700. G3DSA:3.40.50.1700. 1 hit. G3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
KO	K05349.
Pfam	PF00933. Glyco_hydro_3. 1 hit. PF01915. Glyco_hydro_3_C. 1 hit. [Graphical view]
PRINTS	PR00133. GLHYDRLASE3.
SUPFAM	SSF52279. Glyco_hydro_3_C. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BGLX_SALTY

Accession

Primary (citable) accession number: Q56078

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	January 23, 2002
Last modified:	January 25, 2012
This is version 78 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program