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Q55GW2 (PPAC_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Low molecular weight phosphotyrosine protein phosphatase

Short name=LMW-PTP
Short name=LMW-PTPase
EC=3.1.3.48
Alternative name(s):
Low molecular weight cytosolic acid phosphatase
EC=3.1.3.2
Gene names
Name:acp1
ORF Names:DDB_G0267484
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

A phosphate monoester + H2O = an alcohol + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 179179Low molecular weight phosphotyrosine protein phosphatase
PRO_0000331562

Sites

Active site151Nucleophile By similarity
Active site211 By similarity
Active site1481Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q55GW2 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: E14FE7B06D8D697B

FASTA17920,470
        10         20         30         40         50         60 
MSADSKNQKK VLFVCLGNIC RSTMAEIVLR GLVHSRGILD DFQIDSAGTS SYHIGDTPDP 

        70         80         90        100        110        120 
RTVQSCNQNM GRAISEESLK HFKSIPLHRA RQFTDEDFSK FDYIFAMDES NLSNIKKVLK 

       130        140        150        160        170 
HSTTKDNHIA TIKRLGEYHT HKKINVEDPY YGDMSNFNIC FNHVHDCLVN FLKEIESLN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000003 Genomic DNA. Translation: EAL73195.1.

3D structure databases

ProteinModelPortalQ55GW2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0189318.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0266663; DDB0266663; DDB_G0267484.
KEGGddi:DDB_G0267484.

Organism-specific databases

dictyBaseDDB_G0267484. acp1.

Phylogenomic databases

eggNOGCOG0394.
KOK14394.
OMAFKSIPLH.
PhylomeDBQ55GW2.
ProtClustDBCLSZ2497297.

Family and domain databases

InterProIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERPTHR11717. PTHR11717. 1 hit.
PfamPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSPR00719. LMWPTPASE.
SMARTSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMSSF52788. SSF52788. 1 hit.
ProtoNetSearch...

Other

PROQ55GW2.

Entry information

Entry namePPAC_DICDI
AccessionPrimary (citable) accession number: Q55GW2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase