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Protein

Surface presentation of antigens protein SpaP

Gene

spaP

Organism
Salmonella typhi
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
Surface presentation of antigens protein SpaP
Gene namesi
Name:spaP
Ordered Locus Names:STY3013, t2792
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002670 Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Transmembranei55 – 75HelicalSequence analysisAdd BLAST21
Transmembranei161 – 181HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001919911 – 224Surface presentation of antigens protein SpaPAdd BLAST224

Interactioni

Protein-protein interaction databases

STRINGi220341.STY3013.

Family & Domainsi

Sequence similaritiesi

Belongs to the FliP/MopC/SpaP family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41075IY. Bacteria.
COG4790. LUCA.
HOGENOMiHOG000253557.
KOiK03226.
OMAiREYLVHY.

Family and domain databases

InterProiIPR005838. T3SS_IM_P.
IPR005773. YopR.
[Graphical view]
PfamiPF00813. FliP. 1 hit.
[Graphical view]
PRINTSiPR01302. TYPE3IMPPROT.
TIGRFAMsiTIGR01102. yscR. 1 hit.
PROSITEiPS01060. FLIP_1. 1 hit.
PS01061. FLIP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q56023-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNDISLIAL LAFSTLLPFI IASGTCFVKF SIVFVMVRNA LGLQQIPSNM
60 70 80 90 100
TLNSVALLLS MFVMWPIMHD AYVYFEDEDV TFNDISSLSK HVDEGLDGYR
110 120 130 140 150
DYLIKYSDRE LVQFFENAQL KRQYGEETET VKRDKDEIEK PSIFALLPAY
160 170 180 190 200
ALSEIKSAFK IGFYLYLPFV VVDLVVSSVL LALGMMMMSP VTISTPIKLV
210 220
LFVALDGWTL LSKGLILQYM DIAT
Length:224
Mass (Da):25,262
Last modified:November 1, 1997 - v1
Checksum:i0352C1D88DAECA24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29363 Genomic DNA. Translation: AAC43861.1.
AL513382 Genomic DNA. Translation: CAD05997.1.
AE014613 Genomic DNA. Translation: AAO70353.1.
RefSeqiNP_457284.1. NC_003198.1.
WP_000526019.1. NZ_LUHL01000002.1.

Genome annotation databases

EnsemblBacteriaiAAO70353; AAO70353; t2792.
CAD05997; CAD05997; CAD05997.
GeneIDi1249319.
KEGGistt:t2792.
sty:STY3013.
PATRICi18544074. VBISalEnt120419_3067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29363 Genomic DNA. Translation: AAC43861.1.
AL513382 Genomic DNA. Translation: CAD05997.1.
AE014613 Genomic DNA. Translation: AAO70353.1.
RefSeqiNP_457284.1. NC_003198.1.
WP_000526019.1. NZ_LUHL01000002.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220341.STY3013.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO70353; AAO70353; t2792.
CAD05997; CAD05997; CAD05997.
GeneIDi1249319.
KEGGistt:t2792.
sty:STY3013.
PATRICi18544074. VBISalEnt120419_3067.

Phylogenomic databases

eggNOGiENOG41075IY. Bacteria.
COG4790. LUCA.
HOGENOMiHOG000253557.
KOiK03226.
OMAiREYLVHY.

Family and domain databases

InterProiIPR005838. T3SS_IM_P.
IPR005773. YopR.
[Graphical view]
PfamiPF00813. FliP. 1 hit.
[Graphical view]
PRINTSiPR01302. TYPE3IMPPROT.
TIGRFAMsiTIGR01102. yscR. 1 hit.
PROSITEiPS01060. FLIP_1. 1 hit.
PS01061. FLIP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPAP_SALTI
AccessioniPrimary (citable) accession number: Q56023
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.