Q55GU1 (OSGEP_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep

Gene names

Name:	osgep
ORF Names:	DDB_G0267512

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Ligand	Iron Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 336	336	Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep		PRO_0000331475
Regions
	Compositional bias	319 – 322	4	Poly-Thr
Sites
	Metal binding	110	1	Iron By similarity
	Metal binding	114	1	Iron By similarity
	Metal binding	131	1	Iron By similarity
	Metal binding	295	1	Iron By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q55GU1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 8807F8F6A2254673	FASTA	336	37,202
	10 20 30 40 50 60 MVYIMGFEGS ANKLGIGIVK DDGTILSNIR HTFITPPGEG FLPKDTAKHH RSFILSLVEK 70 80 90 100 110 120 SLEESKLKPS DIDCLAYTKG PGMGPPLRSV AVTVRMLSQL WDRPIVAVNH CIAHIEMGRL 130 140 150 160 170 180 ITGAVDPTIL YVSGGNTQVI SYSLKKYRIF GETIDIAVGN CLDRFARVIQ IPNDPSPGYN 190 200 210 220 230 240 IEQLAKKGKN LIELPYITKG MDVSFSGILS SIEGMVKNKQ NKTQHSVEDL CYSLQEHLFS 250 260 270 280 290 300 MLVETAERAL AHCGQNEVLA VGGVGCNQRL QEMIQQMISQ RNGKSFAIDE RYCIDNGAMI 310 320 330 AWAGYLIFKN GTTTPLSQTT TTQRFRTDQV DVTWRD

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000003 Genomic DNA. Translation: EAL73209.1.
RefSeq	XP_647093.1. XM_642001.1.
3D structure databases
ProteinModelPortal	Q55GU1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q55GU1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0305242; DDB0305242; DDB_G0267512.
GeneID	8615897.
GenomeReviews	Gene locus osgep in contig CM000150_GR.
KEGG	ddi:DDB_G0267512.
Organism-specific databases
dictyBase	DDB_G0267512.
Phylogenomic databases
eggNOG	KOG2708.
GeneTree	EPrGT00050000003004.
HOGENOM	HBG304663.
OMA	RRTYITP.
PhylomeDB	Q55GU1.
ProtClustDB	PTZ00340.
Family and domain databases
InterPro	IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR00329. Gcp_kae1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

OSGEP_DICDI

Accession

Primary (citable) accession number: Q55GU1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	May 24, 2005
Last modified:	November 16, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)